Richard Bayliss

@molecularrichard.bsky.social

AlphaFold was a game changer for this project. AF stories are a bit boring aren't they? It helped really us to make sense of our structural data. With some neat HDX-MS experiments, it all came together. A big thank you to all the authors, it's great to see it published! 3/n doi.org/10.1083/jcb....

Structural characterization and inhibition of the interaction between ch-TOG and TACC3 | Journal of Cell Biology | Rockefeller University Press

Shelford, Burgess, and colleagues present a structural model of the interaction between TACC3 and ch-TOG. They discover Affimers that can inhibit this inte

doi.org