Jennifer A Miles, molecularrichard.bsky.social et al model the Aurora A-Bora-Plk1 ternary complex revealing how Bora bridges both kinases #RefereedPreprint @reviewcommons.org link.springer.com/article/10.1...
I wrote something about why giving negative feedback to your colleagues can be a bit like slaying vampires in The Lost Boys, or something like that. quantixed.org/2025/04/23/f...
Feedback Deficiency: the tricky art of effective peer feedback – quantixed
quantixed.org
A masterclass in molecular imaging - too exciting for (this former NPC-phile's) words!
I’m excited to share our latest research from the Musser Lab, published today in Nature. Using two-color 3D MINFLUX, we directly visualized nuclear import and export events through transport-active nuclear pores. (1/5) www.nature.com/articles/s41...
First post on here to mark the lab's first paper of the year. It's a belter. The product of several collaborations, many techniques skilfully applied and incredible persistence. 1/n doi.org/10.1083/jcb....
Structural characterization and inhibition of the interaction between ch-TOG and TACC3 | Journal of Cell Biology | Rockefeller University Press
Shelford, Burgess, and colleagues present a structural model of the interaction between TACC3 and ch-TOG. They discover Affimers that can inhibit this inte
doi.org
AlphaFold was a game changer for this project. AF stories are a bit boring aren't they? It helped really us to make sense of our structural data. With some neat HDX-MS experiments, it all came together. A big thank you to all the authors, it's great to see it published! 3/n doi.org/10.1083/jcb....
Structural characterization and inhibition of the interaction between ch-TOG and TACC3 | Journal of Cell Biology | Rockefeller University Press
Shelford, Burgess, and colleagues present a structural model of the interaction between TACC3 and ch-TOG. They discover Affimers that can inhibit this inte
doi.org