Multi-Defence
@multidefence.bsky.social
Unravelling the genetic dance of MGEs and bacterial immunity 🧩|Embracing the diversity of research techniques| #BBSRC_sLOLA #Bioinfo #Evol #Biochem #Mathmodel https://sites.exeter.ac.uk/multidefence/
Stimulating keynote from @jojofoth.bsky.social on advancing phage therapy for chronic respiratory infections in cystic fibrosis, addressing key translational challenges from clinical pathways and phage biobanking to delivery, diagnostics, and public engagement at #Microbio26.
Great to see exciting work from @megllewellyn.bsky.social on how expression context shapes the protection provided by bacterial defence systems. Comparing chromosomal and plasmid-encoded systems highlights how regulatory architecture influences defence effectiveness.
DefensePredictor: A machine learning model to discover prokaryotic immune systems #microbiology #prokaryotes #CRISPR #MicroSky @science.org www.science.org/doi/10.1126/...
DefensePredictor: A machine learning model to discover prokaryotic immune systems
Antiphage defense systems protect bacteria from viral infection and have inspired important biotechnologies such as CRISPR-Cas9 while also revealing the evolutionary roots of eukaryotic innate immunit...
science.org
Highlights from our recent participation! Members of the Multi-Defence Consortium presented both talks and posters on phage defence systems — showcasing exciting progress across the field. Great discussions, great science, and we’re excited to share more soon! #MicroEvo25
Highlights from our recent participation! Members of the Multi-Defence Consortium presented both talks and posters on phage defence systems — showcasing exciting progress across the field. Great discussions, great science, and we’re excited to share more soon! #MicroEvo25
Antibiotics & phage infectivity www.findaphd.com/phds/project... (4/4)
Understanding the effects of antibiotics on bacteriophage infectivity at University of Exeter on FindAPhD.com
PhD Project - Understanding the effects of antibiotics on bacteriophage infectivity at University of Exeter, listed on FindAPhD.com
findaphd.com
🔬 Interested in bacterial immune systems & AMR, or how antibiotics affect phage infectivity? Three SWBio DTP PhD project opportunities linked to the MultiDefence consortium are now open (1/4) #PhD #DoctoralTraining #ResearchCarrers #LifeSciences #phagesky #AMR #microsky #PhDPositions
🦠 Defence systems & AMR www.swbio.ac.uk/files/2025/1... www.swbio.ac.uk/programme/ho... (3/4)
swbio.ac.uk
🔬 Interested in bacterial immune systems & AMR, or how antibiotics affect phage infectivity? Three SWBio DTP PhD project opportunities linked to the MultiDefence consortium are now open (1/4) #PhD #DoctoralTraining #ResearchCarrers #LifeSciences #phagesky #AMR #microsky #PhDPositions
🧬 MADS–CRISPR interaction www.findaphd.com/phds/project... (2/4)
Funded PhD SWBio DTP- (CASE) Understanding the molecular mechanism of the MADS bacterial immune system and its synergy with CRISPR-Cas at University of Bristol on FindAPhD.com
PhD Project - Funded PhD SWBio DTP- (CASE) Understanding the molecular mechanism of the MADS bacterial immune system and its synergy with CRISPR-Cas at University of Bristol, ...
findaphd.com
🔬 Interested in bacterial immune systems & AMR, or how antibiotics affect phage infectivity? Three SWBio DTP PhD project opportunities linked to the MultiDefence consortium are now open (1/4) #PhD #DoctoralTraining #ResearchCarrers #LifeSciences #phagesky #AMR #microsky #PhDPositions
🔬 Interested in bacterial immune systems & AMR, or how antibiotics affect phage infectivity? Three SWBio DTP PhD project opportunities linked to the MultiDefence consortium are now open (1/4) #PhD #DoctoralTraining #ResearchCarrers #LifeSciences #phagesky #AMR #microsky #PhDPositions
www.findaphd.com/phds/project... @nebiolabs.bsky.social @multidefence.bsky.social
Funded PhD SWBio DTP- (CASE) Understanding the molecular mechanism of the MADS bacterial immune system and its synergy with CRISPR-Cas at University of Bristol on FindAPhD.com
PhD Project - Funded PhD SWBio DTP- (CASE) Understanding the molecular mechanism of the MADS bacterial immune system and its synergy with CRISPR-Cas at University of Bristol, ...
findaphd.com
More info & tickets see poster and link: sites.exeter.ac.uk/vanhoutelab/... (2/2)
2025 Phage Therapy Workshop - Free Event
November 25th, 2025 at the Spine Building in Liverpool Rising levels of antimicrobial resistance threaten healthcare systems and economies worldwide. Phage therapy has proven to be an effective last-r...
sites.exeter.ac.uk
🦠🧬 Join us for a workshop on Phage Therapy in Liverpool (25 Nov 2025)! A 1-day free event bringing together clinicians, academics, regulators & industry to discuss the future of phage therapy; happening in tandem to a 2-day focus meeting on Microbial Evolutionary Dynamics (1/2)
🦠🧬 Join us for a workshop on Phage Therapy in Liverpool (25 Nov 2025)! A 1-day free event bringing together clinicians, academics, regulators & industry to discuss the future of phage therapy; happening in tandem to a 2-day focus meeting on Microbial Evolutionary Dynamics (1/2)
Happily representing @multidefence.bsky.social at the #EESMicrobiology in Heidelberg! Come to my poster if interested in prophage-mediated phage defence! Also don't miss @emgoodall.bsky.social's talk today, and @alekseiagapov.bsky.social and @davvi36.bsky.social posters!
Presenting a poster about Pseudomonas defence systems at #EESMicrobiology in Heidelberg. If you happen to like it, don't forget to check out our consortium @multidefence.bsky.social
Great to get together in Manchester last week for our consortium’s annual meeting – halfway through our 5-year collaboration! Inspiring discussions, exciting updates, and lots of ideas ahead. Excited for what’s next! 💡🔬🤝 #Science #Microbiology #TeamScience
As part of the @multidefence.bsky.social consortium, we worked with a globally curated dataset of >4,000 P. aeruginosa (from 10.1126/science.adi0908) to reveal differences in the number and composition of defence systems between isolates from (and not from) cystic fibrosis cases 2/n
Passing through the Borders on the train to Manchester for the annual @multidefence.bsky.social meeting
This work was led by the incredible @charlotteechong.bsky.social 💻 🧬 as part of the @multidefence.bsky.social sLoLa consortium funded by @ukri.org BBSRC and in collaboration with a wonderful set of new (and old!) colleagues 9/n
www.findaphd.com/phds/project... A funded PhD studentship is available for a joint project between my lab and @andreashaag.bsky.social @uniofstandrews.bsky.social
Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews on FindAPhD.com
PhD Project - Harnessing Bacterial Viruses to Combat Antibiotic-Resistant Infections at University of St Andrews, listed on FindAPhD.com
findaphd.com
🔬 Three fronts in bacterial defense! At EMBO symposium this week in Paris, our PIs showcased: • @mfwhite2.bsky.social: cyclic nucleotide defence signaling • Prof. Stineke Van Houte: prophage warfare in P. aeruginosa • Prof. Tim Blower: autoregulating toxins & phage defence
We had fantastic poster presentations at the EMBO symposium the Immune System of Bacteria in Paris this week
Coming back to Microbial Warfare session today we have @charlotteechong.bsky.social giving a talk about "Genomic analyses to infer defence system interactions among global Pseudomonas aeruginosa populations" at 12:15
@samriddhigupta.bsky.social gave her poster presentation today at #Microbio25 about discovering new counter-defence systems in prophage genomes
Second poster session starting soon #Microbio25
We also have a couple of poster presentations today 255 from @drramabht.bsky.social, 282 from @anna-k-richmond.bsky.social, 062 from Meg Llewellyn and 068 from Jasmine Thomas-Campbell. All cool stuff about defence systems!
We also have a couple of poster presentations today 255 from @drramabht.bsky.social, 282 from @anna-k-richmond.bsky.social, 062 from Meg Llewellyn and 068 from Jasmine Thomas-Campbell. All cool stuff about defence systems!