A Hot Topics article suggests that combining pharmacological and behavioral approaches to target dysfunctional prefrontal circuits is a promising approach to reduce relapse in addiction @aoceceli.bsky.social @narcatms.bsky.social www.nature.com/articles/s41...

A few years back we started a collaboration to try to work out the mechanisms engaged by DBS for depression. Published today we found that it changes functional networks (expected) but also remodels specific white matter tracts (unexpected). Read more here: www.nature.com/articles/s41...

Deep brain stimulation induces white matter remodeling and functional changes to brain-wide networks - Nature Neuroscience

In a nonhuman primate model, Fujimoto et al. show that deep brain stimulation promotes white matter remodeling and reorganizes brain-wide functional networks, detailing a mechanism through which this ...

nature.com

Pr Kent Berridge, one of the most influential behavioral neuroscientists of the 21st century, will be at the Bordeaux Neurocampus on March 24, 2026, for a lecture on pleasure, desire, and addiction 🤩 @univbordeaux.bsky.social @neurobordeaux.bsky.social www.bordeaux-neurocampus.fr/event/semina...

Seminar - Kent Berridge - Bordeaux Neurocampus

Pleasure, Desire, and Addiction // Venue: centre Broca

bordeaux-neurocampus.fr

Great discussion after The Resevoir on the neuroscience of addiction and recovery. Wonderful panel with Daniela Schiller, @desireebyrd.bsky.social, and Shilpa Taufique. Always inspiring when theater and science meet to explore the human brain. Thank you @richkelley.bsky.social for the invitation!

Discussing The Resevoir this coming Tuesday urldefense.proofpoint.com/v2/url?u=htt...

Neuropsychologist Desiree Byrd and neuroscientists Rita Goldstein and Daniela Schiller join clinical psychologist Shilpa Taufique to discuss the scientific issues behind the new play THE RESERVOIR — ...

Following the 7:00 PM performance of THE RESERVOIR on Tuesday, March 10 at the Linda Gross Theater, audiences are invited to remain for an in-depth exchange between leading researchers in neuroscience...

urldefense.proofpoint.com

Using neuroimaging, @mountsinainyc.bsky.social's Dr. Rita Z. Goldstein, et al. simultaneously examine sex differences & hormonal effects on brain responses to drug cues, and their down-regulation thru cognitive reappraisal, in subjects w/ #SubstanceUseDisorders👉 www.sciencedirect.com/science/arti...

Here, Drs. Carla Agurto, Rita Z. Goldstein, et al. recorded spontaneous speech from initially abstinent individuals with #CocaineUseDisorder (iCUDs) for use in predicting drug use outcomes. Learn More in Biological Psychology👉 www.biologicalpsychiatryjournal.com/article/S000...

Go check out our paper illustrating that objective cognitive-behavioral measures can outperform traditional self-reports when it comes to informing clinical outcomes! This is a promising step towards improving the tools we use to assess severity. @narcatms.bsky.social @aoceceli.bsky.social

Moving Beyond Self-Report in Characterizing Drug Addiction: Using Drug-Biased Behavior to Predict Treatment Completion and Dropout in Heroin-Primary, Medication-Maintained Opioid Use Disorder

Drug addiction is accompanied by enhanced salience attributed to drug over nondrug cues. This bias can be objectively measured and is reliable but und…

sciencedirect.com

Also check out a commentary on these results, which highlights the utility of these drug-biased behavioral measures in clinical addiction research! @narcatms.bsky.social

Improving Treatment Outcome Prediction Beyond Self-Report: The Role of Drug-Biased Behavioral Measures

sciencedirect.com

Natalie McClain@nataliemcclain.bsky.social · 5mo ago

Go check out our paper illustrating that objective cognitive-behavioral measures can outperform traditional self-reports when it comes to informing clinical outcomes! This is a promising step towards improving the tools we use to assess severity. @narcatms.bsky.social @aoceceli.bsky.social

#acnp2026

#acnp2026

Read Methylphenidate and drug memory modulation normalizes brain function in drug addiction on Kudos: www.growkudos.com/publications...

Methylphenidate and drug memory modulation normalizes brain function in drug addiction

Individuals with cocaine use disorder underwent a brain imaging task designed to weaken drug memories by extinguishing reactivity to images that were previously associated with drug use. When methylph...

growkudos.com

A colossal effort from the NARC lab: we reviewed the recent advances in drug addiction research from the lens of the impaired response inhibition and salience attribution model. A one stop shop for theory, severity, recovery, and novel directions. osf.io/preprints/ps...

Our research shows how #cannabis affects the developing brain. I spoke to Dr. Delaney Ruston about how #THC exposure in adolescent rats alters cell communication vital for cognitive function. Watch more: www.youtube.com/watch?v=f2Eb...

🎉Excited to share that Dr. Rita Goldstein, Director of Icahn Mount Sinai's Neuroimaging of Addictions and Related Conditions (NARC) Research Program, has been awarded an @bbrfoundation.bsky.social Distinguished Investigator Grant. CONGRATULATIONS Rita! Learn More👉 bbrfoundation.org/content/bbrf...

Symposium 2 chaired by Rita Goldstein, is focused on dopamine and its function in behaviour outside of the traditionally considered reward research sphere. #EBPS2025

Learn More in Brain Shared orbitofrontal dynamics to a drug-themed movie track craving and recovery in heroin addiction - Greg Kronberg, Ahmet Ceceli, Yuefeng Huang, Pierre-Olivier Gaudreault, Sarah King, Natalie McClain, Nelly Alia-Klein, Rita Z Goldstein 👉 academic.oup.com/brain/articl...

Shared orbitofrontal dynamics to a drug-themed movie track craving and recovery in heroin addiction

Kronberg et al. measured fMRI responses to a drug-themed movie in individuals with heroin use disorder. Responses in the orbitofrontal cortex were biased t

academic.oup.com

Dr. @ericjnestler.bsky.social & @paulkennyphd.bsky.social were thrilled to present Dr. Rita Z. Goldstein w/ the Neuroscience Mentorship Distinction Award at the 17th annual Friedman Brain Institute Neuroscience Retreat! A HUGE CONGRATULATIONS Rita! So we'll deserved💯👏🎉! @mountsinainyc.bsky.social

Congratulations to the 2025 Distinguished Investigator Grantees! . Read the Press Release: ow.ly/oVn050Vk6vx . #mentalhealth #mentalhealthawareness #neuroscience #depression #anxiety #schizophrenia #autism #OCD #PTSD #BPD #bipolardisorder #ADHD #ADD

NARC lab for science!

If anyone is still having trouble accessing Pubmed, this worked for me!

If pubmed is inaccessible at the moment, try @europepmc.org

I always realized one key advantage of tDCS is that the technology can be made really cheap. But didnt realize it could even be disposable systems. Fascinating exploration by Marom Bikson.

An eternally long delay to drug reward In this work, we trained rats to report, so to speak, a subjective estimate of the delay of i.v. cocaine reward Their verdict: few tens of seconds, an eternity for rats which explains why cocaine is so low on their value ladder www.nature.com/articles/s41...

Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction - Neuropsychopharmacology

Neuropsychopharmacology - Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction

nature.com

Grateful for the chance to share my thoughts on responsible use of LLMs in psychology research @spspnews.bsky.social #spsp2025. Here's a summary of my presentation for those who missed it. Thanks to @ashwinia.bsky.social for organizing this panel! How should LLMs be used in psychology research? 🧵

... in understanding how drugs of abuse cause addiction in vulnerable individuals. This knowledge provides an increasingly powerful foundation upon which to develop more effective treatments for substance use disorders. www.science.org/doi/10.1126/...

The biology of addiction

Insights into the biology of addiction and their potential translation into advances in therapy are discussed.

science.org

SAMHSA website is back-up. Now is a great time to download NSDUH data, for those interested in these data.

Hello Bluesky! @vcalhoun.bsky.social, Kent Kiehl and I are teaching our 3-day #fMRI course live online Feb 5 - 7, 2025! #SPM, #ICA, path analysis, #DataScience We've been at it for >20 years & love talking methods & connecting with colleagues! Register at: sites.google.com/dartmouth.ed...

fMRI Course

Instructors

sites.google.com

This paper is magical.

Science News@scinews.bsky.social · 2y ago

Three must read papers for PhD students. #scisky #PhD #science #research #academicsky 1. The importance of stupidity in scientific research Open Access journals.biologists.com/jcs/article/...

Wonderful times #ACNP2025 for the NARC current and former members