Ahmet O. Ceceli
@aoceceli.bsky.social
Incoming assistant professor of psychiatry @ Mt. Sinai. Studying the neuroscience of cognitive control, goals, and habits in health and disease with NIDA K99.
More good news from @acnporg.bsky.social! @narcatms.bsky.social and I will be chairing the panel "Tracking addiction recovery in real time: dense phenotyping of risk and resilience" at ACNP 2027, ft talks from @nguyenheartylab.bsky.social, Woo-Young Ahn, Paul Glimcher, and me. Don't miss!
A Hot Topics article suggests that combining pharmacological and behavioral approaches to target dysfunctional prefrontal circuits is a promising approach to reduce relapse in addiction @aoceceli.bsky.social @narcatms.bsky.social www.nature.com/articles/s41...
Restoring prefrontal function with dopaminergic enhancement of memory updating in addiction - Neuropsychopharmacology
Neuropsychopharmacology - Restoring prefrontal function with dopaminergic enhancement of memory updating in addiction
nature.com
Thrilled to receive a 2027 ACNP Travel Award! One of my favorite parts of this job is getting immersed in the science @ ACNP meetings and learning from so many brilliant people. Thanks @acnporg.bsky.social for recognizing my work + helping me become a regular! @sinaibrain.bsky.social
@narcatms.bsky.social and I wrote a @npp-journal.bsky.social Hot Topic highlighting the synergistic combination of memory updating and dopaminergic enhancement as a potential component of addiction interventions. Check it out here: www.nature.com/articles/s41... @sinaibrain.bsky.social
Restoring prefrontal function with dopaminergic enhancement of memory updating in addiction - Neuropsychopharmacology
Neuropsychopharmacology - Restoring prefrontal function with dopaminergic enhancement of memory updating in addiction
nature.com
Update: the book is now officially out! Neuroeconomics: Core Topics and Current Directions is available from Springer here: link.springer.com/book/10.1007... Huge thanks again to @thepsychologist.bsky.social, @dfareri.bsky.social, and all of the contributors.
Neuroeconomics: Core Topics and Current Directions
This book provides comprehensive coverage of core topics and recent advances in the field of neuroeconomics and highlights emerging trends in the field.
link.springer.com
David V. Smith@dvsmith.bsky.social · last yr.🚨📚 New book! I’m thrilled to share that our edited volume, Neuroeconomics: Core Topics and Current Directions (Springer Nature), will be out later this year. Co-edited with @thepsychologist.bsky.social and @dfareri.bsky.social — huge thanks to all our brilliant contributors. 🧵 (1/12)
Check out our new review titled "Contributions of default mode network to subjective valuation and maladaptive decision making" now out in Current Opinion in Behavioral Science! @dfareri.bsky.social authors.elsevier.com/a/1n8Js8MqMi...
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authors.elsevier.com
Where, exactly, does learning happen in the brain? Out today in @nature.com, we identify a synaptic locus of birdsong learning and show that the circuit can be tuned to make birds learn faster - but at a cost. Read on👇 #neuroskyence 🧪 #prattle 💬 #bioacoustics Shareable link: rdcu.be/fiyrS
A synaptic locus of song learning - Nature
Combining a computational framework and optogenetic and chemogenetic manipulations within and downstream of the cortico-basal ganglia circuit identifies the specific cortico-basal ganglia synapse...
nature.com
@nataliemcclain.bsky.social's "Metropolis of the Mind" reimagines the brain as a city. Different buildings (distinct brain regions) are connected by bridges (neural pathways). Collapsed bridges represent neural pathways weakened by #Addiction. VOTE NOW for #ArtoftheBrain Image # 28 👉 Most 🧡s wins!
New Annual Review with @nathanieldaw.bsky.social: “Planning in the Brain: It's Not What You Think It Is.” We argue that the brain's 'planning' machinery is mostly used for learning from simulated experience, and that thinking prospectively at decision time is just one special case of this process.
Planning in the Brain: It's Not What You Think It Is
The neuroscience of planning has long been analogized to search algorithms in artificial intelligence (AI), which simulate future actions to guide immediate choices. We argue that advances in both neu...
annualreviews.org
🚨Preprint Alert🚨 Our new preprint 'A Scalable fMRI Estimate of Basal Ganglia Brain Tissue Iron for Use in Developmental and Translational Neuroscience' is live!! lnkd.in/gpG9naba
This link will take you to a page that’s not on LinkedIn
lnkd.in
SCORE, a collaboration of 865 researchers, is now released as three papers in Nature, six preprints, and a lot of data (cos.io/score/). SCORE examined repeatability of findings from the social-behavioral sciences and tested whether human and automated methods could predict replicability.
SCORE | Center for Open Science
SCORE shows that there is no shortcut to producing credible research findings, and there is no single indicator of trustworthiness. Research progress depends on transparency, rigor, and establishing r...
cos.io
Excited to share our new paper proposing a new computational model accounting for the dynamic interaction btw drug #craving and #decision-making, led by Kaustubh Kulkarni, MD/PhD rdcu.be/fab6B #AddictionScience #Neuroscience #ComputationalPsychiatry #BehavioralScience
A computational mechanism linking momentary craving and decision-making in alcohol drinkers and cannabis users - Nature Mental Health
This study investigated the computational mechanisms linking momentary craving and decision-making in people with moderate to high addiction risk levels for alcohol or cannabis use, uncovering differe...
nature.com
Semaglutide reduces depression risk by 44%, anxiety by 38%, and substance use disorder by 47% (other GLP1s had lower or no effect). That said, it the failed Alzheimer/GLP1 trial taught us something, it's that confirmatory RCTs are essential. linkinghub.elsevier.com/retrieve/pi...
Association between GLP-1 receptor agonist use and worsening mental illness in people with depression and anxiety in Sweden: a national cohort study
People with diabetes have an elevated risk of developing depression, anxiety, and suicide. GLP-1 receptor agonists are licensed to treat diabetes and …
linkinghub.elsevier.com
Precision reward/affect fMRI study out now in HBM! onlinelibrary.wiley.com/doi/10.1002/... @dvsmith.bsky.social @olinotom.bsky.social @coopersharp.bsky.social and @shenghanwang.bsky.social Intensively sampled task + rest fMRI data with behavioral manipulation openly available on OpenNeuro! (1/2)
Precision Imaging for Intraindividual Investigation of the Reward Response
We present open data for an intensively sampled precision imaging study including multiple reward-related tasks and a behavioral mood manipulation. Our initial analysis found low test–retest reliabil....
onlinelibrary.wiley.com
Matt Mattoni@mattmattoni.bsky.social · 10mo ago🚨🚨New precision imaging study and open dataset 🚨🚨 Featuring almost 200 functional runs acquired in 3-4d intervals and behavioral manipulations focused on intraindividual study of the reward response - The Night Owls Scan Club (NOSC) With @dvsmith.bsky.social and @olinotom.bsky.social!
New review/theory paper out with Julie Bugg, Chris Nuno, and Changrun Huang. The upshot is that we don’t know for certain why it’s so hard to get people to engage proactive control from trial to trial (but it’s fun to think about it and speculate!).
Changrun Huang@changrun-huang.bsky.social · 5mo agoOur recent review led by Julie Bugg is out in PB&R. We explore why advance warnings to pay attention often fail to improve proactive cognitive control in conflict tasks. We introduce the TEPID framework to explain this. link.springer.com/epdf/10.3758...
Discussing The Resevoir this coming Tuesday urldefense.proofpoint.com/v2/url?u=htt...
Neuropsychologist Desiree Byrd and neuroscientists Rita Goldstein and Daniela Schiller join clinical psychologist Shilpa Taufique to discuss the scientific issues behind the new play THE RESERVOIR — ...
Following the 7:00 PM performance of THE RESERVOIR on Tuesday, March 10 at the Linda Gross Theater, audiences are invited to remain for an in-depth exchange between leading researchers in neuroscience...
urldefense.proofpoint.com
Also check out a commentary on these results, which highlights the utility of these drug-biased behavioral measures in clinical addiction research! @narcatms.bsky.social
Improving Treatment Outcome Prediction Beyond Self-Report: The Role of Drug-Biased Behavioral Measures
sciencedirect.com
Natalie McClain@nataliemcclain.bsky.social · 5mo agoGo check out our paper illustrating that objective cognitive-behavioral measures can outperform traditional self-reports when it comes to informing clinical outcomes! This is a promising step towards improving the tools we use to assess severity. @narcatms.bsky.social @aoceceli.bsky.social
Go check out our paper illustrating that objective cognitive-behavioral measures can outperform traditional self-reports when it comes to informing clinical outcomes! This is a promising step towards improving the tools we use to assess severity. @narcatms.bsky.social @aoceceli.bsky.social
Moving Beyond Self-Report in Characterizing Drug Addiction: Using Drug-Biased Behavior to Predict Treatment Completion and Dropout in Heroin-Primary, Medication-Maintained Opioid Use Disorder
Drug addiction is accompanied by enhanced salience attributed to drug over nondrug cues. This bias can be objectively measured and is reliable but und…
sciencedirect.com
Excited to share this in final form @sfnjournals.bsky.social: An Open-Source Restraint System for Magnetic Resonance Imaging in Awake Rats www.eneuro.org/content/13/2... if anyone wants to try doing it, give us a call! Happy to help you get going!
An Open-Source Restraint System for Magnetic Resonance Imaging in Awake Rats
Magnetic resonance imaging (MRI) is a critical tool for translational neuroscience, but preclinical studies frequently rely on anesthesia, which alters neural activity and limits comparison with human...
eneuro.org
New paper from the lab now out online! @changrun-huang.bsky.social asked whether people use informative pre-cues to up-regulate cognitive control in the spatial Stroop task. Surprisingly, they do not, and we rule out some possible reasons why. Enjoy!
APA PsycNet
psycnet.apa.org
I reviewed 5+ fMRI papers on response inhibition within roughly the last year, and the same points come up over and over again. So I wrote a short note last week entitled "The unique limitations of BOLD-fMRI in the study of response inhibition". You can read it here. osf.io/preprints/ps...
OSF
osf.io
Check out our new preprint documenting how Mindfulness-Oriented Recovery Enhancement rebalances neural responses to drug and natural reward cues in opioid use disorder! W/ Yuefeng Huang, @narcatms.bsky.social, @drericgarland.bsky.social et al @sinaibrain.bsky.social www.medrxiv.org/content/10.6...
Mindfulness-Oriented Recovery Enhancement rebalances prefrontal responses to drug and natural reward cues in opioid use disorder
Despite decades of clinical implementation of medications for opioid use disorder (OUD), overdose mortality rates remain high, underscoring a critical gap in treatments that target brain mechanisms dr...
medrxiv.org
Students need to remember that Inigo Montoya method for emails and greetings: "Hello, my name is Inigo Montoya. You killed my father. Prepare to die.” Polite Greeting Name Relevant Personal Link Manage Expectations Keep it BRIEF.
bergelsonlab@bergelsonlab.bsky.social · 6mo agoam i the only 1 who wishes ppl would remind me that we've interacted before if it's plausible i've forgotten? I've had like 3-4 emails that seems like 'cold emails' ab research opportunities but then it turns out we've exchanged emails in the past & it's awkward to not have realized this? just me?
🚨 Prospects of GLP-1 Therapies for Addiction and Mental Health Comorbidities—Quo Vadis? jamanetwork.com/journals/jam... @jamapsychiatry.com
GLP-1 Therapies for Addiction and Mental Health Comorbidities
This narrative review discusses the current landscape of glucagon-like peptide-1 therapies in the context of alcohol and other substance use disorders, mental health considerations, and gaps and oppor...
jamanetwork.com
Wrapping up my 4th #ACNP while savoring this view. Grateful to the presenters as I learned a ton from the panels and posters at #acnp2026. Looking fwd to returning in 2027! @acnporg.bsky.social @sinaibrain.bsky.social
ACNP@acnporg.bsky.social · 7mo ago📸 One last favor: Share your favorite photo from the meeting and tag us! We’d love to see #ACNP2026 through your eyes. Until next year... stay inspired!
Come talk addiction cogneuro (or anything else really...) with me at poster TH54 @5p! @acnporg.bsky.social @sinaibrain.bsky.social #acnp2026
Ahmet O. Ceceli@aoceceli.bsky.social · 7mo agoIn attendance with the @narcatms.bsky.social lab! Excited to see old friends and meet new ones. And for everyone to check out poster TH54 on Thursday 5-7p where I'll talk about goals and habits in addiction! #acnp2026
In attendance with the @narcatms.bsky.social lab! Excited to see old friends and meet new ones. And for everyone to check out poster TH54 on Thursday 5-7p where I'll talk about goals and habits in addiction! #acnp2026
ACNP@acnporg.bsky.social · 7mo agoDay 1 of #ACNP2026 is officially underway! We are starting the morning strong with the President’s Plenary, followed by a dynamic Data Blitz session.
