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Nikita Kozhushko
@nikitakozhushko.bsky.social
(she/her) | 🎓MSc, BSc (Hons) | PhD student at @Cambridge_Uni with an interest in PD/AD genomics, neurodegeneration and all things mitochondria. Previously at NIH.All views are my own 🫡
Congratulations @kev-in-situ-et.bsky.social and the whole team on in situ cryo-ET images of OA-induced mitochondria damage and Parkin-dependent mitophagy out now tinyurl.com/25b82cp4. We couldn't have done it without in situ guru @wilflinglab.bsky.social and mito guru @samlewis.bsky.social .‬
Last week's mitophagy news is packed with papers!! 📚🧑‍💻 Full list 👇 biomed.news/bims-tofagi/... Highlights: -in vitro reconstitution of receptor-mediated mitophagy reveals key principles -cytosolic phosphoUbiquitin inhibits proteasomal activity and is neurotoxic Thanks to @biomednews.bsky.social
Parkinson’s might start in the kidneys. www.nature.com/articles/s41...
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease - Nature Neuroscience
Yuan et al. find that the kidney can serve as a site of initiation for the spread of pathological α-synuclein to the brain, contributing to the development of Parkinson’s disease (PD) and providing a ...
nature.com