After a quite long process, we are happy to share the last version of our article describing unexpected results regarding the coupling between local cell death and proliferation (heroic revision effort from @ralitzastaneva.bsky.social ) urldefense.com/v3/__https:/...

A global response contributes to tissue size robustness upon local induction of apoptosis

Tissue resilience requires tight coupling between cell proliferation, growth, and death.1,2,3,4It is assumed to be based on compensatory proliferation…

urldefense.com

Happy to share our new review on biophysical principles of cell competition and elimination: www.cell.com/trends/cell-... With @bladoux.bsky.social and @rmmege.bsky.social, we discuss mechanical fitness, how loser cells are removed through various strategies and how forces can effect their fate

Really happy to share my PhD story about the regulation of developmental speed in the Drosophila eye 🪰😃👀, which is now published @embojournal.org: link.springer.com/article/10.1... Grateful to everyone who make this possible, particularly F. Schweisguth @pasteur.fr @devstempasteur.bsky.social

I’m pleased to share our latest preprint (my first as 1st-author) from Jérôme Gros’ group (@jeromegros.bsky.social), now on bioRxiv. It reports actin and myosin dynamics during epithelial remodeling in avian gastrulation. (doi: doi.org/10.64898/202...)

Actin and myosin dynamics during epithelial remodeling in avian gastrulation

Epithelial remodeling is powered by contractile forces exerted by the actomyosin cytoskeleton. In invertebrates, pulsatile contractile flows of the medio-apical actomyosin cortex have been shown to be...

doi.org

Are you investigating cell tissues and interested in stress patterns? TFM + BISM reveals them! 👇 With @luanger.bsky.social and P. Marcq, we summarise the applicability across different exp. conditions regularly used in the @bladoux.bsky.social @rmmege.bsky.social lab. Full pipeline on Lucas GitHub!

Benoit Ladoux@bladoux.bsky.social · 8mo ago

Tissue stress measurements — our latest preprint is out: arxiv.org/abs/2512.00550 (publication coming soon!) Fantastic work by the three musketeers — @luanger.bsky.social, @andreasschoenit.bsky.social and @fanny-wodrascka.bsky.social — in collaboration with P. Marcq!

How is developmental speed regulated ? 🪰 Happy to share my PhD story from Schweisguth Lab @devstempasteur.bsky.social. Here we show that cellular NAD+ availability and redox constrain developmental speed in the fly eye. www.biorxiv.org/content/10.1... A big thanks to everyone involved!

We (with @nicolasdray.bsky.social @zenlabpasteur.bsky.social) are happy to release officially FishFeats, our #napari plugin to streamline 3D smFish/RNA quantification! 🎊 Available here: github.com/gletort/Fish... user documentation: gletort.github.io/FishFeats/

How can we investigate the mechanical state of cells within a tissue, assessing if they are under compression or tension? @luanger.bsky.social and I highlight methods in a short 🧵 with @epimechfc.bsky.social

epithelial mechanics fan club@epimechfc.bsky.social · last yr.

Tissues are dynamic and investigating cellular mechanical states can be crucial for understanding biological processes. But how to do it? We are @andreasschoenit.bsky.social and @luanger.bsky.social from @bladoux.bsky.social / @rmmege.bsky.social lab highlighting ways to assess tissue stresses.

Thrilled to share our new manuscript on how force transmission can regulate mechanical cell competition! Fun collaboration between the @bladoux.bsky.social / @rmmege.bsky.social and the Doostmohammadi group combining experiments and simulations. Main points below 👇 www.biorxiv.org/content/10.1...

Force transmission is a master regulator of mechanical cell competition

Cell competition is a tissue surveillance mechanism for eliminating unwanted cells and as such is indispensable in development, infection and tumorigenesis. Although different biochemical mechanisms a...

biorxiv.org

Very happy to share my first story in @levayerr.bsky.social lab, where we show that localized apoptosis drives JNK-dependent developmental delay to ensure global tissue size robustness 🪰

bioRxiv Developmental Biology@biorxiv-devbio.bsky.social · 2y ago

Developmental delay ensures global tissue size robustness upon local induction of apoptosis https://www.biorxiv.org/content/10.1101/2024.12.21.629882v1