Very pleased to finally share the main story from my PhD, now published in @natcomms.nature.com ! 🎉 Using a sea anemone we discovered and characterised epithelial cell extrusion as the mechanism underlying starvation-induced cell loss. 🔗 Open-access article: www.nature.com/articles/s41...

Epithelial cell extrusion underlies starvation-induced cell loss in a sea anemone - Nature Communications

Epithelial cell extrusion in a sea anemone shares key hallmarks with bilaterians and is dynamically regulated by nutritional status. During starvation-induced body shrinkage, extrusion likely contribu...

nature.com

Looking for a PhD? Applications are now open for PhD positions at the Max Delbrück Center. 🧵 www.mdc-berlin.de/career/jobs/...

This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...

Basement membrane turnover controls cell shape

Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...

cell.com

And also, for the story: www.iledefrance-meudon.cnrs.fr/fr/personne/...

Jean-Yves Tinevez@jytinevez.bsky.social · 4w ago

Congratulations to superstar and awesome colleague Gaëlle Letort @gaellel.bsky.social, bioimage analyst extraordinaire for THE CRYSTAL MEDAL OF THE CNRS 2026!!! 🥳🎉🕺🦄🥳 We work with amazing people www.insb.cnrs.fr/fr/personne/...

Congratulation @gaellel.bsky.social for the crystal medal ! So well deserved, you've been transformative for the democratisation of image analysis and deep learning. www.insb.cnrs.fr/fr/talents/c...

CNRS@cnrs.fr · 4w ago

#TalentsCNRS 🏅 Le CNRS décerne ses médailles de cristal et cristal collectif 2026, récompensant des femmes et des hommes ayant contribué à l’avancée des savoirs et à l’excellence de la recherche française. Félicitations 👏 👉 www.cnrs.fr/fr/actualite... 👉 www.cnrs.fr/fr/actualite...

Thrilled to share our new paper on cell extrusion. A beautiful study with a tremendous amount of data, led by the fantastic @fanny-wodrascka.bsky.social ! www.biorxiv.org/content/10.6...

Les nouvelles règles envisagées pour l'ANR sont plus qu'inquiétantes. Elles porteraient un immense coup d'arrêt à la recherche fondamentale en France, surchargeraient les jeunes chercheurs, et n'attendraient sans doute même pas leur objectif (apparent) de réduction du nombre de candidatures

Levayer Lab@levayerr.bsky.social · 4w ago

Si les nouvelles règles de l'éligibilité de l'ANR sont bien réelles, alors je ne comprends pas quelle est la logique sous jacente. Au vu de la pyramide des ages, forcer une collaboration avec chercheurs(ses) <10 ans post thèse va de facto exclure 80% des candidats.

🪲🪰 Our preprint is out! This was a team effort with @wolframponisch.bsky.social, @matthewabenton.bsky.social and Ewa Paluch. We asked whether Drosophila and Tribolium use the same cell behaviours to fold their embryos during gastrulation. 🧵👇 www.biorxiv.org/content/10.6...

Morphospace analysis reveals divergent cellular behaviours driving tissue internalisation during insect gastrulation

During gastrulation, embryonic epithelia undergo large-scale remodelling to internalise the mesoderm. Whether the cellular mechanisms underlying these tissue deformations are conserved across species ...

biorxiv.org

Si les nouvelles règles de l'éligibilité de l'ANR sont bien réelles, alors je ne comprends pas quelle est la logique sous jacente. Au vu de la pyramide des ages, forcer une collaboration avec chercheurs(ses) <10 ans post thèse va de facto exclure 80% des candidats.

New research from @fpichaud.bsky.social and University of Seville researchers found that developing fruit fly retinas behave like metamaterials, folding from flat cellular patterns into precise 3D structures. www.ucl.ac.uk/life-science... #UCLLifeSciences #Biomaterials #Metamaterials

Fly eyes reveal nature's blueprint for metamaterials

Scientists have discovered that fly eyes develop as natural programmable metamaterials, revealing an "origami" blueprint that could inspire biomaterials, tissue engineering and regenerative medicine.

ucl.ac.uk

Definitely check out the Preprint by Lerchbaumer et al. Lerchbaumer, G., Simoes, S., Etemadi, E., Zidan, F., Erdemci-Tandogan, G. and Tepass, U. (2026). E-cadherin clustering as a regulator of morphogenesis. bioRxiv. doi.org/10.64898/202...

E-cadherin clustering as a regulator of morphogenesis

Cell adhesion enables animal multicellular development. E-cadherin and the cadherin-catenin adhesion complex at adherens junctions are engaged in dynamic interactions with actomyosin generated contrac...

doi.org

🚨 New pre-print alert! 🚨 Adult neural stem cell state and fate decisions are hidden within transcriptional heterogeneity. To find out how we decoded these heterogeneities to identify a molecularly encoded quiescence cycle, check out the pre-print on bioRxiv! doi: doi.org/10.64898/202...

After a quite long process, we are happy to share the last version of our article describing unexpected results regarding the coupling between local cell death and proliferation (heroic revision effort from @ralitzastaneva.bsky.social ) urldefense.com/v3/__https:/...

A global response contributes to tissue size robustness upon local induction of apoptosis

Tissue resilience requires tight coupling between cell proliferation, growth, and death.1,2,3,4It is assumed to be based on compensatory proliferation…

urldefense.com

I wanted to like QED's new 1% preprint ranking. I really did. But the more I looked at the data, the more uncomfortable it made me. Here is my full peer review. open.substack.com/pub/blekhman...

My Peer Review of The 1%

I wanted to like QED's new 1% ranking. I don't.

open.substack.com

[ #VeilleESR #LPPR ] Durcissement des règles d'attribution pour l'appel à projets générique ANR. Notamment : réduction du nombre de dépôts et augmentation du délais de carence. L'argumentaire est : plus les scientifiques ont besoin de l'ANR, moins il faut que les scientifiques sollicitent l'ANR.

Un pétition du collège des sociétés savantes pour mettre en avant le rôle de la recherche dans la campagne politique à venir et rappeler le sous investissement chronique en France depuis 20 ans. N'hésitez pas à faire ciculer recherche-publique-2027.fr

Am I in the 1% thinking that after years of debates showing that there is no proper quantitative metrics to quantify article quality and impact, letting AI decides on its own the ranking of research article is a very bad move ? Metrics as usual will be weaponised and used for wrong purpose (see IF)

Our Stem Cell Course #ASCB is back! After 2nd day, @institutpasteur.bsky.social @tajbakhshlab.bsky.social, @zenlabpasteur.bsky.social, Barbara Gayraud-Morel, and great interactive students. Laurence Daheron, Frank Yates, Michel Cohen-Tannoudji covered pluripotency and generating hiPSCs. Great team!

Congrat for the all awardees (and sorry for those who didn't get it). Very few awardees from France this year (specially in biology), a result of long term under-investment ? (The less you put in...the less you get).

European Research Council (ERC)@erc.europa.eu · last mo.

The results of the Advanced Grants 2025 are here! Out of 3,329 applicants, 319 leading researchers have been awarded an ERC Advanced Grant. Congratulations to all! 🎉 Curious to know more ? 👉 buff.ly/uiU9x5K #ERCAdG #FrontierResearch

I missed the chance to meet fly colleagues at the EMBO Crete meeting, but I am also enjoying very much the #Cellmodelinginspaceantime @cshlnews.bsky.social (and the current 21°C...). Exciting modeling and quantitative approches all other the place !

Studying viola seed sequential balistic popping (driven by dessication) to generate zipping actuator. A nice example of bioinspired design www.science.org/doi/10.1126/...

As Editor of @dev-journal.bsky.social I get asked "What are you doing about your impact factor?" In our new editorial we say: Ask not what Dev can do for the impact factor. Ask what you can do for Dev's IF The IF is about how we all cite, review & assess each other's work doi.org/10.1242/dev....

The elephant in the room: impact factor

Summary: This Editorial offers an honest look at impact factor trends in developmental biology, explains how Development serves its community, and makes the case that sustaining developmental biology ...

doi.org

This will be on 26 June in Paris! 🤩You are welcome to join and participate in this exciting 1-day conference at the College de France on Biological computational accross areas of biology. Fantastic speakers. Free, no registration, at the heart of Paris on a lovely season. Worth planning a weekend…?

Thomas Lecuit@thomaslecuit.bsky.social · 3mo ago

Here is the announcement of a Symposium @college-de-france.fr on 26 June on Information Flow and Computation in Biological systems. A great line of speakers on a variety of topics from embryogenesis to neuroscience, immunology and microbiology. Free entrance, come if you are in Paris end of June 🤩

📢 We are looking for a Junior Group Leader to join us at @institutcurie.bsky.social! Having joined the department just over a year ago, I can honestly say that it is an exceptionally stimulating and supportive scientific environment, filled with outstanding colleagues — all in the heart of Paris.

🏅 Congrats to Elisa Gomez‑Perdiguero & Brice Bathellier, winners of the 2026 Vallery‑Radot Prize ! 👏 Their work advances our understanding of immune cell origins & how the brain processes sound — showcasing Pasteurian excellence. 💙 @labnf.bsky.social

Please repost !! SANTA CRUZ DEVELOPMENTAL BIOLOGY CONFERENCE 2026. Deadline to register your abstracts for the meeting is Monday June 1. Please get those abstracts in ! scdb2026.sites.ucsc.edu

Our latest manuscript on (Harry Potter and) the effect of elevated temperature on embryonic development in flies. Even a small increase in temperature causes developmental defects, indicating problems in the face of global warming! www.nature.com/articles/s41...

Elevated temperature fatally disrupts nuclear divisions in the early Drosophila embryo - Nature Communications

Kale et al. show that nuclear divisions are defective at elevated temperature, leading to gastrulation defects and embryo lethality. Their work finds that F-actin – microtubule interactions during mit...

nature.com

This exciting paper is now out in PNAS: www.pnas.org/doi/10.1073/...

3D epithelial cell topology tunes signaling range to promote precise patterning | PNAS

Cell behaviors in multicellular organisms are coordinated via both diffusible molecules and by signals based on direct cell&ndash;cell contacts. The mode...

pnas.org

Yanlan Mao@yanlanmao.bsky.social · 12mo ago

An exciting new paper from the lab! Check it out:

Happy to share our new review on biophysical principles of cell competition and elimination: www.cell.com/trends/cell-... With @bladoux.bsky.social and @rmmege.bsky.social, we discuss mechanical fitness, how loser cells are removed through various strategies and how forces can effect their fate

💥 🚀 New preprint! 🎉🥳 How do hundreds of organelles organize themselves into near-perfect patterns inside a cell, without a blueprint? We dive deep into how basal bodies (BBs) self-organize in MCCs - and how actin actively tunes their dynamics into order 🍪 🧵👇 (1/17)