MMI congratulates Evan Lind to promotion to full Professor, and Isabella Rauch @rauchlab.bsky.social to receiving tenure!

MMI faculty member Isabella Rauch @rauchlab.bsky.social gave the @globalimmuno.bsky.social seminar today. You can find the recording on youtube at urldefense.com/v3/__https:/...

Interested in microbiology, immunology, and host-pathogen interactions? Come work with us! Our department at OHSU is opening a search for a new tenure-track faculty position. See the job advertisement for details. Please share within your networks! www.nature.com/naturecareer...

Faculty Position in Molecular Microbiology and Immunology - Portland, Oregon job with Oregon Health & Science University (OHSU) - Molecular Microbiology and Immunology | 12858852

The Department of Molecular Microbiology and Immunology at OHSU invites applications for a tenure-track Assistant or Associate Professor position.

nature.com

Thank you @miketilapia.bsky.social for giving a great talk today about exciting findings from screens using the pathogen effector ORFome (also lovingly called the “evil”ome 😈).

The Department of Molecular Microbiology and Immunology is looking to grow! We opened a position for an assistant or associate professor, please distribute ! facultycareers-ohsu.icims.com/jobs/39006/a...

🚨Preprint alert ! Alexis Gibson, a @hhmi-science.bsky.social Hannah Grey fellow, reports on our fun collaboration with PNNL. We used standard label-free MS to analyze caspase cleavage products in primary intestinal epithelial cells post inflammasome activation. www.biorxiv.org/content/10.6... 1/2

Thank you to Megan Orzalli @virulentmind.bsky.social for giving an exciting and thought provoking talk for our seminar series. The cell and tissue type we study infection in matters!

Glad to see this news story highlighting our recent lipid interactome database, a resource we hope will help the broader scientific community. @ohsummi.bsky.social @ohsunews.bsky.social news.ohsu.edu/2026/02/25/n...

A warm welcome to our new Department chair, Fikadu Tafesse @tafesselab.bsky.social !!

@tafesselab.bsky.social · 6mo ago

Big career update:  I’m honored and humbled to serve as Chair of the Department of Molecular Microbiology & Immunology at Oregon Health & Science University (OHSU). Looking forward to what we’ll build together! @ohsummi.bsky.social @ohsunews.bsky.social

Can we improve peer review? We think we can! Check out an experiment I helped with as part of @solvingforsci.bsky.social 's mission to make science better. And if you don't want to read the whole bioRxiv manuscript, here's an overview of the main findings: solvingfor.org/news-posts-d...

The Results are In: Preview The Discovery Stack Pilot Paper

Reimagining Peer Review: Feasibility and Value of a Scientist-Designed, Metric-Driven Model

solvingfor.org

Richard Sever@richardsever.bsky.social · 9mo ago

Always great to see peer review experiments with actual data. SolvingForScience distinguish Quality (Q) & Impact (I) scores for papers. Q scores are based on a peer-improvement phase, followed by an I assessment by a different group. Unsurprisingly I varies more than Q 1/2 doi.org/10.1101/2025...

Congratulations to the Rauch lab @rauchlab.bsky.social on their newest publication!

Bella Rauch@rauchlab.bsky.social · 10mo ago

Check out our new publication, a collaboration with Giovanni Luchetti and Vishva Dixit @ Genentech. We show that the E.coli effector NleL inhibits intestinal epithelial cell extrusion after #inflammasome activation via degrading the kinases ROCK1 and 2!! www.nature.com/articles/s41... Explainer 1/8

Last week we had another amazing department retreat, expertly organized by @laurenrodda.bsky.social and @jnpruneda.bsky.social . Thank you to our fantastic invited speaker @harmitmalik.bsky.social and all the trainees for a day of wonderful science discussions.

Join us at the amazing Midwinter Conference of Immunologists in January 2025 in beautiful Asilomar! 🚨There is a travel grant for underrepresented trainees, apply now! www.cvent.com/c/abstracts/... #blackinImmuno #BlackinMicro #Sacnas

Midwinter Conference of Immunologists@midwinter-immun.bsky.social · 12mo ago

Gianna Hammer & @brodskyigorlab.bsky.social are co-organizing the 64th annual Midwinter Conference of Immunologists Jan 24-27, 2026. It's a wonderful meeting with broad topics, incredible speakers, fantastic location & lots of awards for trainees. Can't wait to see you there! www.midwconfimmunol.org

The Trump admin is erasing critical federal data - including climate trends, water quality, wildfire risk, public health stats, and pollution monitoring. When the data goes dark, the American lives are at risk. This is how To Sabatoge A Nation👇 zurl.co/slECM

Trump’s Cuts Are Making Federal Data Disappear

Online tools that professionals use for everything from diagnosing diseases to calculating insurance payouts are going dark.

zurl.co

Congratulations to Bahareh Ajami and her lab @baharehajami.bsky.social ! Dr. Ajami and her team of 6 are studying one of the most promising theories in ALS immunology today. alsnorthwest.org/research-app...

Congratulations to @tafesselab.bsky.social for promotion to Full Professor with tenure!!! Well deserved!

Check out the mucosal Immunology podcast episode with MMI faculty member @rauchlab.bsky.social

Mucosal Immunology@mucosalimmunol.bsky.social · last yr.

It’s #MucosalMonday and the June episode of the Mucosal Immunology Podcast is out with @rauchlab.bsky.social @marionbrunck.bsky.social, @ashu-mangalam.bsky.social, @kknoop.bsky.social and more! Subscribe and follow on your favorite podcast platform. open.spotify.com/episode/5H1k...

It’s finally out! Started this project as a PhD student in the @holthuislab.bsky.social lab & finished by my PhD student. Full-circle moment and the end of an era. 😊 Thanks to Gaelen and everyone who made this happen. @ohsummi.bsky.social @ohsunews.bsky.social pubmed.ncbi.nlm.nih.gov/40473211/

Characterization of C. elegans sphingomyelin synthases through heterologous expression - PubMed

Sphingomyelin (SM) is a major component of mammalian cell membranes and particularly abundant in the myelin sheath that surrounds nerve fibers. Its production is catalyzed by SM synthases SMS1 and SMS...

pubmed.ncbi.nlm.nih.gov

Excited to share our latest preprint! Using integrated global lipidomics and proteomics, we show that SARS-CoV-2 variants induce conserved changes in host lipid metabolism pathways. Congrats to Scotty for leading the work. @ohsummi.bsky.social @ohsunews.bsky.social www.biorxiv.org/content/10.1...

Multi-Omic Profiling Identifies Conserved Metabolic Pathways Critical for SARS-CoV-2 Variants Infection

The rapid evolution of SARS-CoV-2 has led to the emergence of numerous variants with en-hanced transmissibility and immune evasion. Despite widespread vaccination, infections persist, and the mechanis...

biorxiv.org

This cool study on compounds that can kill Plasmodium inside mosquitoes and can be applied to bed-nets was contributed to by the Riscoe lab at MMI!

Kristin Michel@kmichel.bsky.social · last yr.

Excellent new study from the Catteruccia lab, co-led by Alexandra Probst and Douglas Paton www.nature.com/articles/s41...

Congratulations to the Tafesse lab on their recent publication on the effects on timing in repeat vaccinations!

@tafesselab.bsky.social · last yr.

Have you ever wondered how repeated vaccination shapes our immune responses, and whether timing between doses matters? Check out our latest work! @ohsunews.bsky.social @ohsummi.bsky.social www.nature.com/articles/s43...

Congratulations to the groups of Eric Barklis and @tafesselab.bsky.social for reporting an analysis of factors that regulate HIV-1 fusion in reverse pmc.ncbi.nlm.nih.gov/articles/PMC...

Analysis of Factors That Regulate HIV-1 Fusion in Reverse

Based on observations that HIV-1 envelope (Env) proteins on the surfaces of cells have the capacity to fuse with neighboring cells or enveloped viruses that express CD4 receptors and CXCR4 co-receptor...

pmc.ncbi.nlm.nih.gov

Excitement plus!! The full program is online for the upcoming GRC Salmonella Biology and Pathogenesis meeting. There is still some room in the schedule for short talks, which will be chosen from submitted abstracts. Submit your abstract, if you haven't done so already. www.grc.org/salmonella-b...

kermit the frog from the muppet show is standing in front of a red curtain .

ALT: kermit the frog from the muppet show is standing in front of a red curtain .

media.tenor.com

Federal funding of biomedical research has been a remarkably successful partnership, with benefits that are so intertwined in our daily lives that they can be easy to take for granted. So what will we lose if the U.S. continues to defund research? theconversation.com/cuts-to-scie...

Cuts to science research funding cut American lives short − federal support is essential for medical breakthroughs

The National Institutes of Health has been integral to scientific progress in treating countless human diseases. Without its support, patients will ultimately pay the price.

theconversation.com

Thank you to Adair Borges @adairb.bsky.social for giving a great talk about her exciting science at @arcadiascience.com and for discussing careers in biotech with our trainees!

New research from the @jnpruneda.bsky.social and @michaelnadbio.bsky.social labs: In this collaborative work, the groups show that ubiquitin is directly linked to mono-ADP-ribose modifications on proteins, a process called “MARUbylation". www.embopress.org/doi/full/10....

Ubiquitin is directly linked via an ester to protein-conjugated mono-ADP-ribose | The EMBO Journal

imageimageCertain E3 ligases have been found to ubiquitylate hydroxyl groups on free NAD+ and ADP-ribose in vitro, but the in vivo occurrence of this dual post-translational modification has remained ...

embopress.org

New publication out of the @rauchlab.bsky.social at OHSU MMI

Journal of Experimental Medicine@jem.org · last yr.

First authors Madeline Churchill and Ankit Pandeya @nkeet50.bsky.social from @rauchlab.bsky.social show that tuft cells, known for their role in anti-parasite defenses, can also contribute to anti-bacterial responses in the small intestine. rupress.org/jem/article/... #InfectiousDisease

@laurenrodda.bsky.social, @nicelab.bsky.social , @jnpruneda.bsky.social and I wrote an OpEd on the impacts of NIH cuts on Oregon: www.bizjournals.com/portland/new... It was signed by over 450 OHSU researchers! It’s unfortunately paywalled, DM me if you’d like a gift link or a pdf of it.

Opinion: Scientists on how NIH cuts will hurt all Oregonians. - Portland Business Journal

"These cuts will cripple biomedical research and drug development in the U.S. We should be investing more in science, not less."

bizjournals.com

Come join us! No excuses!!!

Brittany Barker@brittanysbarker.bsky.social · last yr.

Only 1 week until the Stand Up For Science rally at the OR capitol! We'll be hearing from Rep. Andrea Salinas and at least 4 renowned scientists. Rally with me to defend science from censorship and cuts! Let's make this big! #sciencenotsilence #standupforscience2025 @standupforscience.bsky.social

NIH funding freeze stalls $1.5 billion in medical research grant funding : Shots - Health News www.npr.org/sections/sho...

NIH funding freeze stalls applications on $1.5 billion in medical research funds

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

npr.org