Excited to announce I am starting as Professor of Immunology at the University of Manchester this week! I am #hiring a #postdoc in Manchester, to work on human intestinal lymphocytes in #Coeliac disease, please get in touch if interested. @lydiabeckeriii.bsky.social

Camp Summer2023: We're Hiring

ALT: Camp Summer2023: We're Hiring

static.klipy.com

To understand what a lipid does, we need to know its partners. Which proteins bind lipids and how can we capture those interactions? Our new Nature Protocols paper provides a practical, step-by-step guide to identifying lipid-binding proteins. 🧵

🚨🚨 Faculty search! Spread the word! 🚨🚨 The Pathology, Microbiology, and Immunology Department at Vanderbilt is hiring! Special consideration will be given to faculty working with Risk Group 3 pathogens (so you can join us in our brand new state-of-the-art BSL3!) apply.interfolio.com/188545

Please repost! #microsky🦠 The Glickman Lab at MSK is recruiting! Projects in Mtb pathogenesis, basic biology of mycobacteria, and mycobacterial cancer therapies. See our publications here: tinyurl.com/3f386f4x Send CV and cover letter to: glickmanmycolab@gmail.com

What if we could design proteins to precisely control cell behavior? I’m thrilled to share our latest work, led by @kinasekid.bsky.social, @sauravk05.bsky.social, Mia Donald-Paladino, and Dongyang Li, developing de novo miniproteins that activate or inhibit kinases. www.biorxiv.org/content/10.6...

De novo design of selective kinase modulators

Protein kinases are critical regulators of cellular signaling, but precise modulation of their activity remains challenging due to their high structural conservation. Here, we present de novo designed...

biorxiv.org

Amazing week of science & camaraderie at GRC Microbial Toxins & Pathogenicity! Many thanks to chair @torreslab.bsky.social & the discussion leaders, speakers, poster presenters, attendees, & staff for an awesome meeting! Excited to organize the next one with new vice-chair @sauerlab.bsky.social!

🚨New preprint!🚨 Lack of specific affinity reagents hinders studies of signalling mechanisms. We show that sdAbs provide a robust scaffold for making linkage-specific ubiquitin binders, exemplified by 2A6, a versatile reagent for M1-linked ubiquitin chains. www.biorxiv.org/content/10.6...

I am thrilled to share our paper out in @cp-cell.bsky.social : "Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways." (1/4) www.cell.com/cell/fulltex...

Systematic discovery of pathogen effector functions across human pathogens and pathways

The eORFeome, a large-scale collection of open reading frames encoding viral proteins and secreted bacterial and parasite effectors, enables functional genomics across diverse pathways and pathogens. ...

cell.com

Our evil ORFeome paper is out! In collaboration with @alex-stark.bsky.social, we screened ~4,000 viral proteins and secreted effectors from bacteria and parasites, covering hundreds of diverse pathogens, for phenotypes in human cells.

Faculty search announcement 2026: Tenure-Track Assistant Professor in Microbiology at UT Southwestern in Dallas. We seek candidates working in microbial pathogenesis (broadly defined). Come join our community! (1/5) www.utsouthwestern.edu/departments/...

Job alert!  We’re hiring a Postdoctoral Fellow to develop nanobody-based spatial biology approaches to study TB granulomas. Please help spread the word! @microbiologysociety.org @aai.org @ascbiology.bsky.social @ohsunews.bsky.social @embo.org

📢 We're hiring! The Department of Microbiology & Cell Biology at Montana State University is hiring an Assistant Professor of Microbiology. We welcome applicants working in microbial pathogenesis, immunology, genetics, microbial evolution, and related areas. Apply: jobs.montana.edu/postings/52009

I gave a workshop on AlphaFold & related programs @ the University of Utah. Part 1 covers protein structure prediction before/after AlphaFold & deep learning neural networks. Part 2 covers the math behind the scores. Part 3 covers PyMOL & the webservers. youtube.com/@rolanddunbr...

A lot of work, over many years, and we finally see the missing piece at the heart of type 3 export!

cryoEM papers@cryoempapers.bsky.social · 2mo ago

Structure of the proton-powered secretion motor at the heart of the bacterial flagellum www.biorxiv.org/content/10.64898/2026.06.13.732081v1 #cryoEM

I'm excited to share our recent working using forward genetics to identify virulence determinants in Rickettsia. Check it out! www.biorxiv.org/content/10.6...

A genetic screen identifies O-antigen as essential for Rickettsia parkeri survival in macrophages by protecting from inflammasomes and interferon-stimulated genes

Lipopolysaccharide (LPS) is highly immunostimulatory, yet it is evolutionarily conserved among many obligate intracellular bacteria for unknown reasons. We report a forward genetic screen to identify ...

biorxiv.org

Online Now: TRIM21 induces selective autophagy of viruses and bacteria Online now:

TRIM21 induces selective autophagy of viruses and bacteria

Rhinesmith et al. describe an intracellular antimicrobial mechanism called “antibody-directed xenophagy” (ADX). In ADX, the E3 ubiquitin ligase TRIM21 prevents infection by intercepting antibody-coated viruses/bacteria in the cytosol and orchestrating their destruction via selective autophagy. The authors hypothesize that ADX may be co-opted for targeted protein degradation.

dlvr.it

Dual-channel Cx46/50 gap junction assemblies in a shared lipid-nanodisc = lipid-mediated packing and a lipid site near the NT gating region that is absent from single channels. Plus a 1.8 Å open-state single-channel benchmark! #cryo-EM 🍩’s #NIH-funded-research www.biorxiv.org/content/10.6...

One week left to apply for two 3-year postdocs in the lab on molecular mechanisms of Burkholderia pathogenesis. Posts associated with Magdalen College. Our lab is based in the Dunn School of Pathology with amazing collaborators at Oxford and MORU magdalencareers.pinpointhq.com/postings/c90...

Calleva Centre Postdoctoral Researchers- The deadly enigma of melioidosis: Decoding the pathogenesis of Burkholderia pseudomallei.

Job Opening: Calleva Centre Postdoctoral Researchers- The deadly enigma of melioidosis: Decoding the pathogenesis of Burkholderia pseudomallei. at Magdalen College in Central Oxford.

magdalencareers.pinpointhq.com

Interested in microbiology, immunology, and host-pathogen interactions? Come work with us! Our department at OHSU is opening a search for a new tenure-track faculty position. See the job advertisement for details. Please share within your networks! www.nature.com/naturecareer...

Faculty Position in Molecular Microbiology and Immunology - Portland, Oregon job with Oregon Health & Science University (OHSU) - Molecular Microbiology and Immunology | 12858852

The Department of Molecular Microbiology and Immunology at OHSU invites applications for a tenure-track Assistant or Associate Professor position.

nature.com

Only a couple of days left to register for the UK Cellular Microbiology Network Meeting - we will have a great line up of speakers and poster presenters investigating various pathogens in cell-based, tissue and in vivo models.

Gunnar N. Schroeder@gunnarns.bsky.social · 4mo ago

Registration and abstract submission for the 2026 UK CellularMicrobiologyNetwork Meeting are now open! Exiting keynote speakers and opportunity for researchers from the UK, Ireland and beyond to share their work on host-pathogen interactions. June 22nd/23rd @WWIEM in Belfast. www.ukcellmicro.org

Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)! The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us! apply.interfolio.com/185622 Applications due 8/1.

10 days left to register for the 2026 EMBO ubiquitin conference! Join us in coastal Puglia, for a jam packed schedule on all things ubiquitin (and friends). Fantastic line up of speakers and an impressive amount of opportunities for ECRs and networking. meetings.embo.org/event/26-ubi...

Postdocs - if you want to work on killer yeasts - I am HIRING. uidaho.peopleadmin.com/postings/51451 CLOSING SOON!

Postdoctoral Fellow

The postdoctoral fellow will work in the lab of Paul Rowley to understand the basis of resistance to antifungal “killer” toxins produced by different species of fungi. This hire will use genetics, bio...

uidaho.peopleadmin.com

MMI faculty member Isabella Rauch @rauchlab.bsky.social gave the @globalimmuno.bsky.social seminar today. You can find the recording on youtube at urldefense.com/v3/__https:/...

Over the past 5 years, 50 structures of full-length HECT-type ligase constructs have been deposited in the PDB. What have we learned from these studies, and what key questions remain open? Check out our new review on this exciting and fast-moving field: www.jbc.org/article/S002...

HECT-type ubiquitin ligases: Emerging principles in the era of full-length structures

Ubiquitin coordinates a complex network of cellular pathways through covalent modification of substrates. Specificity in substrate recognition and modification choice is largely conferred by ubiquitin...

jbc.org

Cdc48/p97 nibbling on #ubiquitin! Cool single molecule analysis study by the Tans group (with us) out now. rdcu.be/firGK

Our paper is finally out! 🥳 If you want to know how a single Salmonella effector rewires the whole macrophage transcriptional landscape by hijacking one host transcription factor, check our latest research! Thanks to the @thurstonlab.bsky.social and @peterwshill.bsky.social labs for an amazing work!

Salmonella effector SteE reprograms the macrophage regulatory network to drive specific hyperactivation of STAT3 target genes

The ability of Salmonella Typhimurium to exploit macrophages as a niche for survival, replication, and dissemination is central to its pathogenesis. T…

sciencedirect.com

We’re hiring! Join the Weber Lab at the University of Iowa to study Chlamydia effector biology, centrosome regulation, vesicular trafficking, and innate immunity. Please share!

🚨Faculty job search: University of Illinois Chicago Micro & Immuno department is hiring! Open rank and open area within host-pathogen interactions. Apply by May 31 to join us in UI College of Medicine in the heart of Chicago! uic.csod.com/ux/ats/caree...

Hope you can join us for our 10th Next Generation Biophysics Symposium @mrclmb.ac.uk in September. We have a fantastic speaker line up: www3.mrc-lmb.cam.ac.uk/sites/nextge...