Riding for a cure: Pittsburgh cancer patients, doctors and families unite at 'Rush to Crush Cancer'
Riding for a cure: Pittsburgh cancer patients, doctors and families unite at 'Rush to Crush Cancer'
For Mike Michna, completing an intense 15-mile bike ride at UPMC Hillman Cancer Center’s annual Rush to Crush Cancer event wasn’t just a physical...
post-gazette.com
Don't miss the next #EMGS webinar "Oxidative DNA Damage and Repair: Impacts and Methods of Detection," presented by the EMGS DNA Repair SIG. 🧬 Register Today: emgs-us.org/event/OxiDNAWEB
🏨Get the best rate to attend the #EMGS2025 Annual Meeting by booking through our room block at the Hyatt Regency Rochester! #GenomicsConference #EMGS #RochesterNY Book Now: emgs-us.org/page/2025-ho...
🐦Register by May 31st for #EMGS2025 to take advantage of our Early Bird Registration prices! Regular Member: $525 Early Career Investigator Member: $300 Student Member: $200 Emeritus: $200 Register Here: emgs-us.org/page/2025-re...
DID YOU KNOW? The Strong National Museum of Play in Rochester has the world’s largest collection of toys and games! 🪀👾 Join us in Rochester for #EMGS2025! emgs-us.org/page/2025_EMGS
2025 EMGS Annual Meeting
Genomic Health Innovations, Perspectives, and Progress Bloom in the Flower City
emgs-us.org
Tomorrow we have another exciting thesis defense from the Freudenthal lab! This time it is our rock climbing, dessert loving, MD/PhD candidate Luis Cortez. 🥳DM for a zoom link if interested
I ❤️ this new paper on RAD52 at replication forks, just published @nature.com. Cryo-EM reveals a unique double-ring structure that blocks reversal of replication forks. www.nature.com/articles/s41...
The RAD52 double-ring remodels replication forks restricting fork reversal - Nature
A head-to-head double-ring complex of the human multifunctional DNA repair protein RAD52 mediates protection of stalled replication forks during replication stress, protecting them from reversal by SM...
nature.com
🔊Don't miss the next #EMGS webinar: An Applied Genetic Toxicology Career in the Pharmaceutical Industry with Zhanna Sobol on April 8, 2025 at 12:00 PM EST! Register Now: emgs-us.org/event/AGTCPI...
Excited to share our new pre-print. Direct, ensemble FRET assays developed by our lab reveal that assembly of Rad51 filaments at stalled replication sites via RPA/Rad51 exchange causes complete & irreversible PCNA unloading. Big implications for interplay between human DNA damage tolerance pathways
biorxiv.org
🐦The deadline for Early Bird Registration for #EMGS2025 has been extended to May 31, 2025! Register Here: emgs-us.org/page/2025-re...
Free webinar! Join our expert panel for a thought-provoking discussion on the critical role of fundamental research in driving innovation and breakthroughs in cancer science ✨ #KeepResearchCurious 📅 25 March 16:00 CET 🌍 Zoom us02web.zoom.us/webinar/regi...
The latest newsletter from the Sikora Lab and Front Range ILC is up! Features in this 'issue': - Quick info on 'indirect' costs for advocates - Info and registration link for our Spring '25 outreach event (on 4/11 - come join us!) - Tracy's story re: full body MRI for cancer screening #lobular
2025 Spring Event and Research News
us21.campaign-archive.com
By attacking science: We are less safe because science informs national security and medical care. We are less prosperous because science drives innovation and economic benefit. We are less free because science and democracy depend on the liberty to ask questions, and seek and share knowledge.
One more bioRxiv update (v3) on MDC1 and DNA repair dysfunction in #lobular breast cancer: www.biorxiv.org/content/10.1... We worked w @foundationmedicine.bsky.social to see whether ILC mutations manifest as repair 'loss of function', and tumor genomes say... nope :). The ILC phenotype is unique!
Co-regulator activity of Mediator of DNA Damage Checkpoint 1 (MDC1) is associated with DNA repair dysfunction and PARP inhibitor sensitivity in lobular carcinoma of the breast
Invasive lobular carcinoma of the breast (ILC) is typically estrogen receptor α (ER)-positive and presents with biomarkers of anti-estrogen sensitive disease, yet patients with ILC face particularly p...
biorxiv.org
🔊Get ready for a new #EMGS webinar: Lessons from AI: Predicting mutability in healthy human tissues on April 16, 2025 at 11:00 AM EST. Register Now: emgs-us.org/event/AILess...
🔥🔥🔥Deadline for your abstract submission today! Don't miss out on the most exciting conference on The Ageing Genome in 2025!
EMBL Events@events.embl.org · last yr.📣 The abstract submission deadline for #EESAgeing is fast approaching! If you're interested in investigating genomic changes during the ageing process, be sure to join the 2nd edition of this EMBO | EMBL Symposium 🕐🧬 The deadline is 18 March ➡️https://s.embl.org/ees25-05-bl
I have written to Sen McCormick about my concerns on the defunding of US science. I finally received a response! He is supportive of research & thinks the F&A rates should be returned to previously negotiated rates! Thanks to @audreydrotos.bsky.social & @laurenkreeger.bsky.social for talking to him!
Annika rightfully points out that though this is positive, this is going to SERIOUSLY burden an NIH staff that is actively being further depleted. Be nice to your SROs, POs, and GMSs, folks...
Annika Barber@annikabarber.bsky.social · last yr.Yay: Most postponed study sections have been rescheduled at this point. Yikes: To do this, CSR has scheduled *289* study sections from 03/24-05/16/2025. For comparison, there were only 96 study sections from 3/24-5/17/2024. And NIH still plans to RIF more staff. docs.google.com/spreadsheets...
📢NEW YORK STUDENTS: We are offering a Free Student Day for local students at the #EMGS2025 Annual Meeting in Rochester! Come attend sessions, connect with peers, and explore career opportunities - FREE! Just use the code STUDENT25DAY when you register! emgs-us.org/page/2025-re...
2025 Annual Meeting Registration - Environmental Mutagenesis and Genomics Society
*Single Day registrants receive access to one day of the scientific program. Single Day Registration does not include access to social programs unless these programs occur on the registered day.
emgs-us.org
EMGS celebrates Pi Day & Int’l Day of Mathematics on 3/14/25! We recognize the crucial role of math in environmental science & genomics research. Here’s to the power of numbers in advancing our field! #PiDay2025 #IDM2025
New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
forbes.com
Cancer knows no borders, and setbacks in one part of the world can have lasting consequences for #patients everywhere The #EACR, and all co-signing national #cancer societies & foundations, stand in solidarity and offer our full support to our friends and colleagues in the US #StandUpForScience 🧪
EACR Statement on Threats to Cancer Research | The European Association for Cancer Research
eacr.org
EACR - European Association for Cancer Research@helloeacr.bsky.social · last yr.The EACR stands against threats to cancer research. Protecting scientific research is vital for progress and and the development of new treatments. Read our full statement in support of our friends and colleagues in the US: eacr.org/statement-on...
Great crowd in Pittsburgh Standing Up for Science. Thanks to all of the other great speakers sharing their stories!
🧬DID YOU KNOW? Rochester is a foodie haven with the famous ‘Garbage Plate’—a local culinary delight you must try! Join us there for #EMGS2025! Register Now: emgs-us.org/event/2025EMGS #GenomicsConference #RochesterScience
Environmental Mutagenesis and Genomics Society
emgs-us.org
Safeguarding the future of biomedical science in the United States: Cell www.cell.com/cell/fulltex...
Safeguarding the future of biomedical science in the United States
NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical infrastructure supporting groundbreaking biomedical research in the United States. This policy jeopardizes Americ...
cell.com
📢TAKE ACTION: Want to comment on the implementation of a 15% rate for facilities and administration costs associated with NIH grants issued to institutions of higher education? FASEB has crafted a letter that you can customize and send to your US Senators and Representatives: t.co/mk934ez2hZ
https://www.faseb.org/partnerships-and-outreach/legislative-action-center
t.co
Environmental Mutagenesis and Genomics Society@emgsus.bsky.social · last yr.Contact your Senators and Representatives to voice your concerns about the unprecedented cuts to F&A costs! The Federation of American Societies for Experimental Biology (FASEB) has developed a letter that you can customize and send to your US Senators and Representatives. t.co/mk934ez2hZ
Happy #WomensHistoryMonth and #InternationalWomensDay from the #EMGS! Did you know #EMGS has a Special Interest Group for #Women in EMGS? Learn more here: emgs-us.org/page/wemgs Chaired by @i_miousse! #WomenInSTEM #WomenInScience
Women in the EMGS SIG - Environmental Mutagenesis and Genomics Society
The mission of the Women in EMGS (WEMGS) Special Interest Group (SIG) is to provide a forum for discussion on the specific challenges faced by women in our society, a place for EMGS members of any sex interested in this topic to meet and share with one another, and an organized effort to share our experiences and support each other. Women in all fields of science have encountered barriers due to both negative stereotypes leading to being dismissed more easily as scientists, as well as societal pressures to perform more uncompensated and unrecognized work both in the workplace and at home. For both sexes, expectations in science have been at odds with the fulfillment of responsibilities outside of work (e.g. caregiving) and the nurturing of healthy and meaningful human relationships.The main event sponsored by WEMGS is a luncheon at the annual EMGS meeting. This luncheon may feature, for example, an invited speaker or a group discussion. Relevant activities of this SIG may also include, but are not limited to, planning and sponsoring symposia, platform sessions, breakfast meetings, social events, and workshops for the EMGS Annual Meeting, and updating members about the latest news through the EMGS website and email forum. Overall, this SIG provides a platform for members from all sectors (academia, industry, and government agencies) to discuss issues of importance to the WEMGS members and provide support to each other.
emgs-us.org
A great pleasure to share our newest paper out this morning @cp-molcell.bsky.social. We show that damage to nascent RNAs should not be ignored, and under certain conditions, these can turn into DNA breaks. We call this phenomena RDIBs (RNA Damage Induced Breaks). www.cell.com/molecular-ce...
YTHDC1 cooperates with the THO complex to prevent RNA-damage-induced DNA breaks
Tsao et al. uncover a novel pathway for genotoxicity, termed RNA-damage-induced DNA breaks (RDIBs). The mechanism for preventing RDIBs is orchestrated by YTHDC1 along with the THO complex, which funct...
cell.com
Register and submit your abstract now: The ageing genome: from mechanisms to disease www.embl.org/about/info/c...
The ageing genome: from mechanisms to disease
embl.org
