Last week, I had the great honour of being formally admitted as a Fellow of the @royalsociety.org & signing its historic Charter Book. Deeply grateful for this recognition of our work. None of this would've been possible without many wonderful lab members, colleagues & collaborators. ✨

In Formation - 4 artists - one goal: Art & Science Vernissage 5.07 at 17h00 @Muffatwerk

Congratulations to our Postdoc @palmrinmoy.bsky.social on receiving the Helmholtz Munich Doctoral Researcher Award 2026 for his outstanding PhD research. We are proud to now have you in our Schuh lab. A well-deserved recognition! 🎉🌟 📷credits: @helmholtzmunich.bsky.social

I am deeply honored to have been elected as a Foreign Member of the @royalsociety.org. Very grateful to all members of the lab, past & present. Their curiosity & commitment to science shaped the work in countless ways. It's been a privilege to work with them. www.mpinat.mpg.de/5261989/pr_2...

Royal Society elects Melina Schuh as Fellow

Biochemist Melina Schuh elected Fellow of the Royal Society for groundbreaking research on egg cell development.

mpinat.mpg.de

Many congratulations to our PostDoc @palmrinmoy.bsky.social on receiving the Best Poster Award at the @events.embl.org Practical Course “Ultrastructure Expansion Microscopy: From Cells to Tissue” last month! 🎉👏 A great achievement — very well deserved!

Grateful to receive the Pearse Prize from the @royalmicrosoc.bsky.social. A big thank you to my amazing team and collaborators — this is truly a shared recognition. 🌟 www.rms.org.uk/resource/dr-...

Dr Melina Schuh to receive RMS Pearse Prize

rms.org.uk

Just out! 👀 for TFs that regulate TEs.Clara's work with @tamas-schauer.bsky.social @marliesoomen.bsky.social @palmrinmoy.bsky.social and bluesky-less lab members 🌎 identifies TBP as a regulator of specific ERVL class: MaLRs in 🐭embryos -as always -feedback welcome👍 link.springer.com/article/10.1...

Defended my PhD last week! It’s been an incredible journey filled with challenges and exciting science. I'm deeply grateful to everyone who was part of it -especially @metorrespadilla.bsky.social for taking me on this ride. #PhDone 🎓

#LeibnizPreis für exzellente Forschung in der #Epigenetik: Welche Mechanismen liegen der Zellplastizität und Reprogrammierung von Zellen zugrunde? An der Antwort, die zukünftig bei der Heilung von Organen helfen könnte, arbeitet Maria-Elena Torres-Padilla @metorrespadilla.bsky.social. Gratulation!

We’re proud to announce #OvoLabs, co-founded by Melina @schuhlab.bsky.social, Agata Zielinska, and Oleksandr Yagensky. Building on decades of meiosis research, Ovo Labs aims to pioneer novel therapies to overcome the challenges of age-related infertility.

MPI for Multidisciplinary Sciences@mpi-nat.bsky.social · last yr.

More hope for pregnancy: The start-up #OvoLabs develops drugs to improve egg quality & success of fertility treatments. For this, the company founded by Melina Schuh @schuhlab.bsky.social, Agata Zielinska, & Oleksandr Yagensky secures £4 million in start-up capital. www.mpinat.mpg.de/5006185/pr_2...

Now online! The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways

The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways

In vivo screening in mouse embryos provides insights into the functional interplay between chromatin and the nuclear envelope in the establishment of lamina-associated domains, the earliest feature of nuclear organization following fertilization.

dlvr.it

How DNA Self-Organizes in the Early Embryo 🧬 The new insights challenge the classical model of genome organization & could lead to new disease treatments. 👉 t1p.de/25q7l @metorrespadilla.bsky.social @palmrinmoy.bsky.social @epihmgu.bsky.social @lmumuenchen.bsky.social

Here is-🥳🥳😇 tremendous effort by @palmrinmoy.bsky.social brilliantly supported by @tamas-schauer.bsky.social &super help by federico,iliya,tsune,adam,@mamartirenom.bsky.social Very happy to see this come to fruition- Look forward to feedback from colleagues ! More 👉 www.cell.com/cell/fulltex...

How does the genome find its place in the 3D space of the nucleus after fertilization? Out now @cellcellpress.bsky.social: cell.com/cell/fulltext/… 👇 A thread 👇

In this study, Hermant et al. describe the evolution of the retrotransposon MERVL and its cis-regulatory transcription factor binding motifs, highlighting the phyloregulatory adaptation at play during early embryogenesis. Learn more here: ➡️ tinyurl.com/gd352270

🚨New paper alert! RIF1 as a key in vivo regulator of replication timing consolidation during early mammalian development. Another great collaborative effort from my time in the @metorrespadilla.bsky.social lab. Excited to see this one out!!

ME Torres-Padilla@metorrespadilla.bsky.social · last yr.

Paper Out👇🥳 thanks to ALL authors, Nakatani-san @tamas-schauer.bsky.social @palmrinmoy.bsky.social and bluesky-less RIF1 regulates Replication Timing in mouse embryos & (suprising) findings disentangling effects on transcription and LADs...lots to think about 🙄👍🤔 👉 www.cell.com/developmenta...

we've put a Review together 👇 Just came out at www.nature.com/articles/s41... hoping it is useful for those in the field but also for those not in the field who would like an overview on chromatin/epigenetics/replication/nuclear organisation in early embryos Enjoy :) - feedback welcome

#LeibnizPrize 2025: Celebrating Excellence!🎉 👏Yesterday, Prof. Maria-Elena Torres-Padilla officially received the Gottfried Wilhelm Leibniz Prize from the German Research Foundation (DFG)! 👉 t1p.de/s6uma 🎥Watch her portrait: t1p.de/a30vo @metorrespadilla.bsky.social @dfg.de #LeibnizPreis

Maria-Elena Torres-Padilla - Gottfried Wilhelm Leibniz-Preisträgerin 2025 im Portrait

Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

t1p.de

If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next. Our manuscript, just published in Nature, provides some answers! www.nature.com/articles/s41... @lmumuenchen.bsky.social @erc.europa.eu a.eu @nature.com

🚨New Paper Alert! Check the news about the sucessful research led by our Director at IES here: 👉 t1p.de/d87p5. Original paper at @genesdev.bsky.social: genesdev.cshlp.org/content/earl... Congrats to Clara Hermant, Michel Mourra-Diaz, @marliesoomen.bsky.social, Mrinmoy Pal & rest of authors!

Helmholtz Munich@helmholtzmunich.bsky.social · last yr.

SRF: A New Regulator of Retrotransposons and Early Embryonic Genes🧬 A team led by Prof. Maria-Elena Torres-Padilla, #HelmholtzMunich, has uncovered a key player in early embryonic development: SRF. 👉 t1p.de/d87p5 @metorrespadilla.bsky.social @epihmgu.bsky.social #EmbryonicDevelopment #Epigenetics

SRF: A New Regulator of Retrotransposons and Early Embryonic Genes🧬 A team led by Prof. Maria-Elena Torres-Padilla, #HelmholtzMunich, has uncovered a key player in early embryonic development: SRF. 👉 t1p.de/d87p5 @metorrespadilla.bsky.social @epihmgu.bsky.social #EmbryonicDevelopment #Epigenetics

Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex... A short thread to highlight some of our findings 🧵

✨ Excited to share my latest preprint on how H3K4 methylation promotes transcriptional memory from gametes to embryos across a transcriptionally silent window — crucial for proper zygotic genome activation and development. 🐸🧬✨ 📄 Check it out here:
doi.org/10.1101/2025... 👇 Highlights below

H3K4 methylation-promoted transcriptional memory ensures faithful zygotic genome activation and embryonic development

In the life of a vertebrate embryo, gene expression is initiated for the first time at zygotic genome activation (ZGA). Maternally expressed transcription factors present in the embryo are essential f...

doi.org

🚨New paper alert, at Cell Press! 🚀 Excited to share groundbreaking research from Helmholtz Munich led by @metorrespadilla.bsky.social; @marliesoomen.bsky.social & @diego-rt.bsky.social. They've uncovered ancient viral DNA's role in early embryonic development! 👉 Original paper: shorturl.at/D7eCz

An atlas of transcription initiation reveals regulatory principles of gene and transposable element expression in early mammalian development

Transcriptional activation of the embryonic genome (EGA) is a major developmental landmark enabling the embryo to become independent from maternal con…

shorturl.at

Helmholtz Munich@helmholtzmunich.bsky.social · 2y ago

Ancient Viral #DNA Shapes Early Embryo Development Researchers at #HelmholtzMunich & LMU have uncovered the critical role of transposable elements - ancient viral #DNA remnants - in early embryo development: t1p.de/pb7sc @metorrespadilla.bsky.social @marliesoomen.bsky.social @epihmgu.bsky.social