Patrick Phillips

@patrickphillips.bsky.social

Geneticist at University of Oregon @uoregon. Worms, C. elegans, aging, evolution, genetics, genomics, complex traits. Former provost and interim president. Lab: https://pages.uoregon.edu/pphil/ GScholar: https://scholar.google.com/citations?user=JbH6mVkAAA

I've been using Anthropic's Operon, which is now Claude Science, for a few hairy projects lately. The amount of problem solving it has to do just to get packages installed properly is pretty insane, but matches our general experience. Worth doing just on that basis alone.

In 2024, NIH published 756 funding announcements (NOFOs) In 2025, it published 120. In 2026, as of 3/15, it published 14. Scientific program staff can no longer steward their fields b/c every NOFO must be approved by political appointees in the NIH director’s office, the DHHS, & the OMB.

I Wrote Research Funding Announcements for NIH for 22 Years. This Year They’ve Published 14

How NIH went from 756 funding announcements to 14 in two years — and what it means for every disease that depends on federal research

elizabethginexi.substack.com

Encoding recent movement history with Wormtrails makes spatial differences in C. elegans behavior much easier to see. In this assay, worms not only avoid the hydrogen peroxide gradient on the left, but also move faster near it. 4/

The resolution of microscopes has increased over 10,000 fold over the last 200 years. It's allowed scientists to examine not only cells, but bacteria, then viruses, their protein structure, and, eventually, the individual atoms that comprise them.

showing how microscope resolution has improved more than 10,000× over the past 200 years. The horizontal axis shows year (1800s to 2025). The left vertical axis shows feature size, from 1 micrometer (small bacteria) down to 0.01 nanometers (atomic nuclear structure). The right vertical axis shows resolving power in inverse angstroms. A blue curve at the bottom represents light microscopy, limited by visible-light diffraction to about 200 nanometers. A tan curve rising sharply in the mid-20th century represents electron microscopy, reaching nanometer-scale resolution. A red region near 0.1 nanometers shows aberration-corrected electron microscopy surpassing the electron diffraction limit. A blue region at the top shows ptychography achieving the highest resolving power through overlapping diffraction patterns and computation. Dots label key scientists and institutions at milestones. Overall trend shows steady, then dramatic gains in resolution over time.

The Gibson lab at UVA is hiring a postdoc to study dispersal as a parasite avoidance mechanism. Apply by mid-January: https://uva.wd1.myworkdayjobs.com/UVAJobs/job/Charlottesville-VA/Research-Associate-in-Biology_R0078709. #postdoc

Research Associate in Biology

The Department of Biology at the University of Virginia invites applicants for a post-doctoral Research Associate position in the lab of Professor Amanda Gibson as part of an NSF-funded project. The Gibson lab is broadly interested in the evolution of avoidance versus resistance as modes of parasite defense. This project specifically tests the idea that host dispersal evolves as an escape in space from parasites, and it evaluates the downstream consequences of dispersal for the evolution of host resistance. The work makes use of the experimental tools and resources available for the model nematode C. elegans and its natural parasites. Associated projects entail evolve-and-resequencing, quantitative trait mapping, and field sampling with spatial analyses. The selected candidate will also mentor undergraduate students in independent research projects through a summer program for incoming transfer students. Find out more about the lab at https://coevolving.org. REQUIRED QUALIFICATIONS: o A PhD in Biology or a related field by the start date. PREFERRED QUALIFICATIONS: Demonstrated conceptual and technical strengths in host-parasite interactions, evolutionary ecology, evolutionary genetics, and/or dispersal biology Experience in basic lab and molecular work A strong background in experimental design, data analysis, and data management Excellent written and oral communication, demonstrated by a strong publication record, consistent with the candidate’s career stage, and presentations at conferences Demonstrated ambition, creativity, independence, and ability to work well with others Experience in and dedication to mentoring junior trainees APPLICATION PROCEDURE: Apply online https://jobs.virginia.edu/us and search for R0078709. Attach a cover letter outlining your qualifications and motivation for pursuing the position, curriculum vitae, and contact information for three individuals who can provide professional reference letters. In the cover letter, please address your fit with the qualifications above and your experience in mentoring undergraduates. Please note that multiple documents can be uploaded in the box. APPLICATION DEADLINE: Review of applications will begin on January 15, 2026. The University will perform background checks on all new hires prior to employment. Anticipated start date for this position is May, 2026, but the start date is flexible. This is a one-year appointment; however, appointment may be renewed for additional two, one-year increments, contingent upon available funding and satisfactory performance. For questions about the position, please contact Amanda Gibson, Associate Professor, at akg5nq@virginia.edu. For questions about the application process, please contact Richard Haverstrom, Academic Recruiter, at rkh6j@virginia.edu. For information on the benefits available to postdoctoral associates at UVA, visit postdoc.virginia.edu and hr.virginia.edu/benefits. The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Click here to read more about UVA’s commitment to non-discrimination and equal opportunity employment. PLEASE READ: The job postings for this page have been moved to a new location. Please visit the UVA Careers Websites to navigate to the appropriate site, or click UVA Careers in the upper right corner of this page to view open positions. If have already applied and need to log in to your existing Workday account, please click Sign In in the upper right corner of this page. Please do not sign in until you have visited and applied through a UVA Careers website.

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