Justin Blumenstiel

@bdelloid.bsky.social

Evolution, Genomics, Genetics, Epigenetics, Transposons, Small RNAs, Meiosis, Politics, Music, Kansas....AND DROSOPHILA!!! Freaked out ribosome and DNA truther doing my own research. "We are our own reviewers" - Alejandro Montenegro‬ ‪

Voters in Kansas saw through a blatant political power grab and sent a message — our courts are not for sale.

Blue graphic with text “Victory!  
 
 
Kansas voters showed up and protected their impartial state supreme court, helping defend abortion rights, LGBTQ rights, and civil liberties for generations to come.”

The same old Susan Collins charade. As soon as a controversial nominee or a bill has enough votes to pass, she announces she will vote no when it doesn’t matter. She never casts a deciding vote against Trump. Now she will claim this shows how she is so “independent.”

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What is driving these dynamics? Mutations? Niche signals? Something else? We don't know, but we speculate in the paper. Let us know if you have any ideas! There is plenty more in there too. All credit to co-first authors Jenna and Connor, and the rest of #TeamTestis. Thanks to NIGMS for support.

Wikipedia remains one of the most useful things online. No subscription fees, no ads, no stupid pursuit of AI, all curated by relentless nerds. Maybe remember to throw them a few bucks every now and again.

So, bluesky, where is the discussion of the absolute insane things AI is doing in the realm of mathematics? It seems like we're nearly at the inflection point where the models are as good as human domain experts, and soon may well be better. Is that discourse only happening on twitter?

All my Kansas peeps - Jerry Moran is a close friend of Thune. And I have sensed some skepticism of Vought from his office. TIME TO STRIKE WHILE THE IRON IS HOT! Call his office or send an email or even visit his office. I might do so Monday...

Colette Delawalla, PhD@cdelawalla.bsky.social · 5d ago

WHEN WE FIGHT, WE WIN. It's time to APPLY HEAVY PRESSURE. Call you Senators NOW: fight2win.standupforscience.net/campaign/omb... I know, everyone hates calling. But this is CRITICAL. Make the calls today! (Use our super easy autodialer tool linked above) www.politico.com/live-updates...

Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...

Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS

In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...

pnas.org

23andMe is hiring for 2 amazing roles! - Scientist, ML for Health Risk Prediction: build next-gen health prediction tools integrating genetics. - Scientist, Population Genetics: build state-of-the-art algorithms for genetic relationship & ancestry inference. Links below!

How do transposons jump when they’re released from host control? I babysat two chromosomes for 2 years, making sure they are ok without most piRNAs. Here’s what we found & excited to share my 1st postdoc paper: “piRNA loss unleashes episodic transposition bursts” www.biorxiv.org/content/10.6...

piRNA loss unleashes episodic transposition bursts

In Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon ex...

biorxiv.org