Now out in Cell @cellpress.bsky.social: Researchers in the @priscaliberali.bsky.social lab & collaborators at @istaresearch.bsky.social show how regenerating gut tissue turns small cellular differences into stable patterns, revealing a broader principle of tissue repair. www.fmi.ch/news-events/...

How the gut rebuilds order after injury

FMI researchers and their collaborators have shown how regenerating intestinal tissue turns small initial differences between cells into stable patterns. The findings reveal a general principle for ho...

fmi.ch

It is out 😍 check it out!! Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning. @cschwayer.bsky.social @silviabarbiero.bsky.social @davidbrueckner.bsky.social @ehannezo.bsky.social www.cell.com/cell/fulltex...

Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning

During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...

cell.com

Our seminar room was almost overflowing for the third Friedrich Miescher Lecture, hosted by @priscaliberali.bsky.social and delivered by Ewa Paluch from @cam.ac.uk. Paluch gave a fascinating talk on cell shape and the cross-talk between cell shape and cell fate 🔬🧫

Emergence and Self-organisation across biological scales! I hope you are ready for next year conference! It will be an incredible event April 20-22 2026. The first of many #LakeConference organised by @ehannezo.bsky.social @alleninstitute.org and James Sharpe @embl.org

allen institute@alleninstitute.org · 9mo ago

#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel! 📆 April 20-22, 2026 📍 Seattle, USA 🔬 All career stages welcomed. Apply to attend by 12/12: alleninstitute.org/events/aics-...

The last day of lectures at #LISH25 starts with Gustavo Medeiros presenting applications of light sheet microscopy to #organoid research. @priscaliberali.bsky.social lab. Gustavo is a physicist and a creative artist and the walk-up song delivers that message. Video in thread.

🚨We're hiring! Join a global team at the @priscaliberali.bsky.social lab & the @alleninstitute.org to build cutting-edge image analysis workflows for complex biological datasets, including light-sheet microscopy images. Apply at: www.fmi.ch/education-ca...

We're seeking a Research Associate in stem cell biology to join a global, interdisciplinary team investigating organoids and tissue organization. This unique role is part of a collaboration between the @priscaliberali.bsky.social lab & the @alleninstitute.org. Apply at: www.fmi.ch/education-ca...

In @naturephysics.bsky.social, researchers from @priscaliberali.bsky.social's lab and @ehannezo.bsky.social's group reveal how intestinal organoids form crypts, key to gut regeneration and stability. Their work could impact tissue engineering and regenerative medicine. www.fmi.ch/news-events/...

Shaping the gut: how tissue mechanics drives intestinal organoids formation

FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut regeneration and long-term stability. Their findings may have broader implications fo...

fmi.ch

Amazing work Irene and Tomo!

Irene Miguel-Aliaga@irenemiguel-aliaga.bsky.social · last yr.

Epic effort led by Tomo Ameku in the lab, with contributions from the labs of Nick Bellono, Vassilis Pachnis, @francoisleulier.bsky.social, @schwarzergnoto.bsky.social, @priscaliberali.bsky.social, ‪@coxlabkcl.bsky.social,‬ @priscaliberali.bsky.social and Maria Rodriguez-Colman

Super retreat! And don’t miss the paper on robustness in crypt morphogenesis 🤩

Edouard Hannezo@ehannezo.bsky.social · last yr.

Fun group retreat in the Austrian alps with @priscaliberali.bsky.social! And perfect time to celebrate our new joint paper (from Shi-Lei Xue & Qiutan Yang) out on how mechanochemical bistability confers robustness to intestinal organoids! www.nature.com/articles/s41... - see 🧵! (1/n)

Fun group retreat in the Austrian alps with @priscaliberali.bsky.social! And perfect time to celebrate our new joint paper (from Shi-Lei Xue & Qiutan Yang) out on how mechanochemical bistability confers robustness to intestinal organoids! www.nature.com/articles/s41... - see 🧵! (1/n)

Don’t forget to apply! This is an amazing opportunity!

FMI science@fmiscience.bsky.social · 2y ago

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

A perfect start in the new year! 🌱 Regenerating tissues are just an amazing spatio temporal controlled process! Our new manuscript explores how cell heterogeneity and bistability orchestrate intestinal regeneration. 🧵 biorxiv.org/cgi/content/...

Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration

Tissue regeneration relies on the ability of cells to undergo de novo patterning. While tissue patterning has been viewed as the transition from initially identical un-patterned cells to an arrangemen...

biorxiv.org

Join us at FMI as a Junior Group Leader! A unique opportunity to set up your lab in a vibrant international research institute with world-class research groups and facilities, generous core funding, a collegial and inclusive culture - and great colleagues 🤓!

FMI science@fmiscience.bsky.social · 2y ago

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

We have a new opening! Amazing environment colleagues and facility! Join us!

FMI science@fmiscience.bsky.social · 2y ago

📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...

Do you want to know how tissue is coordinated across space and time? Don’t miss Laura’s talk!

@lauracapolupo.bsky.social · 2y ago

If you are attending #CellBio2024 and are interested in understanding how the process of crypt morphogenesis is coordinated both in vivo and in organoids then come to my talk Wed Dec 18th in the subgroup “Organoids as tools to study the function of tissue in Health and Disease”

Don’t miss Conny’s talk!!

Cornelia Schwayer@cschwayer.bsky.social · 2y ago

Have you ever wondered how cell heterogeneity can regulate tissue patterning and how such patterns are maintained? Then come to my talk at the ASCB meeting #cellbio2024 this Sunday afternoon ☺️

My first post here to celebrate the lab and their achievements. What a fantastic night!

FMI science@fmiscience.bsky.social · 2y ago

In recognition of her groundbreaking research at the FMI, our very own @priscaliberali.bsky.social was awarded the Basel City Science Prize last night by Lukas Engelberger, Conradin Cramer, Mustafa Atici with FMI Director Dirk Schübeler and group leader Margherita Turco in attendance! bit.ly/3ZbiPnB