Keeping a keen eye on the therapeutic potential of rapamycin-an immunomodulator 1st approved as a prophylactic against organ rejection. Two new pilots show that: 1) it didn’t penetrate the BBB but improved inflammatory biomarkers and 2) fatigue, cognition in #MECFS www.nature.com/articles/s43...

Rapamycin treatment for Alzheimer’s disease and related dementias: a pilot phase 1 clinical trial - Communications Medicine

Gonzales et al. conducted an open-label phase 1 clinical trial of rapamycin for mild cognitive impairment and dementia due to Alzheimer’s disease. Rapamycin is not detected in cerebrospinal fluid befo...

nature.com

🚨 NEW RESEARCH! ⚕️ 🩺 DeLong et al. find associations between physical #multimorbidity and #depression using the UKBiobank data. https://bit.ly/4kz23rD #MentalHealth #PhysicalHealth

Cluster and survival analysis of UK biobank data reveals associations between physical multimorbidity clusters and subsequent depression - Communications Medicine

DeLong et al. investigate several clustering techniques to identify patterns of physical multimorbidity. They find several clusters which align to known body systems and use survival analyses to determine which clusters are most associated with depression.

bit.ly

Amazing! I’ll be printing this out and taking with me to all appointments

Bateman Horne Center@batemanhornecenter.bsky.social · last yr.

The Clinical Care Guide for #MECFS, #LongCOVID & IACCs is here! Download, share, and use it to support better care. BHC's approach is now freely available—designed to help providers manage complex conditions with clarity & compassion. Download it. Share it. Use it. bit.ly/432YdzF

A housing project specifically for people with severe ME/CFS, including 24-hour assistance, is being planned in Neunkirchen-Seelscheid Info in German sozialhummel.de/wohnprojekt-... Some info & discussion in English www.s4me.info/threads/hous... Image from Science for ME update #MEcfs #SevereME

Daisy having the best day ever, scoring a slice of pepperoni on her walk 🍕

NIH observational study finds that one of every 22 covid infections causes myalgic encephelomyelitis: www.livescience.com/health/coron...

1 in 22 COVID survivors develop debilitating chronic syndrome

A study suggests that catching COVID-19 significantly raises the risk of developing ME/CFS (formerly called "chronic fatigue syndrome"), a typically lifelong condition that can be debilitating.

livescience.com

My favorite from today. #HandsOff #HandsOff2025

This whole conversation about #LongCovid... Research published in Nature Medicine estimates Long Covid has an annual economic impact of approximately $1 trillion—equivalent to about 1% of the global economy. www.nature.com/articles/s41...

Thanks the Age for handing my story with care and Congrats Dr Armstrong & team on this exciting finding. This research isn’t possible without Open Medicine Foundation funding #MECFS research where NHMRC won’t. Newspaper👇 www.theage.com.au/national/vic... Research👇 www.nature.com/articles/s43...

It took 11 years for Adrienne’s illness to be diagnosed. A new computer model could change everything

Chronic fatigue syndrome is notoriously difficult to diagnose, but a new computer-assisted model can predict it with 85 per cent accuracy.

theage.com.au

99.4% of new drugs approved by the FDA are the product of NIH funded research. Remember this every time you see another headline on the NIH funding cuts. It will directly impact YOU. #ScienceNOTSilence

#LongCovidAwarenessDay2025

Forest therapy 😍🌺🐨🌈

“My average (long COVID) patient is previously very fit, very successful, and desperate to get back to normal life,” he says. “The people I’m looking at are actually incredibly motivated, the movers and shakers of society, and we lose them to our detriment.” 😭😭💔💔

The Guardian@theguardian.com · 2y ago

‘We’re losing decades of our life to this illness’: long Covid patients on the fear of being forgotten

My friends are dying. People are dying of #LongCovid and #MECFS while society keeps ignoring their existence. Rest in peace, Faraz. Sorry we failed you.

Dr. Sabine Hermisson 🦋@sabinehermisson.bsky.social · 2y ago

🖤🕯️ Faraz Fallahi Mein Mitgefühl: Mit Faraz' Familie und allen, die um ihn trauern. Mit allen, die schwer krank sind und um ihr Leben kämpfen. Mit allen, die unter dem dramatischen Mangel an medizinischer Versorgung, Forschung und Therapien zu #MECFS leiden.

New to behavioural mental health trials and unsure how to assess and monitor harms? With MAGNET Clinical Trial Network, we have developed a “How To” guide with step by step recommendations & tips. We hope you find it helpful! #behaviouralscience #behavioralmedicine doi.org/10.1177/0004...

Last night’s Australian Story following the lives of two people who lost their spouse to sudden cardiac arrest was so powerful. A reminder of the importance of the work we do in CVD research www.abc.net.au/news/2025-02... #suddencardiacarrest #cpr #cardiac

Heartfelt | Col Clausen + Laura Aisbett

Follow the latest news headlines from Australia's most trusted source. Read in-depth expert analysis and watch live coverage on ABC News.

abc.net.au

Great paper Sarah! #behaviouralscience #nutrition #cardiovasculardisease

Dr Sarah Gauci@sarahgauci.bsky.social · 2y ago

New Research: Psychosocial & nutritional support is vital in cardiac rehab—but gaps exist in delivery 🔍 98 practitioners surveyed 📊 Screening not consistent 🍽️ Expert dietary support lacking How can we better support practitioners to close these gaps? www.sciencedirect.com/science/arti...

The irony of the richest man in the world almost single-handedly destroying an agency designed to help the world’s poor, so that the U.S. federal budget has more room for another giant tax cut for the richest man in the world and his pals, should not be lost on anyone. [Cartoon by Mike Luckovich]

More information on negative responses to Cochrane scrapping their plan to do a new review of exercise therapy for CFS Links: thesicktimes.org/2025/02/04/r... www.s4me.info/threads/s4me... Screenshot from latest Science for ME weekly update #MEcfs #CFS

Thank goodness for the American Medical Association. Here is their YouTube page. Please share far and wide. Right now bird flu is spreading throughout our country and most people have no clue. Please stay updated and bookmark this page for your health and well-being. www.youtube.com/@americanmed...

NIH doesn’t just support infectious disease research—it drives breakthroughs in cancer, childhood diseases, heart disease, diabetes & more. Thanks to NIH, we have: 💉 Cancer immunotherapy ❤️ Cholesterol-lowering statins 🩸 Insulin for diabetes Investing in NIH = investing in life-saving discoveries.

My veggie garden is going gangbusters! 🍎🍆🎃🍅

Summer sunset in Victoria, Australia after crazy storms last night

Some NIH study sections for tomorrow have just been canceled. Who knows which of these grants would have led to the next life-saving invention. Who knows which scientists will throw in the towel bc of funding delays. Who can even begin to measure the impact of these reckless cancellations.😕🩺🧪🛟

This is a super scary - both for scientists relying on NIH funds and for patients awaiting scientific advances in treatments 😭

Jeremy Yoder says no war@jbyoder.org · 2y ago

Reiterating my call to fellow federally-funded scientists: Call your reps, tell them how this hurts science and everything good that comes from science (Also non-scientists, and scientists without federal funding! But the more of us who can directly speak to the impacts of these freezes the better)

Not to mention the harm this paper has done in the time since it was published by concluding LC is strikingly rare in kids when they seemingly did not even understand what LC is. 😫

Mark Ungrin@mark-ungrin.bsky.social · 2y ago

🧵An example of the shenanigans and junk science accepted in medical journals. In September 2023, JAMA Pediatrics published a ludicrously bad paper (quasi-retracted after much effort) claiming long COVID is "strikingly rare" in kids, supposedly vs the WHO definition. jamanetwork.com/journals/jam...

Here’s a summary of our recent CALM trial results showing lifestyle counselling with dietitians/EPs was non inferior to psychotherapy with psychs for low grade depression published in Lancet Regional Health. Thanks to Dr Deb Ashtree for the infographic! #lifestylepsychiatry #behaviouralscience

😭😭😭😭

Prof. Michael Fuhrer@michaelsfuhrer.bsky.social · 2y ago

Quite an opening paragraph in this story: "Among the current generation of kids, many are growing up with their mother or father confined to bed or confined to bed themselves. According to a study by ANU, long COVID is hitting up to an estimated 20% of Australians three months after...COVID..." 1/

Interesting trial of behavioural text messages for uptake of CVD medication refills in JAMA today Generic refill reminders; behavioral nudge refill reminders; nudge refill reminders + fixed-message chatbot did not differ from usual care #behavioralscience jamanetwork.com/journals/jam...

Message Reminders to Improve Adherence to Chronic Cardiovascular Medications

This randomized clinical trial compares different text messaging strategies (generic refill reminders, behavioral nudge refill reminders, behavioral nudge refill reminders plus a fixed-message chatbot...

jamanetwork.com

Grateful to Medical Journal of Australia Insight + mag for featuring this piece on the role of dietitians & exercise physiologists in managing mental health and our current opportunity for GPs to refer their patients to our national trial #behavioralscience insightplus.mja.com.au/2024/47/can-...

Can treating depression mitigate the excess cardiometabolic risk of people living with serious mental illness?

A national primary-care based trial is the largest ever to determine whether lifestyle therapy is

insightplus.mja.com.au