Congrats to Shijin, Drew, and Martin on publication of this C-H arylation with remarkable terminal selectivity! 3,5-lutidine turns out to be key! Check it out in Chem Eur J @chemistryeurope.bsky.social chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...

Terminal Selective Arylation of Inert Alkanes via Radical‐Organometallic Crossover

Selectivity is an essential part of organic synthesis and key to synthetic efficiency. However, selectivity is challenging to achieve in hydrocarbon molecules. Herein we report a mild and direct meth....

chemistry-europe.onlinelibrary.wiley.com

Excited to share this new paper in @natcomms.nature.com co-led by Harry Bian and Shijin Yu on photocatalytic azidofunctionalizations using iron terpy complexes. Iron LMCT in the visible range! www.nature.com/articles/s41...

Photocatalytic anti-Markovnikov hydro- and haloazidation of alkenes - Nature Communications

Hydroazidation of alkenes provides a direct entry to alkyl azides which are prevalent structural motifs in medicine development and chemical biology probes. Here the authors report a photocatalytic an...

nature.com

Really excited to share this collaboration with the Katayev group @unibe.ch showing how Fe/S catalysis can make privileged bioisosteres quickly, easily, and cheaply! Check it out in @angewandtechemie.bsky.social onlinelibrary.wiley.com/doi/10.1002/...

Overcoming Challenges in Small‐Ring Transfer: Direct Decarboxylative Hydroalkylation of Alkenes via Iron‐Thiol Catalysis

Cyclopropanes, especially those substituted with trifluoromethyl (CF3) groups, are valuable scaffolds in medicinal chemistry. Their enhanced bioavailability contributes to the widespread presence of ....

onlinelibrary.wiley.com

Movie you’ve watched more than six times using gifs. (“Hard mode” no Star Wars, Star Trek, or LOTR)

a bunch of cartoon characters with stars on their heads

ALT: a bunch of cartoon characters with stars on their heads

media.tenor.com

Well-tarred Flask 🇮🇹🇺🇦🇨🇦@chemprofcramer.bsky.social · last yr.

Movie you’ve watched more than six times using gifs. (“Hard mode” no Star Wars, Star Trek, or LOTR)

PhD Timeline xkcd.com/3081

Congrats @austinjacious.bsky.social, Paige Sutter, Alex Chavez, and Sebastian Cruz on publishing this cool study on alkene hydroalkylation using TBADT/thiol catalysis! A brand new project area started and led by Austin! #realtimechem pubs.acs.org/doi/10.1021/...

Mild Hydroalkylation of Terminal Olefins Via Decatungstate/Thiol Cooperative Photocatalysis

Here we report the use of a tetrabutylammonium decatungstate (TBADT)/thiol photocatalytic system for selective addition of acetone and other simple ketone, nitrile, and chlorocarbon functionalities to terminal olefins. This system avoids the use of energetic reagents such as peroxides and proceeds under mild conditions using Earth-abundant element catalysts, providing a sustainable approach to C–C bond formation using activated olefins. Initial exploration reveals that hydroalkylation of unactivated olefins is also possible, though in lower efficiency, and preliminary mechanistic experiments are consistent with a radical mechanism.

pubs.acs.org

Congratulations also to DOCTOR @austinjacious.bsky.social for defending his innovative thesis on Monday as part of the West Lab double-header!! So excited for the great things he'll do beyond Rice!

Sarah Buzsaki@sbuzsaki.bsky.social · last yr.

Nothing could be more fitting than defending on the same day as Austin (@austinjacious.bsky.social), my forever Rice cohort twin. We will continue to point out it was not intentional (which is true!) but it is quite thematically appropriate regardless. :')

Enormous congratulations DOCTOR @sbuzsaki.bsky.social!!! What a fantastic defense to wrap up a truly pathbreaking PhD and I am so glad I could celebrate with you yesterday! It has been a true privilege to work with you and I look forward to supporting you in the years to come!

Sarah Buzsaki@sbuzsaki.bsky.social · last yr.

#PhDone !!! Very happy to say that (yesterday) I successfully defended my thesis after five years at Rice University working with @pushingarrows.bsky.social to become Dr. Buzsaki! Thank you to everyone who was there, in person, on zoom, or in spirit. ❤️

As a small piece of science news, it was great to see our report on iron photocatalyzed diazidation, dichlorination, and fluorochlorination featured in the 2024 @chemicalscience.rsc.org most popular organic chemistry papers collection! Paper here: pubs.rsc.org/en/content/a...

Photocatalytic, modular difunctionalization of alkenes enabled by ligand-to-metal charge transfer and radical ligand transfer

Ligand-to-metal charge transfer (LMCT) is a mechanistic strategy that provides a powerful tool to access diverse open-shell species using earth abundant elements and has seen tremendous growth in rece...

pubs.rsc.org

Chemical Science@chemicalscience.rsc.org · last yr.

We are pleased to announce that our 2024 most popular article collections are now online! Check out the links below for the most popular articles from last year in your field: Analytical Chemistry pubs.rsc.org/en/jour... Catalysis pubs.rsc.org/en/jour...

Age yourself with a cartoon you watched as a kid

a close up of a person wearing a red hat with the words singing i want to be the very best

Alt: a close up of a person wearing a red hat with the words singing i want to be the very best

media.tenor.com

Dave Palmer@davepalmerusask.bsky.social · last yr.

Age yourself with a cartoon you watched as a kid

Excited (and nervous) to say that as of today, I'm a month away from my thesis defense! If you're not at Rice and interested in virtually attending, please fill out this google form :) docs.google.com/forms/d/e/1F...

Sarah Buzsaki Thesis Defense

For those outside of Rice University, please fill out the details below if you're interested in virtually attending my thesis defense! :) I'll send you an email with the Zoom link, and (hopefully) a r...

docs.google.com

Share with US students who had their offers of admission withdrawn for PhD programs: Apply to Canada. Check out Canadian professors, and contact us. Our system works differently here, and we are all still, technically, able to accept students for Fall 2025.

No matter what you think of the Israel/Palestine situation, and no matter what you think of the Columbia Univ. protests: If ICE can grab a permanent resident, suddenly revoke their Green Card (!) and whisk them away to a distant prison incommunicado, no one’s liberties are really safe.

Coach Finstock@coachfinstock.bsky.social · last yr.

Uses the word "proudly" in the first sentence. Says it is the "first arrest of many to come" in the second sentence. If you think this ends with "Hamas Students" you are not paying attention

Movies you've watched more than six times, gifs only

a girl is sitting on a red couch next to a man with a no face mask

Alt: a girl is sitting on a red couch next to a man with a no face mask in spirited away

media.tenor.com

Scott Bagley@bagphos.bsky.social · 2y ago

Movies you've watched more than six times, gifs only

As FDA regulations are "revisited" and countless reviewers are fired, it's worth reviewing why we built up the modern FDA in the first place (spoiler alert: preventable national tragedy). www.theatlantic.com/technology/a...

The Accidental Poison That Founded the Modern FDA

Elixir Sulfanilamide was a breakthrough antibiotic—until it killed more than 100 people.

theatlantic.com

Excited to share our latest work on photoactive surfactants for photocatalysis in aqueous solution. Congratulations to Ying Chen for a great paper! #PhotoactiveSurfactants #Photocatalysis

Delighted to contribute some thoughts to this wonderful article in @chemistryworld.com by Rachel Brazil on putting fluorine in drug molecules along with @tnoel82.bsky.social , Veronique Gouverneur, David O'Hagan, and Rob Young! Check it out! #realtimechem www.chemistryworld.com/features/put...

Putting the F in pharma

Adding fluorine to drug molecules can be tricky, but is often worthwhile. Rachel Brazil talks to the chemists trying to tame the ninth element

chemistryworld.com

In your opinion, what’s a cover version of a song that not only holds up to the original but wildly exceeds it? Here's mine (not too deep a cut, admittedly): music.youtube.com/watch?v=gSS2...

Hurt

YouTube video by Johnny Cash - Topic

music.youtube.com

Alex Knapp@thealexknapp.bsky.social · 2y ago

In your opinion, what’s a cover version of a song that not only holds up to the original but wildly exceeds it? Here's mine: www.youtube.com/watch?v=gooI...

Excited for this collaborative paper on nanoscale photoreactors to finally be out in #ChemSci @roysocchem.bsky.social! Check it out! pubs.rsc.org/en/content/a...

Supramolecular self-assembly of metal complex surfactants (MeCS) into micellar nanoscale reactors in aqueous solution

Surfactants are amphiphilic molecules that can form micellar structures with a hydrophobic core and a hydrophilic corona in water. In this work, we combine the remarkable properties of photoactive met...

pubs.rsc.org

Thrilled to welcome our newest postdoc, Shih-Chieh Kao, who joins us after his PhD in the West group at Rice. Looking forward to all the exciting chemistry you will do over the next few years. @pushingarrows.bsky.social @oxfordchemistry.bsky.social

This is also true about running a research group

priscilla page@priscillapage.bsky.social · 2y ago

once again thinking about this passage from David Lynch's book Catching the Big Fish

🚨Coming up today at 12 noon ET🚨 Join us for today's @organicdivision.org Virtual Symposium Watch for free: YouTube: orgn.link/watch Zoom: orgn.link/vs-zoom Thank you to @BeyondCCHF #ChemSky

Scott Bagley@bagphos.bsky.social · 2y ago

Save the Date!! The first ACS-DOC @organicdivision.org Virtual Symposium of 2025 is on January 15, 2025 @ 12 noon ET featuring Yang Yang & Julian West @pushingarrows.bsky.social Watch for free at: YouTube: orgn.link/watch Zoom: orgn.link/vs-zoom Thank you to @BeyondCCHF for hosting #ChemSky

What a fantastic surprise to see our new photocatalytic hydrochlorination featured by @thealexknapp.bsky.social in The Prototype @forbes.com!! We hope the reaction will help revolutionize discovery and manufacturing of important molecules for modern life!

Alex Knapp@thealexknapp.bsky.social · 2y ago

The latest edition of The Prototype is now live! Here's what's inside: 🚀 2024 had a record number of rocket launches 💻 A startup building CMOS transistors optimized for quantum computers 🧪 A sustainable way to make chlorinated industrial chemicals Plus much more!

Cool paper from a team led by @pushingarrows.bsky.social (a Forbes 30 Under 30 alum) at Rice: they figured out a way to chlorinate organic compounds with blue light and catalysts at room temperatures. This has interesting potential for pharmaceutical manufacturing. www.nature.com/articles/s44...

Anti-Markovnikov hydro- and deuterochlorination of unsaturated hydrocarbons using iron photocatalysis - Nature Synthesis

Methods for the anti-Markovnikov-selective hydrochlorination of unsaturated C–C bonds are limited by the need for stoichiometric reagents, highly oxidizing photocatalysts and multiple synthetic steps....

nature.com

Traditionally, chemists have had to resort to harsh conditions, pricey reagents, or multiple synthetic steps to manage anti-Markovnikov hydrochlorination. Researchers have now devised a new way to do it with inexpensive catalysts and mild conditions. cen.acs.org/synthesis/ca... #chemsky🧪 #scinews

A simple solution to a chlorination challenge

Iron-catalyzed reaction functionalizes less-favored positions with less fuss

cen.acs.org

Check out this great article by @bribarbu.bsky.social in @cenmag.bsky.social on our hydrochlorination! Bri has an unmatched talent for summarizing chemistry in ways that are accessible, interesting, and make you want to keep reading more!

Bri Barbu@bribarbu.bsky.social · 2y ago

My first story of 2025--a news item about some neat iron-based photochemistry from @pushingarrows.bsky.social that I've had in the hopper since December--has now been released into the world! Many thanks to @laurahowes.bsky.social for stepping in to edit me this week! cen.acs.org/synthesis/ca...

My first story of 2025--a news item about some neat iron-based photochemistry from @pushingarrows.bsky.social that I've had in the hopper since December--has now been released into the world! Many thanks to @laurahowes.bsky.social for stepping in to edit me this week! cen.acs.org/synthesis/ca...

A simple solution to a chlorination challenge

Iron-catalyzed reaction functionalizes less-favored positions with less fuss

cen.acs.org

Now online: Article by Kang-Jie Bian, @pushingarrows.bsky.social & co-workers Anti-Markovnikov hydro- and deuterochlorination of unsaturated hydrocarbons using iron photocatalysis www.nature.com/articles/s44... ($) #chemsky

Anti-Markovnikov hydro- and deuterochlorination of unsaturated hydrocarbons using iron photocatalysis - Nature Synthesis

Methods for the anti-Markovnikov-selective hydrochlorination of unsaturated C–C bonds are limited by the need for stoichiometric reagents, highly oxidizing photocatalysts and multiple synthetic steps....

nature.com

Excited to start the new year with this new method for photocatalytic hydro- and deuterochlorination in @NatureSynthesis! A tour de force led by Kangjie (Harry) Bian! www.nature.com/articles/s44...

Anti-Markovnikov hydro- and deuterochlorination of unsaturated hydrocarbons using iron photocatalysis - Nature Synthesis

Methods for the anti-Markovnikov-selective hydrochlorination of unsaturated C–C bonds are limited by the need for stoichiometric reagents, highly oxidizing photocatalysts and multiple synthetic steps....

nature.com

Coming up at the next @organicdivision.org Virtual symposium on Jan 15 @ 12 Noon ET our 2nd speaker will be Prof. Julian West @pushingarrows.bsky.social @ChemistryRice #ChemSky For more info: www.organicdivision.org/doc-virtual-...