Rachel Moran

@rachelmoran.bsky.social

Assistant Professor in Ecology & Evolution at UChicago. Evolutionary genomics and behavior in fishes. (she/her) https://rachelmoranlab.com

New paper out in PNAS! 🍇🧬 Vitis phylogenomics is a tangled vine. Highlights: • ~14% of the average grape genome comes from introgression • Two classic “hybrid species” are better described as hybrid swarms • Repeated adaptation is fueled by introgression and standing genetic variation

The dynamics of introgression and parallel adaptation across North American Vitis species | PNAS

Hybridization between species can contribute to parallel adaptive events. However, the prevalence of introgression is rarely measured across multip...

pnas.org

🧵 New paper! We’re excited to release OPTICS: software that immediately predicts color sensitivity from any opsin protein sequence. In other words: give OPTICS any opsin sequence, and it predicts the wavelength of light the pigment is most sensitive to 🌈👁️ academic.oup.com/mbe/advance-...

Accessible and Robust Machine Learning Approaches to Improve the Opsin Genotype-Phenotype Map

Abstract. Predicting phenotypes from genetic variation is a central challenge in biology. Here, machine learning (ML) offers great promise, but its use is

academic.oup.com

Paper alert!🧬🐦💻 Divergent selection is the textbook explanation for narrow inversion clines. Our blackcap inversion cline doesn't fit: it is wide, and the inversion is always the rarer arrangement. We show that negative frequency-dependent selection shifting between populations underlies this!

Shifting Balancing Selection Underlies an Inversion Cline in Eurasian Blackcap

We investigated what factor contributes to a cline of a chromosomal inversion of the Eurasian blackcap, which differs from typical inversion clines maintained by divergent selection. Using a simulati...

onlinelibrary.wiley.com

Researchers in the US might be having feelings about writing grants atm-I know I am! We still need to write them. In this Evolution Exchange, I again chat with Sam Scheiner, who summarizes how to write a competitive proposal. His advice is gold, and helpful regardless of funder. Pls RT!

Society for the Study of Evolution@sse-evolution.bsky.social · 5mo ago

💬 In the second installment of The Evolution Exchange, retired NSF Program Officer Dr. Sam Scheiner returns to discuss how to craft a successful research proposal. Watch or read the transcript here: www.evolutionsociety.org/the-evolutio...

Text: The Evolution Exchange, a monthly conversation series from the Society for the Study of Evolution. Outlines of cartoon heads with speech bubbles.

While our updated paper is fast approaching book-length, the results remain the same: our method (reconcILS) is still highly accurate. So if you want to reconcile gene trees and species trees--and you might have any ILS at all--this is the best method out there! www.biorxiv.org/content/10.1...

reconcILS: A gene tree-species tree reconciliation algorithm that allows for incomplete lineage sorting

Reconciliation algorithms infer the evolutionary history of individual gene trees given a species tree. Many reconciliation algorithms consider only duplication and loss events (and sometimes horizont...

biorxiv.org

New results on Littorina fabalis ecotypes! 🐌 Inversions aren't just enabling parallel adaptation to wave exposure in France & Sweden, they're also hotspots for site-specific differences, including a striking color QTL associated with one inversion but only in France. www.biorxiv.org/content/10.6...

Inversions support both parallel and location-specific adaptations in snail ecotypes

Replicated hybrid zones between ecotypes established over within shore environmental gradients provide an opportunity to study the genomic architecture of barriers to gene flow. The marine snail Litto...

biorxiv.org