Molly Schumer

@mollyschumer.bsky.social

Genetics & Evolution, Faculty at Stanford & Freeman Hrabowski Scholar at HHMI. My views do not reflect those of my employer. schumerlab.com

Pro-wrestling executive Linda McMahon issued a letter today (in her role as US Secretary of Education) demanding that universities justify their existence and explain policies to the Trump administration by the end of 2026. Not sure what the endgame is, but it sure feels like a trap.

U.S. Secretary of Education Linda McMahon Issues National Call to Action to University Presidents and Governing Boards

Today, U.S. Secretary of Education Linda McMahon issued a national call to action to university presidents and governing boards, urging them to reaffirm higher education’s foundational commitments to ...

ed.gov

The Chen Lab @ EMBL Rome (current population: 1) is hiring! Looking for an experimental Lab Manager w/ a PhD and experience in molecular bio and mouse-based neuro research. Apply if you like: mouse behaviors, high-throughput sequencing, good coffee & ancient history tinyurl.com/48h66vfh

Lab Manager

The European Molecular Biology Laboratory (EMBL) is one of the world’s leading life science research organizations. With sites across Europe, EMBL fosters an international, collaborative, and inclusiv...

tinyurl.com

Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...

Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS

In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...

pnas.org

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Beyond providing insight into the centromere paradox, this work demonstrates that complete chromosome reconstruction is now possible from wild-caught flies, opening new opportunities for population, functional, and quantitative genomics in Drosophila. Preprint here: www.biorxiv.org/content/10.6...

A conserved architectural domain shapes centromere evolution in Drosophila

Centromeres ensure faithful chromosome segregation despite being embedded within rapidly evolving repetitive DNA, a contradiction known as the centromere paradox. While centromere identity is defined ...

biorxiv.org

Delighted to share our paper on neo-chromosomes! We induced centromere fission using CRISPR in Arabidopsis and increased the chromosome count from n=5 to n=6. The broken chromosomes ends quickly “healed” by adding telomeres de novo and the new karyotype is stable through mitosis and meiosis! 1/3

Ian Henderson@hendersi.bsky.social · 2w ago

CRISPR-mediated centromere fission generates neochromosomes with distorted meiotic inheritance in Arabidopsis biorxiv.org/content/10.6... new preprint from us - includes changing the Arabidopsis karyotype from 5 -> 6 chromosomes using Cas9 & outcomes of 5/6 chromosome hybrid meiosis

Caroline Langley's primary thesis chapter from her time as a grad student in @memerman.bsky.social's and my lab is now published. She shows that HIV-1 Vif’s ability to maintain A3G antagonism depends on structural robustness, which permits adaptation, and epistasis, which imposes constraints.

@JohnGrossSF@johngrosssf.bsky.social · 2w ago

Strain-specific epistasis shapes fitness landscapes of APOBEC3G antagonism by HIV-1 Vif proteins | Science Advances www.science.org/doi/10.1126/... Congratulations on this beautiful work!

Very excited to share our new manuscript by Arif Maulana @arf-mln.bsky.social on 338 beetle genomes. It shows how beetle genomes have evolved and how this compares to fly and Lepidoptera genome evolution. It was a great pleasure to collaborate with @kamilsjaron.bsky.social and his team on this.

KamilSJaron.bsky.social@kamilsjaron.bsky.social · 2w ago

New preprint: 338 coleopteran genomes reveal exceptional rearrangement variation compared to other insect orders. Big congrats to @arf-mln.bsky.social, for getting this giant piece together. Big collaboration of @joanameier.bsky.social's and my groups. 🧵👇 doi.org/10.64898/202...

Phylogeny of 338 species with tips painted by the chromosomal ancestry of their contemporary genomes (well separated colours indicate only few changes, while blending indicates rearrangements). Colouring of the branches is by the number of rearrangements. The ring between paints and phylogeny indicates wether the chromosomal rearrangement was fusion dominated (brown) or fission dominated (teal) process.  
Photo credits: Udo Schmidt, Lech Borowiec, JL Tachet, David Navrátil, Fred Chevaillot, Siga, Cosmin Manci, John Hallmén, Igor Souza-Gonçalves, Alex Hyde, H. Coiffait, David Ignace, Yves Bousquet.

Trump science adviser['s] proposal to reduce the role of universities would up end [the] system in place since WWII. His call for the administration to de-prioritize life sciences...raised alarms among biomedical researchers" www.nytimes.com/2026/07/22/u...

Trump’s Plan for Science: More Money for A.I., Less for Universities

Michael Kratsios, President Trump’s science adviser, proposed overhauling how the government funds research. Democrats said Mr. Trump’s actions had weakened science.

nytimes.com

Super proud and excited about this work, led masterfully by Peiwei Chen! A fun and fruitful collaboration with department colleagues Andy Clark & Alexei Aravin. After 30 yrs of studying transposons, this is one of the very first times I see them jump in real time in their natural host! Hurrah! 🥳

Peiwei Chen@peiwei-chen.bsky.social · 3w ago

How do transposons jump when they’re released from host control? I babysat two chromosomes for 2 years, making sure they are ok without most piRNAs. Here’s what we found & excited to share my 1st postdoc paper: “piRNA loss unleashes episodic transposition bursts” www.biorxiv.org/content/10.6...

Just had a great zoom with a very talented undergraduate student from another country I would love to recruit. I really don't love telling students not to come here, but because our funding and visa situation is so volatile I can't in good conscience recommend a PhD in the US.

Delete and repost to clarify degree of uncertainty: Today there is substantial uncertainty racing through academic channels about how this atrocious rule will be interpreted and enforced. Apparently some current visa holders have received notice, so it may pertain to existing visas as well.

Trump Administration Issues Final Rule to End Foreign Student Visa Abuse | Homeland Security

DHS announced the publication of a final rule that officially eliminates the “duration of status” loophole that allowed foreign students, exchange visitors, and media representatives to remain in the ...

dhs.gov

On Wednesday, Munster will make his initial appearance before a judge over charges related to allegedly smuggling non-infectious MPXV without declaring it. The case has become a cause célèbre for Republican politicians and activists who have been targeted virologists for years. My reporting:

Smuggling charges against NIH virologists trigger political uproar

Other researchers say that non-infectious viral samples in luggage posed no risk, but might have violated import rules.

nature.com

Yesterday the US Administration supercharged its explicit effort to bar international students from staying in the US after graduation. All Americans should know: 1/3 of *all* STEM PhDs working in the US are immigrants who graduated from US universities, then stayed. www.piie.com/index%2Ephp/...

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How do transposons jump when they’re released from host control? I babysat two chromosomes for 2 years, making sure they are ok without most piRNAs. Here’s what we found & excited to share my 1st postdoc paper: “piRNA loss unleashes episodic transposition bursts” www.biorxiv.org/content/10.6...

piRNA loss unleashes episodic transposition bursts

In Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon ex...

biorxiv.org

Got this email from UConn Office of Vice President for Research, reminding us of the new NIH policy that any co-authorship with foreigners needs to have *prior approval* from NIH. It should be disclosed in advance in the grant proposal, or approval requested if collaboration arises later. What BS

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NEW: The Trump admin finalized a regulation which makes the largest changes to the student visa process in 50 years, along with changes to rules for exchange visitors and international journalists. 🧵on some of the most consequential changes set to go into effect in September.

AILA@aila.org · 3w ago

DHS has published its Final Rule to eliminate "duration of status" for F, J & I nonimmigrants. One of the most significant changes to international student, exchange visitor & foreign media programs in decades, it will be costly, cause chaos, and cut legal immigration.

CA leads the nation in scientific advancements & cutting-edge research. White House Office of Management and Budget new proposed rule puts all this in jeopardy & makes way for politically motivated decisions that serve the President over science.   They must rescind this rule immediately.

NEWS: As California Leads Nation in Scientific Advancements, Schiff, Lofgren, 42 Colleagues Urge OMB to Rescind Politicized Rule on Federal Grants

Washington, D.C. — U.S. Senators Adam Schiff (D-Calif.), U.S. Representative Zoe Lofgren (D-Calif.-18), and 42 members of the California congressional delegation are demanding the Office of Management...

schiff.senate.gov