What a time for sleep science!

Albert and Mary Lasker Foundation@laskerfdn.bsky.social · 7d ago

Congratulations to 2026 #LaskerAward winners Emmanuel Mignot and Masashi Yanagisawa! For identification of orexin, a brain peptide that maintains wakefulness, and the discovery that orexin deficiency causes uncontrolled sleep in #narcolepsy — revealing a key insight into the nature of sleep. 🧪

‼️OUT NOW‼️ Our new review updates the current understanding of how parental behaviour is generated across mammalian brains 🧠 from sensory processing and hypothalamic circuits to hormones, plasticity and behavioural flexibility 🧑‍🧑‍🧒 Check it out here: www.nature.com/articles/s41...

Neural circuits for mammalian parental behaviour - Nature Reviews Neuroscience

Parental care is a conserved and robust feature of mammalian reproductive behaviour, but is highly variable, even within individuals. Jamieson and Kohl describe the neural circuits that drive parental...

nature.com

Curious about understanding sleep homeostasis? Find out more at our next “Emerging Scientist Talk” with Raffaele Sarnataro @rafsarnataro.bsky.social, Postdoc at the Francis Crick Institute @crick.ac.uk. 📅 July 1 at 11:00 a.m. 📍 Room NQ105, Martinsried Art by @somedonkey.bsky.social

Applications are now open for the inaugural CAJAL Advanced Neuroscience Training Course on Neurobiology of Sleep 😴🧠!!! 📅 Dates: 19 November – 8 December 2026 ⏳ Application Deadline: 3 July 🔗 Information and application: cajal-training.org/on-site/neur...

In this sharp and insightful essay, Hannah Critchlow takes us through the many ways in which our brains generate and use energy, and offers some helpful recommendations for looking after your brain health

How understanding bioenergetics can help our brain health | Aeon Essays

A brain fit for the 21st century is one that understands – and respects – its own bioenergetic foundations

buff.ly

Studies using fruit flies by @ox.ac.uk researchers @rafsarnataro.bsky.social & Dr Peter Hasenhuetl, are providing new insights into how sleep is controlled 💤 As two winners of the Emerging Neuroscientist Seminar Series 2025, they recently spoke at SWC ⤵️ www.sainsburywellcome.org/blog/what-fr...

A neuronal population clock for interval timing in Drosophila #Drosophila

Why do we feel an irresistible drive to sleep after being awake for too long? A recent study led by Prof. Anissa Kempf has revealed that, in fruit flies, a small set of neurons can sense when the fly needs rest. Learn more 👉 www.biozentrum.unibas.ch/news/detail/... @erc.europa.eu @snsf.ch #sleep

The mystery of sleep: How does the brain know when it’s time to sleep?

Why do we feel an irresistible drive to sleep after being awake for too long? A recent study led by Prof. Anissa Kempf at the Biozentrum has revealed that in fruit flies, a small set of neurons can se...

biozentrum.unibas.ch

Raffaele Sarnataro of ox.ac.uk presents this #SymposiumReview examining the #neurobiology of mitochondrial dynamics in #sleep 🧠 💤 🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Did you know that we are offering 4 travel grants every year? That's right! 500£ for conferences and workshops. Registration is still open for the last grant of 2025! Need some inspiration? Read about the experiences of our Q3 winner, @rafsarnataro.bsky.social www.antibodies.com/promotions/t....

Antibodies.com | Antibodies, Proteins, and ELISA Kits

Antibodies.com supplies high-quality antibodies, proteins, and ELISA kits to life science researchers at cost-effective prices. Discover more, for less.

antibodies.com

The Erice Statement on the Importance of Molecular Life Sciences Education (shorturl.at/BNvfv) calls for a global effort to strengthen molecular literacy through inquiry-based and evidence-driven education, for responsible citizenship💡🧬 Endorse it here: shorturl.at/PTmsh @iapartnership.bsky.social

Congrats @rafsarnataro.bsky.social, the winner of our quarterly travel grant, who is currently at #SfN25. We are both excited and proud to support this cool research on the mitochondrial origins of the pressure to sleep! Shout out to @sfn.org!

Presynaptic Release Probability Determines the Need for Sleep https://www.biorxiv.org/content/10.1101/2025.10.16.682770v1

Excited to share our new #biorxivpreprint: “Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1... We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

Sleep might be an “inescapable consequence” of aerobic metabolism, new findings in fruit flies suggest. By @vcallier.bsky.social #neuroskyence www.thetransmitter.org/sleep/mitoch...

Mitochondria set ‘ancient’ metabolic thermostat for sleep in flies, separate from circadian rhythms

During waking hours, a specialized set of sleep neurons in the fly brain accumulates reactive oxygen species, which eventually trigger sleep to clean up and repair the damage they do.

thetransmitter.org

✨ Now out in Biomedical Optics Express: Cleared tissue dual-view oblique plane microscopy 🔬: doi.org/10.1364/BOE.... (🧵1/6)

Happy to have given a tiny contribution (as tiny as a fly brain!) to this new light-sheet microscopy technology. Congratulations to @ld-light.bsky.social and the whole team

Liuba Dvinskikh@ld-light.bsky.social · last yr.

We demonstrate our method on biological samples with a range of RIs, including a whole fly brain 🧠 (imaged in < 3 min⚡) and > 1 cm long mouse bone 🐭🦴 (🧵 5/6).

🚨 What's the interplay between sleep and mitochondrial dynamics in neurons? I am happy to share this invited review I wrote for The Journal of Physiology @jphysiol.bsky.social 👉 physoc.onlinelibrary.wiley.com/doi/full/10.... 🧵 Thread 👇 #Neuroscience #SleepResearch

Neurobiology of mitochondrial dynamics in sleep

Abstract figure legend In neurons, variations in sleep history are accompanied by alterations in mitochondrial dynamics, including changes in size, fission and fusion events, the emergence of extra-l...

physoc.onlinelibrary.wiley.com

Un nuovo studio condotto in D. melanogaster rivela che il bisogno di sonno potrebbe nascere direttamente dal metabolismo dei neuroni. Il sonno, insomma, sarebbe una conseguenza inevitabile della respirazione cellulare www.scienzainrete.it/articolo/cos...

A cosa serve il sonno? La risposta può essere nel metabolismo neuronale

Perché dormiamo? La risposta a questa domanda rimane uno dei grandi misteri della biologia. Come scrisse il neurofisiologo Alan Rechtschaffen: «Se il sonno non avesse una funzione assolutamente vitale...

scienzainrete.it

Tired? Well that sleepy feeling may be driven by 'leaky' mitochondria, according to a new study. I spoke to Gero Miesenboeck from @ox.ac.uk for @nature.com all about the new study. It's here on the Nature Podcast at 12:11:

‘Stealth flippers’ helped this extinct mega-predator stalk its prey

Hear the biggest stories from the world of science | 16 July 2025

nature.com

Congratulations to the SWC Emerging Neuroscientists Seminar Series winners! - Dimokratis Karamanlis, University of Geneva - @rafsarnataro.bsky.social‬ & Peter S. Hasenhuetl, @ox.ac.uk - Saurabh Vyas, @columbiauniversity.bsky.social - @sblumenstock.bsky.social‬, University of California San Diego

Mitochondria may have been labelled the "energy powerhouses" of cells, but they also seem to have an underappreciated role in sleep.

Our brain's mitochondria may play a crucial role in the onset of sleep

Textbooks say that mitochondria exist to supply cells with energy, but experiments in fruit flies suggest they are also involved in sleep

newscientist.com

Thanks @dereklowe.bsky.social for featuring our work in @science.org blog "The Pipeline"

Derek Lowe@dereklowe.bsky.social · last yr.

“Why do we sleep” has been a surprisingly hard question. But it looks like the answer may be “ Because we breathe”. Our mitochondria need a break!

1/ 🚨 Our new paper is online in @nature.com! As its first author, I’m enthusiastic to finally share it with you all! 🎉 🧠 We discovered a mechanistic link between cellular energy metabolism and the control of the need to sleep 💤 👉 rdcu.be/ewwrA @oxforddpag.bsky.social @ox.ac.uk @medsci.ox.ac.uk 🧵 👇

Nature@nature.com · last yr.

Nature research paper: Mitochondrial origins of the pressure to sleep go.nature.com/40oC7Y4

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness academic.oup.com/brain/articl...

Honoured to be the guest on the 100th episode of the @neuroversepod.bsky.social podcast!🎙️ With Clara Lenherr and @carolina-soares.bsky.social, I discussed the neurobiology of sleep—a topic that continues to fascinate and challenge us. Thank you to the Neuroverse team for inviting me. 🧵👇

Cleared tissue dual-view oblique plane microscopy https://www.biorxiv.org/content/10.1101/2025.05.12.653537v1

Cleared tissue dual-view oblique plane microscopy https://www.biorxiv.org/content/10.1101/2025.05.12.653537v1

Nature research paper: Sleep pressure accumulates in a voltage-gated lipid peroxidation memory https://go.nature.com/4bG20He

Sleep pressure accumulates in a voltage-gated lipid peroxidation memory - Nature

Sleep-inducing neurons in Drosophila rely on Hyperkinetic, the β-subunit of the KV1 channel Shaker, to monitor sleep need by translating lipid peroxidation events into changes in the oxidation state of a stably bound NADPH cofactor.

go.nature.com

Why do we need to sleep? In a preprint, researchers posit that it may be an "inescapable consequence" of how we power our cells. That and more of the best in Science and science in this edition of #ScienceAdviser: www.science.org/content/arti... 🧪