Raimon Sunyer
@raimonsunyer.bsky.social
Associate professor at @unibarcelona.bsky.social • Previous RyC • NIH & @ibecbarcelona.bsky.social alumni • Interested in #CellMigration & #mechanobiology
To put science in Spain into context, the median project is 50k per year. That's basically doing guerilla science 🧪
Jose A. Esteban@jaestebancbm.bsky.social · 3w agoMuchos ya habréis visto la resolución provisional de los proyectos #PID2025 de la @ageinves.bsky.social Aquí va la distribución. La financiación media por proyecto se ha quedado como el año pasado. Y seguimos con 2/3 de los proyectos con <50 k€ por año. ☹️ www.aei.gob.es/convocatoria...
1906 Nobel Prize winner Santiago Ramón y Cajal's 'Advice for a Young Investigator' makes important points: 1. The only thing in your power is your preparation 2. Be suspicious of “brilliance” 3. Be appropriately respectful of authority, but no more 4. Balance concentration and relaxation 🔽
#ExposicionsCRAIUB 👁️ 🧬 Nova exposició virtual dedicada al genoma humà del @craiubbiologia.bsky.social 🔬 📚🌐 Una col·lecció de llibres en format digital que explora els conceptes clau d’aquesta disciplina 🖱️Visita-la al web del #CRAIUB ℹ️ https://ja.cat/frklz
How do cells combine cell-intrinsic & tissue-level cues create stable patterns during intestinal regeneration? 🤔 Our paper w/ @cschwayer.bsky.social @silviabarbiero.bsky.social @ehannezo.bsky.social @priscaliberali.bsky.social is out! 🥳 A thread on the theory part 🧵⬇️ www.cell.com/cell/fulltex...
Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning
During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...
cell.com
🔬 Your tax dollars once paid a physicist whose own colleagues told him he was wasting the university's money. In 1951, Charles Townes sat on a D.C. park bench and worked out, on the back of an envelope, how to force molecules to release coherent radiation. 🧵 1/5
Amid chaos in US science and geopolitical turmoil, Europe wants to position itself as a research haven — but questions about funding and innovation remain go.nature.com/4eJVq4l
Europe as science superpower: what it will take to rival the US and China
Amid chaos in US science and geopolitical turmoil, Europe wants to position itself as a research haven — but questions about funding and innovation remain.
go.nature.com
Is there a size limit for cells ? How can cells replicate inside the architecture of their environment? Why do cells self-destroy ? This 15-minute movie vimeo.com/1173229237 shows our 2026 edition of the Living Architectures project at the @museeorsay.bsky.social
😎 to have this out! --> stay tuned, this is a series about 📊#dataviz for #science 🧪
Nature Methods@natmethods.nature.com · 2mo agoWe are very excited to bring back our popular Points of View column, written by @helenajambor.bsky.social! Check out her first column in our July issue about the usage of color scales in scientific figures. www.nature.com/articles/s41...
I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇
Very excited to be sharing our new paper, just out in Nature Cell Biology! The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?
🚀 New preprint on bioRxiv! How do physical boundaries shape collective cell migration? We show that geometric confinement progressively suppresses ERK signaling waves and slows collective epithelial migration by pushing tissues into a mechanically compressed state. 👉🏼 doi.org/10.64898/202...
Geometric confinement regulates ERK signaling dynamics and collective migration
Collective cell migration is a fundamental process in morphogenesis, tissue repair, cancer invasion, and frequently occurs under geometric confinement in vivo. However, how confinement interfaces with...
doi.org
![A screen for adherens junction proteins regulating collective cell migration and testis morphogenesis reveals important roles for the Rab GAP RN-tre and the kinase Par-1
Sarah Clark, Siobhan Morris, Joseph Dordor, Lawrencia Semireka Amo, Renick Wiltshire, Taino Encarnacion, Maik Bischoff, Mark Peifer
doi: https://doi.org/10.64898/2026.05.22.727264
This article is a preprint and has not been certified by peer review [what does this mean?].
Abstract
Animal tissues have diverse architectures and cell behaviors across the epithelial-mesenchymal spectrum. Cell adhesion mediated by classical cadherins is foundational. Cadherins nucleate complexes of dozens of proteins connecting junctions to the cytoskeleton and signaling downstream. Many junctional proteins are well-studied in epithelia, but less is known about roles during mesenchymal migration. The nascent myotubes of the pupal Drosophila testis provide an excellent model for N-cadherin mediated mesenchymal migration. We combined a proximity proteomics dataset of adherens junction proteins in mammalian epithelial cells with genome-wide shRNA libraries knocking down Drosophila genes to begin to define the subset of junctional proteins important in mesenchymal migration. While N-cadherin is predominant, E-cadherin plays a supporting role. Surprisingly, several proteins with key roles in epithelial morphogenesis, including Afadins homolog Canoe, ZO-1s homolog Polychaetoid, and Par3s homolog Bazooka play at most modest roles. Twenty-two genes with diverse cell biological roles had strong to moderate defects in testis morphogenesis. These will provide a community resource. We followed up two. The kinase Par-1 is important for migration and gap closure, with knockdown phenotypes paralleling those of myosin. The Rab GAP RN-tre does not have roles until after migration and works in parallel with N-cadherin during testis spiralization.
Competing Interest Statement
The authors have declared no competing interest.
Funder Inf…](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:r3avzdjyhu6jm7vxia265ncu/bafkreidugglr2vul5hlcrj542yutvkt7dfhxfvtvqvqksx7khjx2yyijeu)
@sholtodavid.bsky.social Have you seen this WB from ThermoFisher? Still anti-p53 antibody, but another clone (MA-12648 instead MA5-12557). It also looks like that the band in lane 3 was rotated and reused in lane 4. Moreover, it seems that same band was used for the 2 different clones.
Frankly, if the company doesn't address this soon they are undermining their entire antibody business--i wouldn't buy one from them. Try CST
Reese Richardson@reeserichardson.bsky.social · 3mo ago@johanduchene.bsky.social @sholtodavid.bsky.social Spent the last hour looking, found ten more apparently manipulated Western blots in Thermo Fisher's antibody verification data (across eight different catalogued products). Thread below. www.thermofisher.com/antibody/pro...
Interested in our latest advances in durotaxis? Tomorrow I’ll be speaking at the DGZ Focus Workshop on Cell Adhesion and Mechanobiology, together with Irène Nagle, Jacopo di Russo, and Meryem Baghdadi. 🗓 May 19, 2026 🕐 12:00–13:45 CEST #Mechanobiology #CellMigration #Fibroblasts #Biophysics
Interested in our latest advances in durotaxis? Tomorrow I’ll be speaking at the DGZ Focus Workshop on Cell Adhesion and Mechanobiology, together with Irène Nagle, Jacopo di Russo, and Meryem Baghdadi. 🗓 May 19, 2026 🕐 12:00–13:45 CEST #Mechanobiology #CellMigration #Fibroblasts #Biophysics
𝗔𝗿𝗲 𝘆𝗼𝘂 𝗰𝘂𝗿𝗶𝗼𝘂𝘀 𝗮𝗯𝗼𝘂𝘁 𝗵𝗼𝘄 𝗹𝗶𝗴𝗵𝘁 𝗺𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝗲𝘀 𝗮𝗰𝘁𝘂𝗮𝗹𝗹𝘆 𝘄𝗼𝗿𝗸 𝗮𝗻𝗱 𝘄𝗵𝘆 𝘁𝗵𝗲𝘆 𝗺𝗮𝘁𝘁𝗲𝗿 𝘀𝗼 𝗺𝘂𝗰𝗵 𝗶𝗻 𝗹𝗶𝗳𝗲 𝘀𝗰𝗶𝗲𝗻𝗰𝗲𝘀? If so, I recommend diving into this FREE microscopy course 👉 www.ibiology.org/online-biology-courses/microscopy-series/
Save the date, next DGZ lunch meeting DGZ Focus Workshop Workgroup Cell Adhesion and Mechanobiology May 19, 2026 12:00 – 13:45 CEST Zoom-ID: 961 7810 6979 Passcode: DGZ_FW
#DivulgacióUB | 🎉 Torna el #ClínicObert, amb més de 100 activitats divulgatives (tallers, visites i xerrades) sobre salut, recerca i docència per donar a conèixer la vida al Campus Clínic. 📅 Dissabte 9 de maig 🕛 9:30-16:00 📍 Campus Clínic @medicinacs-ub.bsky.social @hospitalclinic.bsky.social
El Campus Clínic obre portes a la ciutadania el proper 9 de maig
La segona edició del Clínic Obert inclourà més d’un centenar d’activitats per a tots els públics.
web.ub.edu
Interested in molecular motors? Don’t miss this wonderful symposium in Salamanca on "The Structure and Workings of Molecular Machines" with an outstanding lineup of speakers. 📍 Salamanca, Spain 📅 Monday, June 22, 2026 🎟️ Attendance is free, but registration is required 👇👇👇
Do we really need scientific journals? blogs.egu.eu/geolog/2026/...
Publish or perish? Or is publishing perishing? Reflections from a Great Debate at EGU26
There’s a particular kind of energy you get in a conference room when something is about to matter. You can feel it before anything starts: chairs filling quickly, people sitting closer than usual, no...
blogs.egu.eu
We are #Hiring! Our lab is looking for a LabTech/Lab Manager! Take a look to our research here! physics-of-life.tu-dresden.de/team/pol-gro... Drop a line if you are interested to know more details! #labtech #labtechnician #biology #labtechnicians #labmanager #labwork #Xenopus #zebrafish #devbiol
My postdoc work with @pcusachs.bsky.social is finally out! We find that fibrillar adhesions play an important role regulating the timescales of nuclear mechanotransduction. You can read all about it here : www.nature.com/articles/s41563-026-02590-x Huge thanks to everyone involved!!
Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton - Nature Materials
Nuclear deformation and mechano-signalling are regulated by the coupling of vimentin cytoskeleton to the extracellular matrix through fibrillar adhesions, modulating the timescale of mechanotransducti...
nature.com
If you’d like to learn more about our recent work, I’ll be giving a virtual talk on May 19th 👇👇👇
DGZ.bsky.social@dgz.bsky.social · 3mo agoOn May 19 at noon, the next DGZ Focus Workshop will take place, this time on #CellAdhesion and #Mechanobiology, organized by Andrew Clark and Ada Cavalcanti-Adam. Speakers: Irene Nagle, Meryem Baghdadi, @raimonsunyer.bsky.social, Jacopo di Russo - join us!
On May 19 at noon, the next DGZ Focus Workshop will take place, this time on #CellAdhesion and #Mechanobiology, organized by Andrew Clark and Ada Cavalcanti-Adam. Speakers: Irene Nagle, Meryem Baghdadi, @raimonsunyer.bsky.social, Jacopo di Russo - join us!
Per Sant Jordi, us deixem una rosa feta de ciència 🌹🔬 Controlant la posició dels defectes topològics en nemàtics cel·lulars, s'han programat camps de forces 2D frustrats que es relaxen en formes 3D predictibles.
#SantJordiUB | 🌹📖 Bon Sant Jordi a tothom! Hi ha tradicions que no es qüestionen. #SantJordi és cultura, llibres i llengua. 💙 ➡️ Consulta les activitats de Sant Jordi a la #UniBarcelona: ub.edu/sant-jordi