🚨 Excited to share a review by our #FOR5762 project leader @thevilchezlab.bsky.social. This highlights how multimodal approaches can better capture the complexity of human aging. Great work by @sedakoyuncu.bsky.social and Dunja Petrovic! #MultiOmics #AgingResearch www.cell.com/cell/fulltex...

Bridging omics and physiology to build multimodal clocks of human aging

Human aging is a heterogeneous, multi-system process that spans molecular, tissue, and physiological decline. In this issue of Cell, Li et al. integrate clinical data, multi-omics, and organ-associate...

cell.com

Last week, we had the pleasure to welcome Oscar Fernandez-Capetillo and Tim Bartels in Cologne as part of our #FOR5762 seminar series. Thank you both for sharing your latest research with us and for the engaging discussions that followed. @cecad.bsky.social #proteostasis #neurodegeneration

🎉 #FOR5762 has awarded two Advanced Postdoc Grants. Congrats to Marta Zaninello and @sedakoyuncu.bsky.social on this well-deserved achievement. 👏 We look forward to following their independent research and their contributions within #FOR5762. @cecad.bsky.social | @uniklinikkoeln.bsky.social

We had the pleasure of hosting @mariaermolaeva.bsky.social from the leibnizfli.bsky.social. Maria presented her research as part of our #FOR5762 seminar series. Her talk led to an engaging exchange of ideas and a lively discussion with the group. #CircadianClock #Proteostasis #AgingResearch

📢 We’re excited to welcome @mariaermolaeva.bsky.social for our next #FOR5762 seminar! 🗓 March 10, 2026 🕑 14:00 📍 #CECAD Cologne – Lecture Hall Sleep deprivation and circadian disruption are known to negatively impact health - but how exactly do they affect proteostasis and aging?

📢 It's our pleasure to welcome Prof. Rick Morimoto for our next #FOR5762 seminar series! Talk: 'Cell Non-Autonomous Regulation of Organismal Proteostasis' 📅 Feb 26, 2026 🕑 2:00 PM 📍 MPI for Biology of Aging - Auditorium Looking forward to seeing you there!

🚨Excited to share this new review in @febsj.bsky.social by our #FOR5762 project leader @thevilchezlab.bsky.social! The article explores how organelle #proteostasis preserves cellular function, and how its decline contributes to #aging and disease. febs.onlinelibrary.wiley.com/doi/10.1111/...

FEBS Press

Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the n...

febs.onlinelibrary.wiley.com

🚨Thrilled to share this exciting new paper by our #FOR5762 project leader @bjornschumacher.bsky.social, published in #NatureAging! The study uncovers neuron-specific aging patterns and points to potential neuroprotective interventions. Congratulations! 🎉 www.nature.com/articles/s43...

Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions - Nature Aging

Gallrein et al. pair functional assays with clocks to compare chronological versus biological age of single neuron types in C. elegans, to probe their vulnerability or resilience to neurodegeneration,...

nature.com

🧠 Nerve cells age differently Researchers led by @bjornschumacher.bsky.social‬ @cecad.bsky.social have used C. elegans to prove for the first time that nerve cells age differently. Using an “aging clock” they were able to precisely determine the biological age of individual neurons👇 uni.koeln/FKJ35

Eine Alternsuhr der Nervenzellen findet Moleküle, die vor altersbedingter Neurodegeneration schützen www.idw-online.de/-DTSBAA

⏰🧠 Nervenzellen altern unterschiedlich Forschende um @bjornschumacher.bsky.social @cecad.bsky.social haben in C. elegans erstmals nachgewiesen, dass Nervenzellen unterschiedlich altern. Mit einer „Alternsuhr“ konnten sie das biologische Alter einzelner Neuronen präzise bestimmen👇 uni.koeln/BWMMP

Curious about the role our genetic traits 🧬 and our lifestyle 🏄‍♀️ play in healthy ageing? In the latest episode of the Bild der Wissenschaft podcast, our #CRC1678 project leader @bjornschumacher.bsky.social explains the science behind longevity! 🎙️Listen here: www.wissenschaft.de/gesundheit-m...

Bild der Wissenschaft PODCAST – Folge 13: Ein Autopilot für Schiffe

Cyril Alias erklärt, wie ein Autopilot Binnenschiffe durch Flussbiegungen und Stromschnellen navigieren könnte.

wissenschaft.de

Die großen Fragen der Wissenschaft | Können wir ewig leben? Im Gespräch geht es um die tiefgreifenden biologischen Mechanismen hinter dem Altern, ethische Grenzen bei der Lebensverlängerung und um sinnvolle Strategien, länger gesund zu leben detektor.fm/wissen/die-g...

Können wir ewig leben, Björn Schumacher?

Alternsforscher Björn Schumacher über ewiges Leben, unseriöse Versprechen und Faktoren, die das Leben wirklich verlängern können.

detektor.fm

Heute im @spektrum.de der Wissenschaft: mein Gespräch über »Altersuhren«, Fadenwürmer, den Traum von der ewigen Jugend und die richtige Medizin www.spektrum.de/news/longevi...

Die großen Fragen der Wissenschaft: Können wir ewig leben, Björn Schumacher?

Ein Gespräch mit dem Biologen Björn Schumacher über die Geheimnisse von Longevity – einem möglichst langen, gesunden Leben.

spektrum.de

Hier der Podcast: mein Gespräch über »Altersuhren«, Fadenwürmer, den Traum von der ewigen Jugend und die richtige Medizin youtube.com/watch?v=Q6ey...

Können wir ewig leben, Björn Schumacher?

YouTube video by detektor.fm

youtube.com

🚀 Now out in print: AGE DECELERATION AND REVERSAL GENE PATTERNS IN DAUER DIAPAUSE. How we can learn from nature of to slow aging and rejuvenate. Big congrats to Khrystyna Totska, João Barata, Walter Sandt, and @meyerdavid.bsky.social! @cecad.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

Age Deceleration and Reversal Gene Patterns in Dauer Diapause

The dauer diapause is a naturally occurring extraordinarily long-lived alternative C. elegans larval stage that, upon dauer exit, lives a normal adult life with full reproductive capacity. Here, we d...

onlinelibrary.wiley.com

🚨Check out this new preprint from our Research Unit member @irinadudanova.bsky.social uncovering vulnerability profiles of cortical cell types in #HuntingtonsDisease. @biorxivpreprint.bsky.social

Irina Dudanova@irinadudanova.bsky.social · 8mo ago

New preprint from the lab by Dennis Feigenbutz et al.: Using #snRNA-seq, we explore vulnerability profiles of cortical cell types in #HuntingtonsDisease mice and identify ER-phagy as a new pathway in HD pathogenesis. www.biorxiv.org/content/10.1...

🚨TOMORROW🚨 📢 We are excited to welcome Prof. Malene Hansen (Buck Institute for Research on Aging) for a seminar hosted by #FOR5762 and #RTG2550. “Cellular recycling in aging and disease - the importance of taking out the trash” 📅 Dec 3, 2025 🕓 3:00 PM 📍 MPI for Biology of Aging – Auditorium

🔥🔥🔥Now out in print: how do germ cells instruct the soma and how does the soma impact inheritance? Together with Shoma Ishikawa we provide a comprehensive overview of The Somatic Impact on Inheritance and the Germline Control of the Soma - www.annualreviews.org/content/jour...

The Somatic Impact on Inheritance and the Germline Control of the Soma

The faithful transmission of genomic DNA over succeeding generations is an essential prerequisite for species maintenance. The germplasm theory by August Weismann has been foundational for the current...

annualreviews.org

🚨Exciting news: A recent study from our #FOR5762 member @thevilchezlab.bsky.social has been selected for the cover of @febsletters.bsky.social! Huge congrats to @thevilchezlab.bsky.social, Saygın Bilican and all co-authors for this fantastic highlight on #ALS-linked #Nup107 mislocalization! 🎉

David Vilchez@thevilchezlab.bsky.social · 9mo ago

Saygin’s new ALS paper — showing nucleoporin alterations — just made the journal front cover @febsletters.bsky.social febs.onlinelibrary.wiley.com/doi/10.1002/... febs.onlinelibrary.wiley.com/doi/10.1002/...

🚨 Thrilled to share this exciting new paper by our #FOR5762 member Prof. Thorsten Hoppe. This study reveals how leucine boosts mitochondrial function by protecting key proteins. Congratulations! 🎉 @cecad.bsky.social @unicologne.bsky.social @natcellbio.nature.com

From food to fuel: How leucine enhances mitochondrial energy production

Researchers from the University of Cologne discovered how a specific dietary amino acid increases cellular energy, opening new possibilities for treating metabolic diseases / publication in “Nature Ce...

cecad.uni-koeln.de

🚨 Speaker Alert! 🚨 We’re thrilled to host @uweohler.bsky.social for the next #CRC1678 Seminar! 🧬 He’ll present: "Dissecting Regulatory Networks from Single-Cell Multi-Omics Data" 📅 November 6 📍 CECAD Lecture Hall ⏰ 3:00 PM Explore the frontier of computational biology and cellular complexity!

🧬🧬🧬Targeting Genome Stability to Mitigate Human Aging and Disease - read now our comprehensive review article written with Debbie Toiber how we can target the most fundamental mechanisms of aging and cancer. @annualreviews.bsky.social 🔗 go.shr.lc/3JohYMp

a computer generated image of a dna molecule with a dark background

ALT: a computer generated image of a dna molecule with a dark background

media.tenor.com

📢 We are thrilled that our Research Unit #FOR5762 is hosting this joint seminar with #CRC1678! Don't miss Prof. Bernd Bukau's talk about 'Mechanisms of Co-Translational Folding and Assembly of Proteins' !

CRC1678@crc1678.bsky.social · 10mo ago

🚨 Speaker Alert! 🚨 We’re excited to welcome Prof. Bernd Bukau (ZMBH Heidelberg) for the next #CRC1678 Seminar! 🧬 Talking About Mechanisms of Co-Translational Folding and Assembly of Proteins 📅 October 23 📍 Auditorium, MPI for Biology of Ageing ⏰ 2:00 PM Join us!

🚨Check out this new study from our Research Unit member @bjornschumacher.bsky.social on gene expression patterns linked to age deceleration and rejuvenation during Dauer Diapause. Congratulations! 🎉

Björn Schumacher@bjornschumacher.bsky.social · 10mo ago

🚀 🚀 🚀 Our latest paper is out now: Age Deceleration and Reversal Gene Patterns in Dauer Diapause. We can learn from nature how aging of a whole organism with completely differentiated tissues can be slowed and how that organism can be completely rejuvenated. onlinelibrary.wiley.com/doi/10.1111/...

🎉What a wonderful way to wrap up the CGA Welcome Days! Today's party was a lot of fun! There was delicious "homemade" food, an exciting pub quiz, and just the nicest group of people. A big thank you to our PhD reps, Moritz and Anna, for putting everything together! We all really enjoyed ourselves.

🚨 Just 3 weeks left to apply for our 12 PhD positions in ageing research! 🚨 🏃‍♀️ Don't wait- hurry up and submit your application now! ✉️

Cologne Graduate School of Ageing Research@cga-age.bsky.social · 12mo ago

Apply now for a fully funded #PhD position at the Cologne Graduate School of Ageing Research and become part of our vibrant #AgingResearch commmuny. 🗓️ Deadline: November 3, 2025. ℹ️ More info: www.ageing-grad-school.de 📣 Spread the news!

It was great fun speaking with Debbie Toiber and @barakrotblat.bsky.social on my path to science and why studying aging is so important to me. open.spotify.com/episode/2brg...

Prof. Dr. Björn Schumacher

open.spotify.com

Barak Rotblat@barakrotblat.bsky.social · 10mo ago

A fantastic podcast with @bjornschumacher.bsky.social 🙏and Debbie Toiber about Bjorn's scientific path through the science of aging open.spotify.com/episode/2brg... Part of our undergrad course 'biology for non biologists'

🧓How aging drives neurodegenerative diseases🧠 @thevilchezlab.bsky.social @cecad.bsky.social has identified a direct molecular link between aging and neurodegeneration by investigating how age-related changes in cell signalling contribute to toxic protein aggregation.

⏰🔬⏳What if we could prevent age-related diseases before they even start? At #CECAD Cologne, that’s exactly our #mission! In this new video, Prof. Dr. Carien Niessen shares our vision uncovering the biology of #aging to improve #health. #HealthyAging @unicologne.bsky.social youtu.be/9ALNLpG3oYc

CECAD: Our Scientific Mission

YouTube video by CECAD Cologne

youtu.be