Ryosuke Fujii (Ryo)

@ryo-epi.bsky.social

Genetic Epidemiology | Previously Senior Researcher, Eurac Research 🇮🇹 --> Now Senior Assistant Professor, Fujita Health Univ. 🇯🇵 https://sites.google.com/view/ryosukefujii/home

NIH All of Us has just released a massive multi-omics dataset, including: • 535K WGS (120K+ added; now larger than UKB) • ~10K proteomics + RNAseq + long-read • ML-curated clinical notes • 68K with Fitbit data Kudos to this great initiative and to the participants for advancing science

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We consider 12,871 parent–offspring trios, which is quite unique data. Strikingly, paternal education-PGI predicts offspring income more strongly than the offspring’s own education-PGI. This pattern applies only to paternal PGI, not maternal PGI!

📣 𝐖𝐞’𝐫𝐞 𝐡𝐢𝐫𝐢𝐧𝐠 𝐚 𝐩𝐨𝐬𝐭𝐝𝐨𝐜 𝐢𝐧 𝐩𝐨𝐩𝐮𝐥𝐚𝐭𝐢𝐨𝐧 & 𝐬𝐭𝐚𝐭𝐢𝐬𝐭𝐢𝐜𝐚𝐥 𝐠𝐞𝐧𝐞𝐭𝐢𝐜𝐬! 🌍📈🧬 If you’re finishing a PhD (or know someone who is) and want to work on complex trait biology + 𝑟𝑒𝑎𝑙-𝑤𝑜𝑟𝑙𝑑 𝑖𝑚𝑝𝑎𝑐𝑡, read on 👇

🗓️ Join @prsmethods.bsky.social investigators on May 13 to discuss integrating Social Determinants of Health (SDoH) and polygenic risk scores 👀 Event information: bit.ly/4chGKtr 🔖 Publication: pubmed.ncbi.nlm.nih.gov/41785862/

American Society of Human Genetics: Incorporating Polygenic Risk Scores and Social Determinants of Health Across Populations

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American Society of Human Genetics (ASHG)@geneticssociety.bsky.social · 4mo ago

The authors take the mic. In this upcoming May 13 Journal Club Webinar, @ajhgnews.bsky.social’s paper authors Sara J Cromer, MD, MS, and David Conti, PhD, unpack what it takes to integrate PRS and SDoH across genetically and socially varied populations—LIVE: https://bit.ly/4chGKtr #ASHG

Sara J Cromer, MD, MS

Our review "Integrating genetic data with biological insight: A practical guide to cis-Mendelian randomization" is now published at @ajhgnews.bsky.social - led by @vkarhune.bsky.social and Benji Woolf with critical insight from Dipender Gill and Pallav Bhatnagar. Thread follows:

The American Journal of Human Genetics@ajhgnews.bsky.social · 4mo ago

📣New Review! 📄Integrating genetic data with biological insight: A practical guide to cis-Mendelian randomization 🧑‍🤝‍🧑 @vkarhune.bsky.social @stevesphd.bsky.social & co 👉 bit.ly/4tKkY7r

@fctropf.bsky.social and I are running a 2-day short course in London on 20/21 April that will provide an introduction to polygenic scores. The course will cover creation of polygenic scores, their strengths and limitations, and ethical issues around their use. Further info at shorturl.at/8gUcu.

Introduction to polygenic score analyses in the social, behavioural, and health sciences

This 2-day course will provide social scientists with the knowledge and skills needed to understand the creation of polygenic scores, critically interpret their use in studies, and integrate them into...

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