This seems a good prompt for your annual reminder to avoid azide reactions in DCM #ChemSky #ChemChat

Diazidomethane Explosion

An explosion that caused extensive damage to a 20-L rotary evaporator and nearby equipment in a kilo laboratory was determined to have been caused by diazidomethane accumulated in the condenser. Facto...

pubs.acs.org

Nessa Carson@supersciencegrl.co.uk · 4w ago

First time I've seen substitution into DCM actually wanted! Only 3 equiv CH2Cl2 will mitigate problems, as amines + CH2Cl2 make thermally unstable products: a pain & explosion risk. CH2O byproduct not great for further low-level imps. But very innovative! #chemsky pubs.acs.org/doi/10.1021/...

A loooong journey to this: Energetics, Shock Sensitivity, and Thermal Hazards of Cubane and Bicyclo[1.1.1]pentane Derivatives | Organic Process Research & Development pubs.acs.org/doi/10.1021/...

Energetics, Shock Sensitivity, and Thermal Hazards of Cubane and Bicyclo[1.1.1]pentane Derivatives

Strained polycyclic ring structures such as cubanes and bicyclo[1.1.1]pentanes (BCPs) are gaining popularity as isosteres in the pharmaceutical and agrochemical industries. It has been previously repo...

pubs.acs.org

Any experienced peptide chemists out there looking for a new challenge? I have an opening on my team vrtx.wd5.myworkdayjobs.com/en-US/vertex...

Process Chemistry Senior Principal Scientist, Synthetic Peptide Chemist

Job Description General Summary: Vertex is seeking an experienced peptide chemist to join the Process Chemistry group. In this lab-based position you will be responsible for the synthesis, purificatio...

vrtx.wd5.myworkdayjobs.com

Huge loss for the chemistry community. Absolutely loved my time at UPenn. I wouldn’t be where I am today if it wasn’t for Amos’ mentorship and the friends I made in the group

Penn Chemistry@pennchemistry.bsky.social · 2y ago

We are deeply saddened to share that our friend and colleague Professor Amos B. Smith III has passed away. Amos joined Penn in 1973 and was a mainstay in our organic chemistry division. He recently celebrated 50 years of service to @upenn.edu @pennsas.bsky.social.

If you care about visualization of scientific data and creating clear, impactful scientific publications, I highly recommend this podcast featuring my esteemed colleague Bang Wong. He also has a fantastic set of papers on this topic #DataVisualization www.buzzsprout.com/558574/episo...

S5E6: Writing Impactful Publications - NINDS's Building Up the Nerve

In the fifth Season of the National Institute of Neurological Disorders and Stroke’s Building Up the Nerve podcast, we help you strengthen your science communication skills with tools and advice to us...

buzzsprout.com

Probably my most controversial fb post (back when I actually used fb)

Me trying In and Out for the first time

a man in a blue shirt is talking to a woman in a brooklyn nine-nine episode .

ALT: a man in a blue shirt is talking to a woman in a brooklyn nine-nine episode .

media.tenor.com

My favorite line when recruiting for process chem:

The long and ugly story of Cassava Sciences’ supposed Alzheimer’s drug simufilam is finally over. It should have ended well before this.

The Cassava Saga Finally Ends

science.org

Skeetorial time! Let’s talk early human dose prediction. Not the fancy, need-tons-of-software and a DMPK pro kind. Just the kind that uses some basic algebra. HDP is a unifying concept for med chemists. It’s the master optimization parameter, and it can’t be easily cheated. 1/

a pink background with pills and capsules on it

ALT: a pink background with pills and capsules on it

media.tenor.com

Thank you @kcortiz.bsky.social

Created a Starter Pack for Industry Chemists- let me know if you want in! #ChemSky

Hard agree with all of this. Basic setting up of profile with pic and bio increases confidence in identity. Not that accounts can’t be spoofed, but it’s a start. My follows are flooded these last few days and I know I’m doing a lousy job of follow-backs. Help me know you’re you!

Dr. Stephanie@punkrockscience.bsky.social · 2y ago

Hey, new users! Remember how suspicious Twitter egg profiles were? No one trusts a blank profile. Set an avatar, set a background, write your bio, and maybe post a couple of times before you start mass-following people, okay?

PSA for #ChemSky

Love seeing my followers drop on X

Anybody going to CO for fall ACS?

Getting into festive spirit with some chem Christmas carols. #chemsky #nmr #chemistry #science #christmas

THE REACTION IS SAFE IF RUN IN A SEALED VIAL!

Scott Bagley@bagphos.bsky.social · 3y ago

ALL OF MY SUZUKI-MIYAURA REACTIONS ARE ORGANOCATALYZED!

I started two manuscripts this week and I feel very academic

Reskeet with how people would know if you suddenly became rich

Deb@debramayberry.bsky.social · 3y ago

Reskeet with how people would know if you suddenly became rich.

Next for #NationalChemistryWeek ⚛️ (theme “The Healing Power of Chemistry”), here are some things I think are true that I’ve distilled about drug discovery over time. This series was originally posted on the other app and was livelier with GIFs, but I’ll record them here anyway.

5+ hr flight and no one sitting beside me

This is the first time I’ve been asked to review a paper where the chemistry actually blows my mind. Very cool stuff

Using an image, show a movie you are sure you have watched more than 10 times

Chemjobber@chemjobber.bsky.social · 3y ago

Using an image, show a movie you are sure you have watched more than 10 times.

Chemists working with stannanes in the 1960s

Maybe a little late to this party but thanks for the invite @chemjobber.bsky.social 👊🏻