Sam Scarpino

@scarpino.bsky.social

Scientist. Director of AI + Life Sciences and Professor of Public Health, Health Sciences, & Computer Sciences at Northeastern University. External Professor at the Santa Fe Institute and Vermont Complex Systems Institute. scarpino.github.io

One of the biggest misconceptions about Ebola is that it is primarily a hemorrhagic disease. It isn't. In the current Bundibugyo Ebola outbreak in the DRC, fever, vomiting, and diarrhea dominate at presentation, while bleeding occurs in only ~10% of patients. www.nejm.org/doi/full/10....

Clinical Characteristics of Patients Infected with Bundibugyo Virus, DRC 2026 | NEJM

Bundibugyo virus, a filovirus, is currently spreading in the Democratic Republic of Congo. This report presents early data on symptoms and illness severity as well as diagnostic challenges.

nejm.org

1/ The past 36 hours have been significant for the ongoing #hantavirus outbreak. I still think the risk is low, but we're almost certainly going to see more cases. Here's what I'm watching: 1. Three new positive individuals (French, US, Spanish). 2. Four viral genomes. 3. Ship fully evacuated.

Sam Scarpino@scarpino.bsky.social · 3mo ago

1/ Yesterday I was more worried about #hantavirus than I am today. Why? Flight attendant who was exposed - Tested negative Viral genome - No concerning mutations Two Singaporean's exposed - Tested negative Data situation - We're tracking at Global.health (h/t @mugkraemer.bsky.social)

Another fantastic Student Research Symposium organized by NetSI PhD students! With faculty across Boston, Portland, and London, 35+ attendees per session, and inspiring early PhD presentations, it was a great success. The future of network science is in great hands!

Now that we’re back, I want to promote this awesome work from our group led by former UG Researcher, Gillian Patton (now a Ph.D student at Wash U) published in Evol. Letters! We blocked a first step mutation that typically promotes biofilm formation to see how this roadblock influences evolution.

Evolution Letters@evolletters.bsky.social · 7mo ago

Evolution isn’t always forward-looking. Experiments show that an early, beneficial mutation can trap E. coli on a local fitness peak, preventing ecotype diversification in structured environments and highlighting the role of G×E interactions. academic.oup.com/evlett/advan...