***Publication alert*** "Pathological tau alters head direction signaling and induces spatial orientation" www.cell.com/cell-reports...
Shan Jiang
@shanjiang.bsky.social
DPhil Neuroscience, University of Oxford, spatial navigation, sleep; postdoc McGill
www.pharm.ox.ac.uk/news/new-stu...
New study reveals specialised subpopulations of head direction cells in the mouse thalamus
Researchers from the Viney Group in the Department of Pharmacology, along with collaborators from The Center for Systems Neuroscience, Boston University, US, have identified distinct subpopulations of...
pharm.ox.ac.uk
Second paper from my PhD out ✌️
Tim Viney@vineytj.bsky.social · 4mo agoNew paper out in Current Biology. We define thalamic head direction (HD) cells based on the combination of neurochemical identity, physiology, sensorimotor responses, and connectivity, suggesting cell types. Great work led by Sara Hijazi and Shan Jiang from the lab. www.cell.com/current-biol...
A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...
Place cells in CA1 lack topographical organization of firing locations | PNAS
Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...
pnas.org
I don't think I'll ever get bored of looking at raster plots of head-direction cells 🤩
Applications are now open for the summer school: 𝐌𝐚𝐭𝐡𝐞𝐦𝐚𝐭𝐢𝐜𝐚𝐥 𝐌𝐞𝐭𝐡𝐨𝐝𝐬 𝐢𝐧 𝐂𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐜𝐞 🧠 Apply before March 15: www.compneuronrsn.org 📍 Located in beautiful Eresfjord 🇳🇴 🗓️ Between July 6-24 Supported by the @kavlifoundation.org In collaboration with @kavlintnu.bsky.social
Mathematical Methods in Computational Neuroscience
Summer school in Eresfjord, Norway (July 8th - 26th, 2024)
compneuronrsn.org
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
The postsubiculum as a head-direction cortex
The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…
sciencedirect.com
*New preprint from the lab* – “Granularity of thalamic head direction cells” doi.org/10.1101/2025... 🧠📈 🧪 1/11
Granularity of thalamic head direction cells
Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...
doi.org
First spring hippocampus conference in Verona! Great experience with interesting talks and meeting amazing people there;)
Pleased to say our study led by James Street showing a requirement for the LGN pathway for visual landmark control of head direction cells is now published! physoc.onlinelibrary.wiley.com/doi/10.1113/...
The dorsal thalamic lateral geniculate nucleus is required for visual control of head direction cell firing direction in rats
Abstract figure legend Head direction cells in the rodent postsubiculum (PoS) are oriented by environmental visual cues, assessed in the laboratory using a cue-controlled environment. We investigated....
physoc.onlinelibrary.wiley.com
Pleased to share our #neuroscience preprint on how tau pathology affects head direction cells of the anterodorsal thalamus and induces disorientation, an early sign of #dementia
bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2y agoPathological tau alters head direction signaling and induces spatial disorientation https://www.biorxiv.org/content/10.1101/2024.11.07.622548v1