Immensely grateful to the @beckman-foundation.bsky.social for supporting our lab’s work on viral immune evasion, and honored to join the Beckman Young Investigator Program!! I look forward to being part of this incredible community 🤩

Beckman Foundation@beckman-foundation.bsky.social · 2mo ago

Congratulations to our 2026 Beckman Young Investigator Awardees! Twelve Researchers Selected to Receive $7.2M in Total Science Funding for Cutting-edge Research www.beckman-foundation.org/latest-news/... #BYI #beckmanresearch #newlyawarded

Tomorrow at the #SystemsVirologyJournalClub, William Bakhache (@williambakhache.bsky.social) will present his work with Patrick Dolan (@ptdolan.bsky.social) on the constraints that shape Enterovirus A71 evolution using deep mutational scanning. pubmed.ncbi.nlm.nih.gov/39609576/

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/

Tomorrow at the #SystemsVirologyJournalClub @mayavoichek.bsky.social will present her work with @juliusbrennecke.bsky.social on the discovery of direct cell-to-cell transmission of retrotransposons. Paper: biorxiv.org/content/10.1...

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Tomorrow at the #SystemsVirologyJournalClub, Ivan Zheludev will present his work with Andrew Fire on the discovery of viroid-like RNAs that are associated with the human microbiome. Join us! Paper: pubmed.ncbi.nlm.nih.gov/39481381/

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Tomorrow at the #SystemsVirologyJournalClub, @finkelyaara.bsky.social will present her work with @sginossarlab.bsky.social on engineering HCMV to express sgRNA libraries directly from the viral genome to profile virus-host interactions across the infection cycle. Join us!

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Beautiful work from the Nemudryi lab discovering tRNA-targeting antiviral immunity in bacteria.

Artem Nemudryi@artemnemudryi.bsky.social · 5mo ago

Our work on bacterial Schlafens in phage defense is out today @natmicrobiol.nature.com! Check out the final version here: rdcu.be/e7Bmz We are looking for postdocs and students to expand our team! Official postings are coming soon. Please reach out if you're interested! #phage #phagesky #microsky

Abstract submission is now OPEN for the 2026 Symposium on the Immune System of Bacteria! sisb2026.rockefeller.edu 🗓 May 5–7, 2026 📍 Rockefeller University, New York City ⏰ Abstract deadline: March 16, 2026 Attendance will be capped, be sure to register early and secure your spot. See you in NYC!

As we are sending back the revised version of our pooled prime editing gene tagging paper, I am happy to share a website for design of prime tagging libraries, including some images, all generated from a single pooled transduction and in situ sequencing. primetagging.org

Tomorrow at the #SystemsVirologyJournalClub, Joel Tan (@joelmjtan.bsky.social) will present his work with Philip Kranzusch (@kranzuschlab.bsky.social) on a DNA-gated molecular guard that control bacterial anti-phage defence. Paper: pubmed.ncbi.nlm.nih.gov/40306316/

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Now out in Nature! We visualize infection of the RNA virus RSV in real-time with single-vRNP resolution to understand how RSV establishes viral factories, biomolecular condensates that act as sites of viral replication. A huge collaborative effort led by Dhanushika Ratnayake! rdcu.be/e1bBW

Pre-assembly of biomolecular condensate seeds drives RSV replication

Nature - Viral ribonucleoprotein–viral protein networks form pre-replication centres that nucleate viral factories and drive respiratory syncytial virus replication.

rdcu.be

Join us tomorrow at the #SystemsVirologyJournalClub. @lauraluebbert.com will present her work with @lpachter.bsky.social on detecting viruses at single-cell resolution and uncovering associated changes in host gene expression. Paper: pubmed.ncbi.nlm.nih.gov/40263451/

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Tomorrow, at the #SystemsVirologyJournalClub, @samuelhking.bsky.social will present his work with @brianhie.bsky.social using AI genome language models to generate novel, high-fitness bacteriophages.

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Coming in at #4 in our Top 5 Countdown: virus hunters assemble! Dr. @shiraweingarten.bsky.social at @harvardmed.bsky.social launched the Laboratory of Systems Virology. We cannot wait to see what the lab accomplishes in 2026! https://bsky.app/profile/scienceinboston.com/post/3lsuek25o5c2f

Science in Boston@scienceinboston.com · last yr.

Dr. Shira Weingarten-Gabbay (@shiraweingarten.bsky.social) from @harvardmed.bsky.social is leading the new Laboratory of Systems #Virology. Her lab uncovers the inner workings of viruses and their interaction with the immune system to prevent current and future viral diseases: bit.ly/44peaBa

A remarkable recognition in Nature’s 10 for @merbllab.bsky.social and her team at #WeizmannInstitute the mindblowing discovery of a defense mechanism in human cells mediated by proteasome-derived antimicrobial peptides 🤩 www.nature.com/articles/d41...

This scientist found a new trick of the immune system by digging through cellular rubbish

Yifat Merbl is part of Nature’s 10, a list of people who shaped science in 2025.

nature.com

🚨ATTENTION EARLY CAREER VIROLOGISTS🚨 We have a webinar on how to get a faculty position! Hear from Jean Lim, @drsprggs.bsky.social and @tylernstarr.bsky.social. Check your email for registration link and form to submit questions in advance.

Tomorrow (Thursday) at the Systems Virology Journal Club, Noor Youssef will present her work with Debbie Marks on developing an AI model that predicts how viruses evolve to evade the immune response. Paper: pubmed.ncbi.nlm.nih.gov/40345199/

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Tomorrow at the #SystemsVirologyJournalClub Yingpu Yu will present his work with Charles Rice on the cis preference of HBV polymerase to its transcript. Spoiler alert: it involves #ribosome stalling! 😍 Paper: pubmed.ncbi.nlm.nih.gov/38723628/

Shira Weingarten-Gabbay@shiraweingarten.bsky.social · 10mo ago

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

🚨 Systems Virology Journal Club – 8th Series! 🚨 #BillSchneider and I are delighted to announce another round of cutting-edge talks in #SystemsVirology! 🦠💡 Join us and an outstanding lineup of speakers, starting Oct 30. Free registration: shiraweingartengabbay.com/systems-viro... 🔬✨

Congratulation to all the laureate and finalists and to the brilliant Maria Cecilia Canesso 🤩

The Rockefeller University @rockefeller.edu · 11mo ago

Congratulations to all, especially Rockefeller's @veenapadmanaban.bsky.social, a research associate in @sohailtavazoie.bsky.social's lab, and Maria Cecilia Campos Canesso, formerly a postdoc in @danmucida.bsky.social and @victora.bsky.social’s labs. A very well-deserved recognition!

Looking forward to a terrific symposium on Synthetic Biology and it's implication in therapeutic development ✨

Akos Nyerges@akosnyerges.bsky.social · 11mo ago

Excited to chair #BostonDOT 's SynBio symposium with talks from 🔸Farren Isaacs 🔸Jessica Stark @jcstark.bsky.social 🔸Shira Weingarten-Gabbay @shiraweingarten.bsky.social 🔸Abhishek Chatterjee @achemsynbio.bsky.social 🔸Wen Tseng 🔸Michael Krogh Jensen 🔸Ryan Clarke 🔸Alex Reis @alexcampreis.com

Preprint: De-novo design of proteins that inhibit bacterial defenses Our approach allows silencing defense systems of choice. We show how this approach enables programming of “untransformable” bacteria, and how it can enhance phage therapy applications Congrats Jeremy Garb! tinyurl.com/Syttt 🧵

Synthetically designed anti-defense proteins overcome barriers to bacterial transformation and phage infection

Bacterial defense systems present considerable barriers to both phage infection and plasmid transformation. These systems target mobile genetic elements, limiting the efficacy of bacteriophage-based t...

biorxiv.org

SPEAR (bacterial nanosynringe) enables loading of different types of cargo (including folded ribonucleoproteins and single-stranded DNA) and targeting of defined cell types both in vitro and in vivo www.nature.com/articles/s41... @natbiotech.nature.com @zhangf.bsky.social

Excited to share our new @natmicrobiol.nature.com paper revealing the most complete arenavirus glycoprotein complex (GPC) structures to date 🤩 www.nature.com/articles/s41...

Molecular organization of the New World arenavirus spike glycoprotein complex - Nature Microbiology

Cryo-EM structures of the full-length Junin virus and Machupo virus spike glycoprotein complexes stabilized in the prefusion conformation. Analyses reveal features that regulate glycoprotein pH-depend...

nature.com

Super interesting insights on the evolutionary constrains on synonymous codons 🤩 "Our results suggest that cotranslational localization and translational accuracy, more than cotranslational protein folding, are major drivers of selective pressure on codon choice in eukaryotes."

Liana Lareau@lianafaye.bsky.social · 12mo ago

This preprint from Helen Sakharova is one of the coolest things to come out of my lab: “Protein language models reveal evolutionary constraints on synonymous codon choice.” Codon choice is a big puzzle in how information is encoded in genomes, and we have a new angle. www.biorxiv.org/content/10.1...

The most humble scientist I know and a true legend

Matt Frieman@mattfrieman.bsky.social · last yr.

Charlie Rice is the only scientist who could get a Nobel Prize for his findings and give a keynote address at #ASV2025 and never mention he won a Nobel Prize! #LoveVirology

On my way to #ASV2025. Two flights canceled due to weather ⛈️ but should make it on time! Join us for a terrific symposium tomorrow morning on #NextGenerationVirology with #BenhurLee #JesseBloom #LisaWagner @wchnicholas.bsky.social and #IleanaCristea. Safe travel everyone! #LoveVirology

Get ready for ASV 2025! The 2025 American Society for Virology meeting will be hosted by McGill University and held at the Palais des Congrès de Montréal, Montréal, Québec, Canada from July 14 - 17, 2025. Abstract submission, travel award apps, and registration are now open! asv.org/asv2025/regi...

Register 2025 | American Society for Virology

The 44th Annual Meeting of the American Society for Virology! Dates: July 14 – 17, 2025 (Monday – Thursday) Palais des congrès de Montréal Host: McGill University *TEACHER TRAVEL GRANTS: Applications…

asv.org

Dr. Shira Weingarten-Gabbay (@shiraweingarten.bsky.social) from @harvardmed.bsky.social is leading the new Laboratory of Systems #Virology. Her lab uncovers the inner workings of viruses and their interaction with the immune system to prevent current and future viral diseases: bit.ly/44peaBa

"This work by Shira highlights new dark matter in viral genomes that can influence disease and how we design vaccines," says Charles Rice. "It’s yet another layer of biology that was not appreciated but opens up exciting new opportunities for exploration."