Dr. Sarah Signor
@signor-molevol.bsky.social
Assistant professor at NDSU. I love all things Drosophila & TEs & Gene regulation. Mostly bioinformatics but you'll find me with a pipette.
Congratulations to @rpianezza.bsky.social @rokofler.bsky.social, Matt Beaumont and Sarah Saadain! We found an endogenous retro virus currently invading D. melanogaster!
The ongoing invasion of the endogenous retrovirus Kuruka in natural Drosophila melanogaster populations - Nature Communications
Transposable elements are mobile DNA sequences that can copy themselves and spread between species. This study finds that Kuruka, a retrovirus-like transposon, invaded Drosophila melanogaster within t...
nature.com
super proud - my very first review is online www.annualreviews.org/content/jour... many thanks to @signor-molevol.bsky.social @rpianezza.bsky.social @almoroscarpa.bsky.social for the fun collaboration
The History of Transposable Element Invasions in Drosophila melanogaster
As a fundamental biological principle, genomic information is typically transmitted vertically from parent to offspring. Occasionally, however, genetic material is transferred horizontally between spe...
annualreviews.org
How do you teach a research based intro to genomics course without it just being an intro to Linux course
New paper with Nick Davies and Kevin Foster in @natcomms.nature.com. We show that often neither selection against transposons’ deleterious effects nor exploitation by parasitic elements is sufficient to keep them in control. Only active host suppression does. www.nature.com/articles/s41...
Checking out the latest trends in Hawaiian shirts #Evol2026
Anywhere that let's you input a list of genus names and outputs the taxonomy, not the taxonomy code?
I'm really excited to tell my kids about this. Krakens are real! 🤣 www.science.org/doi/10.1126/...
Earliest octopuses were giant top predators in Cretaceous oceans
Top predators drive changes in ecosystem structure. For the last ~370 million years, large-sized vertebrates have dominated the apex of the marine food chain, while invertebrates have served as smalle...
science.org
I need a rec for a black and white lab printer we can ruin everything but we can't make a decent printer
Happy to begin the year with the publication of a Journal Club article - Programmed ‘DNA splicing’ removes transposons from genes. rdcu.be/eXBym
Programmed ‘DNA splicing’ removes transposons from genes
Nature Reviews Molecular Cell Biology - A study that showed that programmed DNA elimination in somatic genomes of ciliates involves excision of intrusive, transposon-derived sequences from genes.
rdcu.be
In a new study, Sarah Marion &co use genetic mapping and whole genome sequencing in wild #Drosophila to reveal the genetic basis of naturally occurring lethal mutations and introduce a new model that could explain their frequencies in natural populations. 🧪 #genetics
Transposable elements contribute substantially to naturally occurring genetic lethality in Drosophila melanogaster
Recessive lethal mutations are common and often persist at unexpectedly high frequencies due to diverse mutational causes. This study shows that many lethal alleles in Drosophila melanogaster arise…
plos.io
The TE workshop at #dros26 last night was fantastic! Great networking and talks. Thanks @levine-lab.bsky.social @mobilepurin.bsky.social and Chris Ellison
Looking forward to Carolus Chan speaking this morning on transposon silencing in the nasuta group ##dros26
Slamming coffee and gummy worms to stay awake for this incredible TE workshop #dros26
What happens if the germline goes on without (most of the) piRNAs for 45 generations? Come find out at my talk at the evolution session on Saturday at #dros26 @genetics-gsa.bsky.social 🪰🔬🔎⁉️🤔
Raymond Huey is giving an incredible rundown on the effect of elevation on human physiology for Darwin day @ndsu-biosci.bsky.social
Birthdays, tenure, manuscripts, graduations. It's a good time in the Signor lab!
You can call me Dr. Associate Professor (tenure)
It was my daughter's 7th birthday yesterday and LOOK AT THIS CAKE
@5calls.org just do anything do something just call
