Tobias Fellinger
@stats-tobby.bsky.social
Interested in biostats, R, regulatory science, clinical trials, time to event analysis, causal inference, ... he/him
Bill’s early work had an incredible influence on my career, especially his studies on perception and coplots. It’s so sad to hear that he passed away. May his memory be a blessing.
Attila Bátorfy@attilabatorfy.bsky.social · 4mo agoOhh, no! :( www.dignitymemorial.com/obituaries/c...
one of my favourite experiences in writing art code is when the code base is just complex enough that you can almost predict what it will produce, but not quite, leading to pieces that aren't exactly what you were expecting #rstats
Did you know the FDA has gone full Bayesian? Better take in this blogpost, including intro to the context of guidance documents The guidance is quite good, but as stated in the blogpost, it leaves out where the FDA finds Bayesian methods acceptable. statmodeling.stat.columbia.edu/2026/01/15/f...
FDA guidance on Bayesian clinical trials | Statistical Modeling, Causal Inference, and Social Science
statmodeling.stat.columbia.edu
In other #regulatory news: FDA has released their draft guidance on #Bayesian Methods for public consultation. This guidance has been under development for quite some time and is a good overview about the regulatory thinking / interpretation of Bayesian methods. www.fda.gov/media/190505...
fda.gov
In joint work with #EMA and #FDA colleagues we wrote down 10 guiding principles of good #AI practices in #drugdevelopment that are now finally published 🎉 They are quite general and hopefully universally agreed upon, detailed guidance will follow. www.fda.gov/media/189581... #pharma #regulatory
fda.gov
Should statistical software that estimates causal effects also tell you the causal assumptions under which that estimate can be interpreted as causal? I don't know but my PhD student Maurice Korf has some thoughts (and software) to get the conversation going: academic.oup.com/ije/article/...
Causal clarity in statistical software
Imagine running a simple regression in any statistical software of choice—but this time, you only get a point estimate of the regression coefficient. There
academic.oup.com
The distinction between causal, predictive, and descriptive research—there is still room for improvement - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...
The distinction between causal, predictive, and descriptive research—there is still room for improvement
It has been proposed that medical research questions can be categorised into three classes: causal, predictive, and descriptive. This distinction was proposed to encourage researchers to think clearly...
jclinepi.com
Great experience with a novel format of an invited session of #stratos TG2 @biometricsociety.bsky.social Austro-Swiss region meeting (ROeS 2025 Graz) (1/n)
doi.org/10.1002/sim.... Our paper "A Comparison of Statistical Methods for Time-To-Event Analyses in Randomized Controlled Trials Under Non-Proportional Hazards" got published today 🎉 We describe commonly used methods, and compare their performance in a simulation study across different scenarios.
A Comparison of Statistical Methods for Time‐To‐Event Analyses in Randomized Controlled Trials Under Non‐Proportional Hazards
While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best inferential approach under non-proportional hazar...
doi.org
An LLM "creates textual claims, and then predicts the citations that might be associated with similar text. Obviously, this practice violates all norms of scholarly citation. At best, LLMs gesticulate toward the shoulders of giants." Bender, West, and I contributed to this pro/con piece in PNAS.
How should the advancement of large language models affect the practice of science? | PNAS
Large language models (LLMs) are being increasingly incorporated into scientific workflows. However, we have yet to fully grasp the implications of...
pnas.org
Paper finally acxepted after 3 years of work on the project with a large consortium 🎉 I'll post a link, when it's published
Hallo, Bluesky! Wir sind neu hier und freuen uns, Teil dieser Community zu werden! Freut euch auf spannende Inhalte rund um die Gesundheit von Mensch, Tier, Pflanze und Umwelt. Sagt "Hi" in den Kommentaren und folgt uns für mehr! 💛 www.ages.at
I have the greatest respect for graphics in scientific papers before computer graphics and even pen plotters were a common thing. Just beautiful 😍
Hi bluesky 👋 Hope there's some biostats people here, all the R people are also on mastodon but biostats wise it's been a bit lonely since leaving twitter
Key question to consider before submitting your paper on the development and validation of your new clinical prediction model is: WHERE IS THE MODEL????