Structural Phylogenetics (StrPhy)
@strphy.bsky.social
Structural Phylogenetics • methods, datasets, tools, events • concise updates for researchers and practitioners. Managed by @proteinmechanic.bsky.social and @cpuentelelievre.bsky.social
The 2026 SMBE Australasian Protein Structural Phylogenetics Meeting took place last week in Brisbane (Australia) to discuss this rapidly growing field. Thank you to all participants and congratulations to the organizing team, who brought to life a fantastic event!👏 @strphy.bsky.social #StrPhy26
APSPM brought together researchers from around the world to explore protein evolution from different angles. Structural approaches are reshaping evolutionary inference and the community is growing. Huge thanks to participants and @official-smbe.bsky.social for making this meeting a success. #StryPhy
APSPM2026 - What can we learn from ancient protein history? @joannamasel.bsky.social will open with her research tracing how the genetic code first evolved and the surprising origin of tryptophan. @official-smbe.bsky.social #StrPhy26 #StrPhy
Thank you @fabianruperti.bsky.social for sharing your research with us today. It sparked timely and interesting conversations. #StrPhy26
Fabian Ruperti@fabianruperti.bsky.social · 6mo agoTalking about structure-based protein annotations in weid critters (or „Why we shouldn’t say ‘structural homolog’!”). Thanks for having me @strphy.bsky.social #StrPhy #StrPhy26 #StructuralPhylogenetics
APSPM2026 - Today's session starts with @claudiaalcar.bsky.social Charting the protein universe: Deep evolutionary signals in sequence structure space (remote). She'll present her work on exploring how protein folds emerged and diversified over billions of years. #StrPhy26 #StrPhy
Biochemistry Alumni Lecture –APSPM 2026 Mon 16 Feb 14:30–15:30 Exploring the Protein Universe with Multimers, Motifs & Interfaces @martinsteinegger.bsky.social will present their fast computational methods to search and cluster across these structural layers. From structure to function to evolution.
Opening plenary APSPM 2026: Protein structure characters in the light of phylogenetic systematics by @nicholasmatzke.bsky.social A thought-provoking talk that revisits classic systematics concepts to address the question: are structural differences evolutionary signals or methodological artefacts?
Meet the APSPM 2026 organisers: Caroline, Jordan and Ashar. We're 3 ECRs based in Australia/NZ passionate about protein evolution and developing new approaches and applications to advance this exciting field. biosig.lab.uq.edu.au/strphy26/org... @official-smbe.bsky.social
Only 3 days to go before APSPM 2026 starts! In-person attendees, we'd love for you to join us for drinks and nibbles by the riverside on Sunday, Feb 15 at 5.30pm at Southbank Beer Garden. See you there! www.southbankbeergarden.com.au
The program is now live. An excellent global lineup of speakers - AUS, NZ, Korea, India, Laos, UK, Switzerland, France, Finland, Germany, Hungary, Japan, Uruguay, Mexico and USA. Browse abstracts. Just 3 weeks left. Super excited. #StrPhy26 #Science #Evolution #StrPhy #StructuralPhylogenetics
Structural Phylogenetics (StrPhy)@strphy.bsky.social · 6mo agoThe program for the SMBE Australasian Protein Structural Phylogenetics Meeting 2026 is now out! Abstract book coming soon. @official-smbe.bsky.social @proteinmechanic.bsky.social biosig.lab.uq.edu.au/strphy26/pro...
The program for the SMBE Australasian Protein Structural Phylogenetics Meeting 2026 is now out! Abstract book coming soon. @official-smbe.bsky.social @proteinmechanic.bsky.social biosig.lab.uq.edu.au/strphy26/pro...
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
One month to go until APSPM 2026! Scientific program coming soon.
An interesting way to look at encoded structural characters to build alignments and trees downstream. This takes structural phylogenetics one step further in the post-AlphaFold era. #Evolution #Science #StrPhy On Confidence Assessment in Structure-Aware Alignments doi.org/10.1093/gbe/...
Structome-AlignViewer: On Confidence Assessment in Structure-Aware Alignments
Abstract. Protein structure-based comparison provides a framework for uncovering deep evolutionary relationships that can escape conventional sequence-base
doi.org
We have reached full capacity for in-person attendance at #APSPM2026 and registration is now closed. Thanks to everyone who registered. Accepted talks and travel grants will be announced in the upcoming weeks.
We have had an amazing response to #APSPM2026 and only a few in person spots are still available. Abstract submissions and travel grant applications close tomorrow November 28. 👉 biosig.lab.uq.edu.au/strphy26/reg... Join the community that is transforming protein evolution research.
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
SMBE Australasian Protein Structural Phylogenetics Meeting 📄 Abstract submission deadline: Nov 28 Please submit your abstracts by Friday! Registration is free, but limited to 50 in-person attendees. ✈️ Travel grant applications deadline: Nov 28 🔗 biosig.lab.uq.edu.au/strphy26/str...
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
Registration for #APSPM2026 closes soon. Everyone’s welcome! whether you study evolution, structure, or computational methods, join us in Brisbane (and online) Feb 16–18, 2026 to learn how protein structure meets phylogenetics. biosig.lab.uq.edu.au/strphy26 @official-smbe.bsky.social
From AI to ancestral proteins, the #APSPM2026 speaker lineup brings protein evolution research together in one place. Check out the list of confirmed speakers here: biosig.lab.uq.edu.au/strphy26/spe... Brisbane + online Feb 2026 Free registration @official-smbe.bsky.social
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
Meet the plenary speakers for #APSPM2026. Joanna Masel @joannamasel.bsky.social Nicholas Matzke @nicholasmatzke.bsky.social Join us to discuss how protein structure is changing evolutionary theory, phylogenetics and molecular evolution. biosig.lab.uq.edu.au/strphy26/spe...
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
Structure-informed phylogenetic inference with FoldTree outperforms sequence-only trees on divergent proteins, and untangles RRNPPA quorum-sensing receptors across Gram-positive bacteria & phages. Work led by David Moi (www.linkedin.com/in/david-moi) Paper: doi.org/10.1038/s415...
Viral protein sequences are highly variable, but structures are much more conserved. In this paper, David Moi et al. present a highly accurate method to infer phylogenetic trees from 3D protein structures — opening new ways to explore viral evolution and protein function.
Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses - Nature Structural & Molecular Biology
Using a new method called FoldTree, the authors compare proteins on the basis of their shape to construct more accurate family trees over long evolutionary timescales and capture distant relationships...
nature.com
We have had some amazing abstracts submitted to the free @official-smbe.bsky.social APSPM meeting. To help you make up your mind, here is a sneak peek. Join for what will be an amazing meeting. biosig.lab.uq.edu.au/strphy26/sneakpeek/ . #StrPhy26 @strphy.bsky.social #Evolution #Science
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
February 2026 is shaping up to be the month for protein science down under! Lorne (Feb 8–12) @lorneproteins.bsky.social APSPM 2026, Brisbane (Feb 15–18) biosig.lab.uq.edu.au/strphy26/str... Two meetings and a summer of great science! @strphy.bsky.social @official-smbe.bsky.social
#APSPM2026 is open to anyone curious about combining protein structure and evolution. Learn where to start in our workshops and discover how structure meets phylogenetics. Feb 15 - 18, 2026 Brisbane, Australia Register here: biosig.lab.uq.edu.au/strphy26/reg... (in-person only)
We can’t wait to welcome you to sunny Brisbane. Home to world-class research and a vibrant scientific community. Join us at the University of Queensland for #APSPM2026 to discuss how protein structure and evolution come together #StrPhy26
Abstract submissions are open for #APSPM2026! 🗓️ Deadline: Nov 28, 2026 📍 Brisbane + online 🎓 Travel grants for students & ECRs Join us to explore how protein structures and AI are reshaping evolutionary biology. @official-smbe.bsky.social #StrPhy26 #StrPhy
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
The conference will be held on the beautiful St Lucia campus of The University of Queensland. Plenary speakers are @joannamasel.bsky.social (University of Arizona, USA) and Nicholas Matzke (University of Auckland, NZ). Registration is free, but spaces are limited to 50 in-person attendees.
Structural phylogenetics is poised to reshape our understanding of molecular evolution. While the availability of structural data has exploded, its integration into evolutionary analysis has yet to reach its full potential. This meeting provides a timely forum to explore this frontier.
We are excited to announce APSPM 2026 - the SMBE Australasian Protein Structural Phylogenetics Meeting! 🗓️ 15-18 Feb. 2026 🌏 Brisbane, Australia 🔗 biosig.lab.uq.edu.au/strphy26/ 📄 Abstract submission: 28.11.2025 ✈️ Travel grant application: 28.11.2025 ✏️ Registration: 15.01.2026 #StrPhy26
APSPM 2026: Structural Phylogenetics Meeting
A pivotal SMBE regional meeting in Brisbane on the interface of protein structure, function, and evolution.
biosig.lab.uq.edu.au
