Great visuals from the Global Disease Burden showing that both communicable and infectious diseases in decreasing quality of live in the world. Novo Nordisk Foundation Global Science Sunmit

🧵1/3 Virus size matters! Ebolavirus particles are among the largest viruses known to infect humans. Individual particles often package multiple genome copies. Virus size: viralzone.expasy.org/5216 ViralZone ebolavirus: viralzone.expasy.org/11865

‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.

‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools

Nature - Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.

nature.com

Scavenger receptor class F member 2 is an intracellular receptor for hepatitis B virus

Scavenger receptor class F member 2 is an intracellular receptor for hepatitis B virus

Li et al. identified SCARF2 as an intracellular receptor for HBV entry that directs internalized HBV to nuclear pore complexes and facilitates nucleocapsid release from endosomes.

cell.com

virological.org/t/initial-ge...

Initial genomes from May 2026 Bundibugyo Virus Disease Outbreak in the Democratic Republic of the Congo and Uganda

Initial genomes from May 2026 Bundibugyo Virus Disease Outbreak in the Democratic Republic of the Congo and Uganda, reveal a new spillover event Context On 15 May 2026, the Ministry of Public Health, ...

virological.org

A rough guide to the location of the latest outbreak of infection and disease caused by a virus from the species of orthoebolaviruses called 𝘖𝘳𝘵𝘩𝘰𝘦𝘣𝘰𝘭𝘢𝘷𝘪𝘳𝘶𝘴 𝘣𝘶𝘯𝘥𝘪𝘣𝘶𝘨𝘺𝘰𝘦𝘯𝘴𝘦 affecting eastern Democratic Republic of the Congo and Kampala, in Uganda.

Ebola outbreak kills 65 people in eastern Democratic Republic of the Congo

Ebola outbreak kills 65 people in eastern Democratic Republic of the Congo

Concerns raised that cases were caused by a new strain of the virus as African health officials race to coordinate and contain the infection An outbreak of Ebola has killed 65 people in the Democratic Republic of the Congo, according to African health officials. There have been 246 suspected cases of the deadly haemorrhagic fever reported so far in Ituri province, which shares borders with Uganda and South Sudan. Continue reading...

theguardian.com

Need accurate graphics of Hantavirus virions? ViralZone has you covered. Free to use in any media, modify as needed—just cite the source (CC BY license). viralzone.expasy.org/resources/An...

ViralZone Andes virus resource now includes comprehensive outbreak data from the 2026 cruise ship incident. New additions: expanded fact sheets, dedicated glycoprotein pages, complete variant information, and an updated virion illustration. viralzone.expasy.org/11845

With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...

My ANDV #Hantavirus @nextstrain.org phylogenies now pull directly from @pathoplexus.org to incorporate all seqs I'll continue to improve them, & will keep them updated Change the Tip Labels in the left-hand menu. You can see links to all builds, plus tanglegrams at: nextstrain.org/groups/hodcr...

1/ 🚀 Pathoplexus now supports the Andes variant of Hantavirus (ANDV). ANDV is the variant identified in the recent MV Hondius cases, & the Hantavirus variant previously identified as having occasional human-to-human transmission. pathoplexus.org/andv #hantavirus #hondius

virological.org/t/complete-s...

Complete sequence of Orthohantavirus andesense virus: Swiss resident 2026

Posted on behalf of the Swiss National Reference Center for Emerging Viral Infections, Geneva University Hospitals and the Institute of Medical Virology, University of Zurich (Partner Laboratory Natio...

virological.org

Geneva University Hospital has identified the hantavirus responsible for the outbreak on a cruise ship as Andes virus. This is one of the rare hantaviruses known to be capable of human-to-human transmission. www.hug.ch/en/actualite...

Hantavirus outbreak on a cruise ship : The HUG have identified the strain of the virus

hug.ch

A NEW PHASE OF SARS-COV-2 EVOLUTION? The evolution of SARS-CoV-2 has followed a familiar pattern: new variants emerged, spread rapidly across the globe, and replaced their predecessors - triggering successive waves of infection.

Identification of hot spring Obelisk-like RNA replicons and expanded diversity of the Obelisk superfamily | Nature Communications https://www.nature.com/articles/s41467-026-71096-6

Identification of hot spring Obelisk-like RNA replicons and expanded diversity of the Obelisk superfamily - Nature Communications

In this study, the authors identify circular RNAs replicating in high-temperature hot spring environments and demonstrate that ccc RNA replicons belonging to the Obelisk superfamily are more diverse and widespread than previously recognized, revealing hidden RNA systems in natural environments.

nature.com

New transcription signals in SARS-CoV-2 reshape virus–host interactions journals.plos.org/plosbiology/...

New transcription signals in SARS-CoV-2 reshape virus–host interactions

Non-spike changes driving SARS-CoV-2 fitness remain undiscovered. This Primer comments on two PLOS Biology papers that show that evolutionary N gene mutations create a transcription-regulating sequenc...

journals.plos.org

Argentina reports hundreds of new chikungunya cases open.substack.com/pub/outbreak...

Argentina reports hundreds of new chikungunya cases

In a follow-up on the chikungunya outbreak in Argentina, the Argentina National Epidemiological Surveillance System (BEN) reports 268 new cases of chikungunya fever during the week ending April 11.

open.substack.com

I have the pleasure of giving a talk at this year's SFV meeting.

Société Française de Virologie (SFV)@sfvirologie.bsky.social · 4mo ago

Dorian McILROY, maître de conférences à @univ-nantes.fr, est invité aux #JFV2026. Sa présentation portera sur "SV40, BKPyV et JCPyV dans le cancer: faux positif, fausse identité, ou vrai coupable?"  @dmcilroy.bsky.social  Plus d’infos 👉 https://jfv-2026.sciencesconf.org/

What shapes the human DNA virome? Analysis of blood & saliva shows persistent viruses (EBV, HHV-6B, HHV-7, anelloviruses), with viral load varying by age, higher in men, and influenced by host genetics (MHC, ERAP1, ERAP2).

Nature@nature.com · 4mo ago

Nature research paper: The DNA virome varies with human genes and environments go.nature.com/3Pyb5uC

The official taxonomy of viruses have just been updated ictv.global/news/MSL41 Updated data in: ICTV 2025 master species list (MSL41) ictv.global/msl Virus Metadata Resource 2025 (MSL41) ictv.global/vmr

🎉 Registration for ECCB 2026 is now open! Join the computational biology community in Geneva for 5 days of science & collaboration. Organized by the @sib.swiss Institute of Bioinformatics. ⏰ Early bird until 31 March 📆 31 Aug - 4 Sep 2026 👉 eccb2026.org/registration... #eccb2026 #GenevaLovesData

Preprint: Identification and structural characterisation of a picornavirus integrin receptor with an essential role of two distinct glycans for virus infection www.researchsquare.com/article/rs-9...

AlphaFold database has entered the era of complexes. Together with NVIDIA, DeepMind and EBI, we use ColabFold, OpenFold and MMseqs2-GPU to predict ~31 million complexes (homo & hetro-dimers) resulting in 1.8 million high-quality predictions 📄 research.nvidia.com/labs/dbr/ass... 🌐 alphafold.ebi.ac.uk

@ecallaway.bsky.social wrote a news article on our AlphaFold complex work. Thank you for covering it. 📄 www.nature.com/articles/d41...

AlphaFold hits ‘next level’: the AI database now includes protein pairing

The database of 200 million protein-structure predictions now includes homodimers, adding new biological relevance.

nature.com

Nature research paper: Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor go.nature.com/4urU3yb

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor - Nature

Marburgvirus glycoprotein binds to the endosomal receptor NPC1 in a distinct orientation with higher affinity compared with Ebola virus glycoprotein, accompanied by fusion-relevant rearrangements, enabling more efficient viral entry.

go.nature.com

Scientists say they have made some of the first direct measurements of how long it takes an individual, ordinary protein to fold – and the results were surprising. go.nature.com/3N4UrSD

How fast does a protein fold? Real-time technique captures the moment

Proteins assume complex 3D shapes even faster than does DNA, which is a simpler molecule.

go.nature.com

Influenza A(H3N2) subclade K (J.2.4.1) dominated this winter (>80% of infections in the Northern Hemisphere). Baseline antibody titers to subclade K variants were lower than to other H1N1/H3N2 strains—and vaccine-induced responses were also significantly weaker. jamanetwork.com/journals/jam...

Out today: We discovered new viral proteins that target immune signaling molecules, solely based on their AlphaFold-predicted shapes www.science.org/doi/10.1126/... Congrats Nitzan Tal and coauthors! Thank you Kranzusch lab for the fun collaboration! Linking below previous thread on our findings

Structural modeling reveals phage proteins that manipulate bacterial immune signaling

Immune systems in animals, plants, and bacteria often rely on intracellular nucleotide signaling, which viruses can block by sequestering or degrading these signals. We identified structural and bioph...

science.org

Nitzan Tal@nitzantal.bsky.social · last yr.

📢Preprint out! Excited to share my final work from the @soreklab.bsky.social! We mined phage dark matter using structural features shared by anti-defense proteins (viral tools that help phages bypass bacterial immunity) to guide discovery. Found 3 new families targeting immune signaling!

⏰Abstract submission for #ViBioM2026 is open until midnight tonight (00:00 CET) - Don't miss your chance to present a talk at the International Virus Bioinformatics Meeting! 🎤🦠🧬💻 👉 evbc.uni-jena.de/events/vibio... #virology #bioinformatics

European Virus Bioinformatics Center@evbc.bsky.social · 5mo ago

📢 Submit your abstract for ViBioM 2026 in Vilnius!! Share your work and be part of the International Virus Bioinformatics Meeting on 18-20 May! #virology #bioinformatics #ViBioM2026 🎤 Talk Abstract Deadline: 6 March 2026 📜 Poster Title Deadline: 17 April 2026 🔗 evbc.uni-jena.de/events/vibio...