***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social

Generative replay across hippocampal-neocortical circuits

To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...

biorxiv.org

Feeling really proud of this one: a review of Bayesian efficient coding with Máté Lengyel and Paul Bays (@bayslab.org) is now available online in TICS! authors.elsevier.com/a/1nF3i4sIRv...

plane read🤓! shoutout @sumedhanalluru.bsky.social & all for this very cool piece🧠

Brain Network Dynamics Unit@bndu.ox.ac.uk · 4w ago

New unit paper on "The hippocampus as a generative model", published in Philos Trans R Soc Lond B Biol Sci. www.bndu.ox.ac.uk/papers/hippo... @ndcnoxford.bsky.social @ox.ac.uk

New perspective paper from our lab: “The hippocampus as a generative model” out now !! royalsocietypublishing.org/rstb/article... The traditional view of the hippocampus is that it creates a cognitive map. Here we extend this view to conceptualise the hippocampus as a “generative model”.

The hippocampus as a generative model

Abstract. A generative model can be defined as a model of the latent causes of sensory input that can be used to generate new data samples. By examining em

royalsocietypublishing.org

It was a pleasure to be able to contribute to this exciting special issue with @sumedhanalluru.bsky.social @glitzleonie.bsky.social @xenianeuro.bsky.social and Valentina Mancini. Thanks to @peterkok.bsky.social @mariamaly.bsky.social @barense.bsky.social for putting it together!

Peter Kok@peterkok.bsky.social · 4w ago

The hippocampus sits at the interface of perception & memory, allowing us to link past, present, & future through its role in generating predictions. Excited to share this theme issue in @royalsociety.org's Philosophical Transactions B, co-edited with @barense.bsky.social & @mariamaly.bsky.social

How do brains plan actions towards goals? To get at this question we studied mice navigating complex mazes as goals changed on every trial 🧵 Work with @thomasakam.bsky.social @behrenstimb.bsky.social @kristorpjensen.bsky.social now on BioRxiv: www.biorxiv.org/content/10.6...

*** New paper from the lab in Nature Comms !! *** “Noradrenaline causes a spread of association in the hippocampal cognitive map” by the amazing @reneecabbage.bsky.social in collab. w labs of Jill O’Reilly, Will Clarke, and modeling from Prakriti Parthasarathy and @tpvogels.bsky.social, see below!

Renée Koolschijn@reneecabbage.bsky.social · 5mo ago

Very pleased to share that our study “Noradrenaline causes a spread of association in the hippocampal cognitive map” is out in @natcomms.nature.com (my final PhD paper, only 3.5 years post PhD! 🙃) Find the paper here: www.nature.com/articles/s41...

Very pleased to share that our study “Noradrenaline causes a spread of association in the hippocampal cognitive map” is out in @natcomms.nature.com (my final PhD paper, only 3.5 years post PhD! 🙃) Find the paper here: www.nature.com/articles/s41...

At #cosyne2026? Check out Sumedha Nalluru’s poster from our lab! Showing that reduced cortical inhibition causes false associations. Friday 13th March from 1:15 - 4:15pm.

Interested in cognitive maps? Wondering how you should best train your participants? Luckily for you, we have investigated just that! Very excited to share a preprint from my PhD in which we show how initial training curriculum affects the cognitive maps we form osf.io/preprints/ps... [1/6]

Out today in Neurophotonics, we show that cross-talk between the imaging laser and opsin in all-optical experiments can affect response dynamics beyond what has been accounted for. Imaging conditions subthreshold for evoking spikes can accelerate opsin desensitization: doi.org/10.1117/1.NP...

🎉 My PhD work has just been published in @natcomms.nature.com! How do we learn who caused what - and how much control we had - when outcomes depend on multiple people? We studied how humans do so using a new social learning task, computational modelling and fMRI. www.nature.com/articles/s41... 🧵👇

1/ Excited to share that our symposium review covering cognitive mapping in the PFC just came out in the Journal of Neuroscience: www.jneurosci.org/content/45/4...

Cognitive Maps in the Prefrontal Cortex

The prefrontal cortex (PFC) is critical for our ability to rapidly and flexibly adapt our behavior in new environments based on our previous experience. Despite its importance, the neural substrates a...

jneurosci.org

** We have up to TWO funded PhD positions available in our lab!! Apply below to find new ways to enhance memory👇 Pls retweet ** Deadline: 2nd December 1. Cross-species closed-loopTMR: tinyurl.com/bddu4tp6 2. TUS and TMR in humans: tinyurl.com/jjws5ctj Happy to chat to interested applicants.

I’m pleased to share our new paper, “Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain”, out in @cp-neuron.bsky.social ! With @vitorlds.bsky.social and David Dupret, we show that diversity in ripple current profiles shapes reactivation dynamics

I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time! www.biorxiv.org/content/10.1...

New unit paper on “Predictive coding model detects novelty on different levels of representation hierarchy”, published in Neural Computation. www.mrcbndu.ox.ac.uk/papers/predi... @mrcbndu.ox.ac.uk @ndcnoxford.bsky.social @ox.ac.uk

I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social ! With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding. (1/13)

Our study using layer fMRI to study the direction of communication between the hippocampus and cortex during perceptual predictions is finally out in Science Advances! Predicted-but-omitted shapes are represented in CA2/3 and correlate specifically with deep layers of PHC, suggesting feedback. 🧠🟦

Communication of perceptual predictions from the hippocampus to the deep layers of the parahippocampal cortex

High-resolution neuroimaging reveals stimulus-specific predictions sent from hippocampus to the neocortex during perception.

science.org

Happy to share the latest version of our work on compositional maps in hippocampus with Jo Warren, @jcrwhittington.bsky.social, @behrenstimb.bsky.social. We propose hippocampus constructs maps from cortical building blocks in replay – now with empirical support! www.nature.com/articles/s41... 1/9

Constructing future behavior in the hippocampal formation through composition and replay - Nature Neuroscience

A model of compositional state spaces in the hippocampus shows latent learning and rapid generalization. Bakermans et al. show that this model predicts the emergence of place responses in replay.

nature.com

New preprint out with @summerfieldlab.bsky.social! When does new learning interfere with existing knowledge? We compare continual learning in humans and artificial neural networks, revealing similar patterns of transfer & catastrophic interference (1/8) osf.io/preprints/ps...

We are currently building the largest, cross-domain data set of human behavior as part of an open collaborative project. Contributions of any form are welcome, but especially experiments with meta-data from developmental, cross-cultural, or clinical studies. More details: github.com/marcelbinz/P...

GitHub - marcelbinz/Psych-201

Contribute to marcelbinz/Psych-201 development by creating an account on GitHub.

github.com

Our paper "Memory reactivation generates new, adaptive behaviours that reach beyond direct experience" is now out www.nature.com/articles/s41...! With Annie Rawson, Jill O’Reilly and Helen Barron at MRC BNDU @ndcnoxford.bsky.social 1/6