Sakari Vanharanta
@svanharanta.bsky.social
Sigrid Jusélius Professor, Translational Cancer Medicine Program & Department of Biochemistry and Developmental Biology, University of Helsinki, Finland. #cancer #genomics #transcription #chromatin
New issue of Annual Reviews of Cancer Biology is out! www.annualreviews.org/content/jour...
Annual Review of Cancer Biology | Annual Reviews
AIMS AND SCOPE OF JOURNAL: The Annual Review of Cancer Biology reviews a range of subjects in cancer research that represent important and emerging areas in the field. With recent advances in our unde...
annualreviews.org
Very interesting work on the role of germline genetics in somatic tumor evolution.
Sarah Aitken@s-j-aitken.bsky.social · 2y ago🌟NEW PREPRINT ALERT!🌟 We are very pleased to introduce #StrainDifferences: “Genetic background sets the trajectory of cancer evolution” www.biorxiv.org/content/10.1... 🧵[1/12]
Last few days to apply👇! In addition to hot science, our campus offers refreshing dips within walking distance 💪🏖️ #BalticSea #Helsinki
Adaptmet@adaptmet.bsky.social · 2y ago📢 Calling all future cancer researchers! Adaptmet is offering 16 MSCA PhD positions in cutting-edge metastasis research. Follow this thread & get to know the exciting projects on offer among Europe’s best teams from top host institutions! More details 👉https://adaptmet.eu/recruitment/
Looking for a PhD? Follow this🧵 to know how Adaptmet's innovative training will combine continuous training in cutting-edge metastasis research with custom-made network-wide events to enhance, accelerate & elevate the skills, capacities & network of our doctoral candidates (DCs)
🧪1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇 www.nature.com/articles/s41...
Engineered extrachromosomal oncogene amplifications promote tumorigenesis - Nature
Large extrachromosomal DNAs are engineered using a CRISPR- and Cre–loxP-based approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene a...
nature.com
Today we published a new paradigm to do CRISPR screens in complex model systems such as in vivo but also e.g. in organoids. The publication came out in Nature Biotechnology. 1/ www.nature.com/articles/s41...
CRISPR-StAR enables high-resolution genetic screening in complex in vivo models - Nature Biotechnology
Pooled genetic CRISPR screening is improved in complex models through leveraging internal controls.
nature.com
aacrjournals.org/cdnews/news/...
Inherited Gene Variant Tied to Breast Cancer Spread
A common germline variant of PCSK9 significantly increases the risk of breast cancer metastasis, a new study has revealed. The finding—a first example of inherited genes driving metastatic progression...
aacrjournals.org
Very interesting insight into tumor-immune interaction under chemotherapy in ovarian cancer. Congrats Anniina, Anna and the teams!
Färkkilä Laboratory@farkkilab.bsky.social · 2y ago1/n New paper alert 🚨 We're thrilled to share our just published paper in #CancerCell Do you ever wonder how the #TME in #HGSC changes during chemotherapy? Check it here: www.sciencedirect.com/science/arti... and let’s dive into the highlights together #spatialbiology #ovariancancer #cancerresarch
New in @natureportfolio.bsky.social from the Tuomas Tammela Lab: how aging suppresses tumorigenesis and stemness in the lung by promoting functional iron insufficiency in the alveolar epithelium. Interestingly, this renders aged cells resistant to ferroptosis. #OncSky www.nature.com/articles/s41...
Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis - Nature
Studies using mouse models of lung adenocarcinoma identify an association between age, iron homeostasis and tumour initiation potential that involves NUPR1 and lipocalin-2.
nature.com
Inflammatory monocytes can restimulate T cells in tumors, and cancer cell-induced disruption of this process can lead to tumor immune evasion. Details 👇 in the wonderful 🧵 by @obenaufa.bsky.social and the paper published today @Nature. What a privilege it has been to be part of this amazing team!
Anna Obenauf@obenaufa.bsky.social · 2y ago1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...
Hello Bluesky, we are recruiting PhD students in cancer and metastasis biology! This is a fantastic program that brings together several leading European research institutes. Details here: adaptmet.eu/recruitment/
Recruitment
Recruitment is now open! Apply for one of the 16 positions availablein the Adaptmet network and build your futureas a researcher in metastasis! Adaptmet is offering generous three-year fellowship...
adaptmet.eu
