theNiessingLabs
@theniessinglabs.bsky.social
We use structural biology, biochemistry, and (stem) cell biology to understand the roles of RNA-binding proteins in neurodevelopmental #PURA Syndrome and neurodegeneration. We are located at @uniulm.bsky.social and at @helmholtzmunich.bsky.social, Germany.
What a wonderful evening celebrating 20 years of the Niessing Labs! 🧬🥂 Great to reconnect with former lab members, celebrate current projects, and look back on two decades of exciting science. Here’s to many more discoveries ahead! ✨ #NiessingLabs #20Years #LabLife #Science
My name is Simi. For more than 10 years, I have been working at the Munich research group, where I handle all administrative tasks and, have also been responsible for the PURA Biobank at the Helmholtz Munich. I earned my degree in biology from LMU and I am thrilled to be part of this great team 🙂
Representing the Niessing labs at this year's B2Run as part of the Helmholtz Munich team! A great evening of running, team spirit, and fun outside the lab. Looking forward to the next one! 🏃♀️ #B2Run #HelmholtzMunich
Representing the Niessing labs at this year's B2Run as part of the Helmholtz Munich team! A great evening of running, team spirit, and fun outside the lab. Looking forward to the next one! 🏃♀️ #B2Run #HelmholtzMunich
Meet the faces behind the science🔬 Over the next weeks, we’ll introduce each member of our team. Starting off with Manu “Hi ☺️ I am the technician at the Ulm labs. I’ve been in this group for almost 5 years. I did my master degree in Biology and spend some time doing field work in South America“ #lab
This past weekend at the PURA Conference in Munich reminded us what makes rare disease research so special: bringing together families, clinicians, and researchers from around the world. We were honored to receive the PURA Hero Award 2026. #Purafoundation #community #purasyndrome #Rare #TeamPURA
We are excited to share our new preprint: iCLIP3 — an improved protocol for transcriptome-wide mapping of protein–RNA interactions at single-nucleotide resolution.
bioRxivpreprint@biorxivpreprint.bsky.social · 5mo agoiCLIP3: A streamlined, non-radioactive protocol for mapping protein-RNA interactions in cellular transcripts at single-nucleotide resolution https://www.biorxiv.org/content/10.64898/2026.03.01.708747v1
Searching for a human neural cell line with greater differentiation potential than SH-SY5Y cells? Check out the human #neural #stem_cell line HNSC.100. Differentiates into astrocytes, neurons & oligodendrocytes. On #BioRxiv, we provide protocols, markers, ABs, karyotyping & RNAseq: shorturl.at/y0aJG
Merry Christmas and Happy New Year to all of you! 🎄
Von Bio-inspirierten Technologien über medizinische & gesellschaftliche Herausforderungen bis hin zur Neurochirurgie spannt sich der Bogen der Vortragsreihe der Ulmer Universitätsgesellschaft. Eintritt frei!🆓 t1p.de/uug_33 *stg #uulm
We are so grateful! PURA Syndrome Deutschland e.V. makes donation to support our research on #PURA syndrome at @helmholtzmunich.bsky.social, #Rare #puraperfect.
Had an exciting visit to the German University in Cairo (www.guc.edu.eg). I was impressed by how much this university contributes to mutual understanding between Europe and the Middle East through academic exchange. Much needed these days! Close collaboration with #UUlm and supported by #DAAD.
Today we launched the #PURA Biobank at @www.helmholtz-munich.de for patients with #purasyndrome. Biosamples will support research and development of treatment strategies. Big thanks to PURA Syndrome Foundation USA for your constant support! #Rare #puraperfect www.helmholtz-munich.de/en/pura-biob...
Great collaboration of Simone Heber and Anne Ephrussi with our lab on Staufen-dependent RNA localization!
Hennig-Lab@hennig-lab.bsky.social · last yr.If you are interested in cellular RNA transport, check out Simone Heber's first corresponding author paper: www.cell.com/cell-reports... Very cool stuff about motor switching to get the transport direction right. Collaboration between the Ephrussi, Niessing. Hennig, Chao and Heber groups.
www.biorxiv.org/content/10.1...
Perturbing RNA localization for functional study in neurons
Spatial RNA organization plays a pivotal role in diverse cellular processes and diseases, but the functional implications of spatial RNA localization remain underexplored. We present CRISPR-mediated t...
biorxiv.org
We participated in Interact Munich 2025, where we had the opportunity to present our research through posters, connect with fellow young researchers, and attend inspiring talks. A big thank you to the organizing team for making such a fantastic event possible! #interact2025
Lab work is important but also consumes lots of energy and resources. We are the first lab at @www.helmholtz-munich.de to be awarded with the Gold level LEAF (Laboratory Efficiency Assessment Framework) certificate of the @ucl.ac.uk for our efforts to become a more sustainable laboratory!
Terrified by the global developments and current politics? We took a break from the world by attending a hip-hop dance class. Lots of excitement, confusion, and happiness. We can highly recommend it as a mental therapy...
🚨 Early Bird Registration Closing Soon for Interact Munich 2025! 🚨 ⏳ Don’t miss out! Our Early Bird pricing for Interact Munich 2025 ends on February 17th – secure your spot today and save on registration!
Check out our recent work on CDS #m6A mediated RNA decay (CMD)! Decay relies on ribosome pausing at m6A containing codons. Great collab with the Zarnack lab & colleagues. Thank you @uniwuerzburg.bsky.social , @imbmainz.bsky.social and RMap🥳 www.cell.com/molecular-ce...
Now out on bioRxiv: our collaboration with Simone Heber, Anne Ephrussi and Jeff Chao reveals how Staufen interacts with the kinesin adapter aTm1 to localize oskar mRNA in #Drosophila oocytes, modulating kinesin-1 dependent mRNA transport. #RNAsky #RNA doi.org/10.1101/2024...
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month. We are very grateful for his service. @jiwasa.bsky.social will continue the series, beginning with January's article on Assembly Line Polyketide Synthases Details: cdn.rcsb.org/rcsb-pd...
EDUCATION CORNER: Molecule of the Month: Celebrating 25 Years of Storytelling and Announcing New Beginnings
After a remarkable 300 columns, David Goodsell has retired from the Molecule of the Month series. Janet Iwasa will be continuing the series for PDB-101.
cdn.rcsb.org
🌟 Welcome to <interact> 2025 🌟 We’re thrilled to announce the most exciting student-organised scientific conference is back in 2025! 🎉 📅 Mark your calendars: 🗓️ April 3-4, 2025 📍 Venue: Biomedical Center (BMC), LMU Munich
Hello Bluesky 🤠 Our very first post is about our recent paper in Nucleic Acids Research: so-called PUN motifs are repetitive elements enabling proteins to catalyze #RNA folding and RNA-dependent #condensate formation ( #LLPS). 15% of human proteins contain 3 or more PUN motifs. See bit.ly/4fZ3f54.
