Only 1 week left to register for the RNA 3' ends processing meeting, come one, get a wiggle on!! meetings.embo.org/event/26-rna3

Latest from GN's out! Sequence specificty of Restrictors been determined, lovely stuff :D

Molecular Cell@cp-molcell.bsky.social · 6mo ago

Online Now: Sequence-specific RNA recognition drives Restrictor-mediated termination of extragenic transcription Online now:

Surely THIS is the most important #RNA conference of the year?!?!? In beautiful oxford!

EMBO@embo.org · 8mo ago

Discuss #RNA 3' ends and their regulation at the EMBO Workshop "RNA 3' ends and beyond" in #Oxford, United Kingdom, 7–11 September 2026. Deadline: 4 May 2026 https://meetings.embo.org/event/26-rna3 #EMBORNA3EndsBeyond #RNAsky #LifeSciences #meeting #EMBOevents 🧪

Love me a supplementary mass spec excel spreadsheet! Had a look at the ARS2 IP-MS, su(s) is one of the top hits!! More evidence L searles was right and su(s) is the fly orthologue of ZC3H4

Cell Reports@cp-cellreports.bsky.social · 11mo ago

Defining the roles of the Integrator, NEXT, and nuclear exosome complexes in Drosophila oogenesis

Ding ding! New Restrictor paper out showing that ZC3H4 affects transcription universally at a checkpoint downstream and distinct to Integrator! Sequential verification of transcription by Integrator and Restrictor: Molecular Cell www.cell.com/molecular-ce...

Sequential verification of transcription by Integrator and Restrictor

Estell and Łazowski et al. show that Integrator and Restrictor form distinct pathways for early attenuation of RNA polymerase II: Integrator acts at the promoter-proximal pause site, whereas Restricto...

cell.com

Well this is shit :(

Benoit Bruneau@benoitbruneau.bsky.social · last yr.

shocking to read over and over the stories of close colleagues who can't run their lab anymore. I know Karen well and it's heartbreaking. Also #PIinthelab! www.washingtonpost.com/education/20...

The Vlaming lab is expanding! If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat... My biased opinion: exciting topic, super nice colleagues, and great research environment in a lovely city.

PhD position in Gene Regulation

Are you excited about studying the crucial process of transcription? Join our supportive, young and growing team!

uu.nl

New paper on the consequences of ZC3H4 loss, looking at Transcription-replication clashes www.science.org/doi/10.1126/...

ZC3H4 safeguards genome integrity by preventing transcription-replication conflicts at noncoding RNA loci

A protein that suppresses noncoding RNA emerges as a guardian of genome stability.

science.org

Very excited that our paper describing a critical role for the PNUTS-PP1 phosphatase complex in transcription pause release is up online! This was a massive team effort with @edimitrova.bsky.social and the rest of the @robklose.bsky.social lab www.cell.com/molecular-ce... A short thread: (1/8)

The PNUTS phosphatase complex controls transcription pause release

Kelley et al. discover that the PNUTS phosphatase complex plays an essential role in gene transcription by controlling RNA polymerase II pause release. PNUTS achieves this through its TND, which recog...

cell.com

Great summary by @triggerloop.bsky.social for JMBs special on transcription!

Craig Kaplan@triggerloop.bsky.social · 2y ago

As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...