🚨 Ever wonder why some viral reassortants establish and spread while others disappear? Us too! Led by @ricardoriveroh.bsky.social, we studied drivers of viral reassortment across hantaviruses and found that it varies dramatically among lineages (1/3) Preprint: doi.org/10.64898/202...

CANSAÇO? | Quem usa bebidas com cafeína para compensar noites mal dormidas pode estar se predispondo à enxaqueca. Experimento com ratos do Laboratório de Farmacologia da Dor Orofacial da UFPR produziu informações recentes sobre esse hábito. Leia em ciencia.ufpr.br/portal/?p=29... #DCBR #cienciabr

In our most recente study, we report a case of fatal equine encephalitis caused by Rocio virus. We isolated the virus and sequenced its full genome, revealing that it is still circulating in nature and may re-emerge from its elusive sylvatic cycle. link.springer.com/article/10.1...

Rocio virus sustained circulation in Brazil: first infection case in a horse highlights the need for enhanced arbovirus surveillance - Archives of Virology

Archives of Virology - Rocio virus (ROCV), a neurotropic arbovirus of the Orthoflavivirus genus, caused Brazil’s largest encephalitis outbreak in the 1970s but has since been rarely detected....

link.springer.com

🦟 Dengue virus serotype 3 (DENV-3) has re-emerged in Brazil after ~15 years of low circulation. We combined genomic and epidemiological data to assess its spread and public health impact. 🧵⬇️ papers.ssrn.com/sol3/papers....

Two cases of Middle Eastern Respiratory Syndrome (MERS), a dangerous viral infection, detected in France in travellers from the Arabian Peninsula. Another reminder that our world is deeply interconnected & vigilance for imported infections is essential. tinyurl.com/4mdhwfdz

Researchers found evidence that common vampire bats living along Peru’s coast were exposed to H5N1 during a massive outbreak of the virus that started in late 2022. https://scim.ag/4pyxuob

Vampire bats may have contracted H5N1 bird flu in Peru, raising worries about further spread

Bats could form a bridge between marine and terrestrial mammals, scientists say

scim.ag

Happy Thanksgiving everyone. I will keep it short and sweet. Great news out of Brazil today 👇. Congratulations to the interdisciplinary teams that made it a reality! @mauriciolnogueira.bsky.social @astmh.bsky.social #Burantan

New paper on climate variation and the importance of considering serotype competition in dengue dynamics, with @emiliefinch.bsky.social @drrachellowe.bsky.social and others www.nature.com/articles/s41...

Since the topic of the moment is the new betacoronavirus with FCS found in Brazil, I would like to draw attention to this preprint. It describes two new betacoronaviruses found in the same genus of bats as Takada et al, and propose a new subgenus, the ambecoviruses. www.biorxiv.org/content/10.1...

Ambecovirus, a novel Betacoronavirus subgenus circulating in neotropical bats sheds new light on bat-borne coronaviruses evolution

Understanding the viral diversity harboured by wildlife is essential for effective prediction and prevention of future zoonotic outbreaks. Bats, in particular, are recognized as natural reservoirs for...

biorxiv.org

“Furin cleavage site”, that is. Just casually, and naturally, sitting there in one of the most evolutionarily active parts of the genome. Mystery solved.

Greg Folkers@gregfolkers.bsky.social · 9mo ago

CIDRAP: New coronavirus subspecies with SARS-CoV-2–like mutation discovered in Brazilian bat by Mary Van Beusekom @cidrap.bsky.social bit.ly/4hHRfam

We’ve identified a highly divergent betacoronavirus from South American bat that encodes a functional furin cleavage site. Another fascinating reminder of how diverse coronavirus evolution is in wildlife reservoirs. #Virology #VirusEvolution #Bats #Coronavirus www.biorxiv.org/content/10.1...

A divergent betacoronavirus with a functional furin cleavage site in South American bats

Bats are natural reservoirs for a wide range of RNA viruses. Members of the genus Betacoronavirus, including Severe Acute Respiratory Syndrome virus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome...

biorxiv.org

www.bbc.com/portuguese/a...

Inteligência artificial: a brasileira em lista dos 100 mais influentes de IA que oferece solução gratuita ao SUS — 'Nunca quisemos ser milionários' - BBC News Brasil

Ana Helena Ulbrich aparece em lista da revista Time ao lado de líderes como Elon Musk e Sam Altman.

bbc.com

Viro3D paper is out! We predicted 85,000 protein structures from human & animal viruses. 1/5 🧵 📑 Paper doi.org/10.1038/s443... 🔭 Explore virosphere viro3d.cvr.gla.ac.uk

Viro3D: a comprehensive database of virus protein structure predictions | Molecular Systems Biology

imageimageViro3D provides proteome-level, high confidence AI-protein structure predictions for >4,400 viruses, allowing mapping of form and function across the human and animal virosphere. Viro3D i...

doi.org

📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬 Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨ Key findings in thread below 👇 www.biorxiv.org/content/10.1...

Heterogeneity in inhibition of genetically diverse dengue virus strains by Wolbachia

The release of Aedes aegypti mosquitoes transinfected with the virus-inhibiting Wolbachia bacterium has the potential to reduce the burden caused by dengue virus (DENV). However, the robustness of thi...

biorxiv.org

Confused writing is usually a symptom of confused thinking. As we struggle to clarify writing, we clarify our thoughts. AI writing aids rob us of that struggle, leaving clean-looking text and thoughts still confused for lack of inspection. Writing is not just a product; it is a diagnostic tool.

Sequence data from the new Ebola outbreak in DRC suggests it is indeed a new spillover. And just incredible to see the virus sequenced and the data publicly shared less than 24 hours after confirmation of the outbreak. #IDsky 🧪 virological.org/t/the-16th-e...

The 16th Ebola Virus Disease Outbreak in Bulape Health Zone, Kasai, Democratic Republic of the Congo: A new spillover event from an unknown reservoir host

Background The Democratic Republic of the Congo (DRC) is currently facing concurrent outbreaks including mpox, cholera and malaria (1-4). The Ministry of Public Health, DRC has declared the 16th Ebola...

virological.org

I’m thrilled to share my first review about microbial ecology + mosquito-borne disease control! Bacteria block pathogen development in the mosquito gut, but which bacteria will produce long-lasting results in the field? Let’s think about colonization and persistence in the mosquito gut! (1/4)

Trends in Parasitology@cp-trendsparasitol.bsky.social · last yr.

Drs @holly-nichols.bsky.social‬ & Kerri Coon review #microbial #ecology for #mosquito-borne disease control. #Paratransgenesis #Colonization #Resistance #Transmission #Microbiota #Transplantation @uwbact.bsky.social‬ ‪@uwmadisonmdtp.bsky.social‬ @uwmadison.bsky.social www.cell.com/trends/paras...

Handy to keep up with the ICTV's changes to virus taxonomy and species names: taxonomy.onecodex.com/taxon/694009... vs: taxonomy.onecodex.com/taxon/694009... or taxonomy.onecodex.com/taxon/11676/... vs taxonomy.onecodex.com/taxon/11676/...

Austin Richardson@agdr.org · 2y ago

NCBI's Taxonomy changes over time. We built Taxonomy Time Machine to track these changes: 🕰️ app: taxonomy.onecodex.com 📄 pre-print: www.biorxiv.org/content/10.1...

Provavelmente os casos brasileiros de HPAI em 2025 devem ser devido a esta nova linhagem recombinante. Muito importante sequenciar e analisar o genoma do vírus circulando atualmente no país.

Michelle Wille@duckswabber.bsky.social · last yr.

Novel reassortant H5N1 w gene segments from Eurasian H5N1 + LPAI South + North American lineages from poultry (chickens/ducks) in Argentina in Feb 2025. 👉 www.biorxiv.org/content/10.1...

A not very happy Friday. CERI had 6 NIH grants canceled, which will impact operations, surveillance and response to epidemics. We are working to try to minimize disturbance but not easy with 6 grants terminated at the same moment. A crisis is unfolding in SA www.news24.com/southafrica/...

SA universities face funding crisis as US federal agencies freeze research grants | News24

An investigation into the impact of the US aid freeze on research funding to South African universities has found that 44 programmes worth R2.5 billion were affected.

news24.com

Frustrated that MCMCtree does not have complex substitution models? The IQ-tree team has now developed IQ2MC, an interface for seamless integration of IQ-tree's substitution models with MCMCtree's fast Bayesian pipeline for clock dating. Read the preprint here: ecoevorxiv.org/repository/v...

🦟🦠 NEW! We looked at every experiment going back to the 1960s, and found that mosquitoes are almost certainly not primary or secondary vectors of Oropouche virus - a common claim in both the scientific literature and public health communication. #EpiSky #IDSky 😷🧪 journals.plos.org/plosntds/art...

Vector competence for Oropouche virus: A systematic review of pre-2024 experiments

Oropouche virus has recently become an urgent threat to public health in Central and South America. OROV is mainly transmitted by biting midges; however, some public health agencies and scientific sou...

journals.plos.org

We celebrated the 100th anniversary of HR Carter's seminal lecture on YF's potential threat to Asia-Pacific area with a perspective to draw attention to the potential reasons why YF epidemics have not occurred in urban centers in the region. @sbvirologia.bsky.social @mauriciolnogueira.bsky.social

“Funding by the CDC for two monthly peer-reviewed journals, Emerging Infectious Diseases and Preventing Chronic Disease, will be cut.” EID has published novel, important work that brings #IDSky issues to light. Its loss will hurt.

Miranda Yaver@mirandayaver.bsky.social · last yr.

This is a very helpful breakdown of the devastating outline of HHS cuts and reorganization. www.fiercehealthcare.com/regulatory/h...

Our latest preprint demonstrates that two strains of DENV4 have distinct impacts on Aedes aegypti vector competence and life-history traits. www.biorxiv.org/content/10.1...

A Laboratory-Adapted and a Clinical Isolate of Dengue Virus Serotype 4 Differently Impact Aedes aegypti Life-History Traits Relevant to Vectorial Capacity

Dengue virus cases are on the rise globally, and strategies to reduce new infections by controlling its primary vector, the mosquito Aedes aegypti , represent a promising biotechnological approach. Ho...

biorxiv.org

On the verge: outbreak risk after two years of record-breaking dengue epidemics in Brazil - The Lancet Regional Health – Americas www.thelancet.com/journals/lan...

On the verge: outbreak risk after two years of record-breaking dengue epidemics in Brazil

Over the last seasons of dengue, the disease has reached record-breaking numbers of confirmed cases both globally and in the Americas.1 That is speculated to be a consequence of two-fold climate drive...

thelancet.com

Hantavirus: Global emerging disease with 2 major syndromes Hantavirus Pulmonary Syndrome (HPS) – Americas: 130 cases/year, 30-60% mortality, depending on type Hemorrhagic Fever with Renal Syndrome (HFRS) – Asia/Europe: 100K cases/year, 5-10% fatality rate Spread by rodents primarily 🧵

This is my first post here and I would like to share this important work that I collaborated on. We analyzed some of the factors impacting the spread of dengue in the Brazilian southern most state, where outbreaks are getting larger each year. www.medrxiv.org/content/10.1...

Increasing dengue outbreaks in temperate Brazil is linked to Aedes aegypti invasion and infestation level driving widespread virus transmission

Dengue fever, caused by the dengue virus (DENV), is the most important mosquito-borne disease impacting human health globally, it is particularly prevalent in tropical regions where Aedes vectors thri...

medrxiv.org

PLOS has issued a statement on recent US Executive Orders and scientific integrity. We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry. plos.io/3D4O8cH

PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog

Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…

plos.io

I have insomnia a lot lately so may as well share what’s literally keeping me up at night. It’s a long list but tonight it’s flu. Yes, H5N1, but also seasonal flu. Firing federal scientists brings a flu-filled future. Have you ever wondered how flu vaccine strains are chosen?