🧠 New paper accepted in Neuropsychologia! Dysfunctional neural processing of object-related speech in schizophrenia spectrum disorders — and a potential compensatory role of congruent tool-use gestures? Great work led by Katrin Leinweber! #Schizophrenia #fMRI #Gesture doi.org/10.1016/j.ne...

📢 Wir suchen Verstärkung! Neue Promotionsstelle (3 Jahre, 65 %, E13) in unserer Arbeitsgruppe zu affektiven & Angststörungen, Erwartungen und Lernen. 🧠 fMRT & EEG 🤝 SFB/TRR 393 + DFG-Projekt Angststörungen 📅 Bewerbung bis 27.09.2026 stellenangebote.uni-marburg.de/jobposting/4... Gerne teilen!

Expectations matter—not only for how we act, but also for mental health. 🧠 Our new study shows that negative expectations in major depression are linked to brain structure and predict illness course over two years—complementing our recent #ExSA framework. doi.org/10.1016/j.ja... #Expectations

A new conceptual framework linking predictive processing, motor control, reinforcement learning, and clinical neuroscience. The ExSA framework explains how expectations shape action and provides a framework for dissociating mechanisms underlying action dysfunction.

Benjamin Straube@straubeb.bsky.social · 3mo ago

Now available in Trends Open: How do expectations shape actions? I introduce the ExSA framework, integrating perspectives from motor control, decision-making, predictive processing, and clinical neuroscience Read here: www.cell.com/trends-open/... #Psychology #MotorControl #PredictiveProcessing

How does attention shape what we perceive—and does this differ in schizophrenia spectrum disorders? Here our new findings: rdcu.be/fr3sm #Schizophrenia #Psychiatry #Neuroscience #Attention #Perception #CognitiveNeuroscience

🚨 Permanent position! theadaptivemind-excellencecluster.de is looking for a managing director of our new outreach hub. This is an unlimited time position at an E13 paygrade (~postdoc level) Apply by May 31st 👉 www.career.tu-darmstadt.de/tu-darmstadt... Please share widely 🙏

📍DYNAMIC Symposium at the Psychology and Brain Conference 2026 Researchers from the LOEWE Center DYNAMIC attended the Psychology and Brain Conference, which took place in Heidelberg from June 3 to 6. ➡️ Read more: www.dynamic-center.net/announce-202...

DYNAMIC Symposium at the Psychology and Brain Conference 2026

Participation from LOEWE-DYNAMIC Researchers in the Psychology and Brain Conference 2026

dynamic-center.net

Very happy that our manuscript with my brilliant collaborators @jamestrujillo.bsky.social and @straubeb.bsky.social is now published @jneurolang.bsky.social. 🥳🥳🥳 Interested in gesture, discourse, fMRI, prediction, computational modeling? This is the paper for you 👇 doi.org/10.1162/NOL....

Discourse context and co-speech gestures jointly shape hierarchical prediction during the processing of a multimodal narrative

Abstract. Understanding one another in daily communication depends on predicting language from prior discourse context and visual signals, such as co-speech gestures. However, it remains unclear how d...

doi.org

James Trujillo @jamestrujillo.bsky.social · 2y ago

When listening to a story, earlier parts of the story (context) and the speaker's gestures help us predict and understand what they are saying. In a new preprint we show context and gestures have a push-pull synergy on neural response to linguistic information 👇🧵

New paper in Scientific Reports: Using HRF temporal and dispersion derivatives, we show altered preparatory neural timing in SSD, particularly during self-generated action processing. www.nature.com/articles/s41... #Schizophrenia #fMRI #SenseOfAgency

New manuscript: From Expectation to Learning: A Mediational Model of Exposure Therapy Outcome in Anxiety Disorders We propose a hierarchical pathway: generalized expectations → treatment-specific expectations → learning rate during exposure → clinical outcome. doi.org/10.1159/0005... #Expectation

From Expectation to Learning: A Mediational Model of Exposure Therapy Outcome in Anxiety Disorders

Abstract. Introduction: Negative expectations about treatment outcomes are associated with poorer recovery in anxiety disorders. However, it remains unclear whether (1) patients’ expectations about how effective the treatment will be (treatment-specific expectations) mediate the link between generalized negative expectations (i.e. unspecific pessimistic beliefs) and treatment outcomes, and (2) these expectations affect outcomes via the learning rate during exposure therapy, that is, the extent to which patients update their fear-related beliefs based on corrective experiences. Since treatment-specific expectations may be more modifiable, clarifying these mechanisms could improve interventions. This study investigated whether treatment-specific expectations and learning rate mediate the effect of generalized negative expectations on treatment outcomes. Methods: Data from 605 patients with various anxiety disorders undergoing 12 sessions of manualized exposure therapy were analyzed. Generalized negative expectations at baseline (session 0) were hypothesized to predict treatment outcomes (i.e., symptom severity at post treatment) via expectations about treatment success measured at session 4 and learning rate during exposure. Depression and anxiety at baseline were covariates. Mediation analyses were conducted using the PROCESS macro with bootstrap confidence intervals. Results: Generalized negative expectations predicted poorer treatment outcomes (higher symptom severity), mediated by lower expectations about treatment success (β = 0.0375; 95% CI: 0.0088–0.0730). A sequential mediation via these treatment-specific expectations and learning rate was also significant (β = 0.0059; 95% CI: 0.0008–0.0134), even after accounting for baseline symptom levels (R² = 0.3375). Conclusion: Targeting both generalized and treatment-specific expectations early in treatment may enhance exposure-based learning and improve clinical outcomes in anxiety disorders.

doi.org

New work from the lab led by @fatatai.bsky.social together with Dimitris Voudouris, @dominikstrb.bsky.social, Katja Fiehler as part of 'The Adaptive Mind' cluster

Fabian Tatai@fatatai.bsky.social · 8mo ago

Why is touch perceived as weaker during movement? In our new preprint 📝, we examine tactile suppression during reaching. Using optimal control theory, we show that tactile suppression reflects dynamic, uncertainty-dependent integration of forward model predictions and sensory feedback.

We're looking for a student assisten (HIWI) in the TNM Lab!!! www.uni-marburg.de/de/universit...

📣📣📣Job alert Multimodal Language Department Max Planck Institute for Psycholinguistics MAX PLANCK RESEARCH GROUP LEADER POSITION (W2 BBESG) lnkd.in/eaq5MW9a

How is genetic risk for inflammation linked to mental disorders? Our new study applies transdiagnostic network analysis to uncover symptom-level associations beyond categorical diagnoses. www.sciencedirect.com/science/arti...

Genetic predisposition to inflammation and psychopathology: A transdiagnostic network analysis

Although low-grade inflammatory processes have traditionally been studied in affective disorders, they are increasingly recognized as relevant across …

sciencedirect.com

I’m excited to announce that Bielefeld will soon (in 2026) be home to a research-dedicated 3-T MRI The scanner will be run as a central research core facility, and we’re seeking a scientific leader (TV-L E15, permanent) to help build and shape it. MR physicist ads to follow. tinyurl.com/mryhaxed

Leiter*in (m/w/d) der zentralen Core Facility MR I...

Mit der Entwicklung der zentralen, fakultätsübergreifenden Core Facility MR Imaging baut die Universität Bielefeld unter Beteiligung der Naturwisse...

uni-bielefeld.hr4you.org

📢Out now! @codingfisch.bsky.social and colleagues present deepmriprep, a tool that leverages neural networks to enable 37x faster Voxel-based Morphometry preprocessing of MRI data than existing methods. www.nature.com/articles/s43... #compneurosky

deepmriprep: voxel-based morphometry preprocessing via deep neural networks - Nature Computational Science

deepmriprep leverages neural networks to enable voxel-based morphometry preprocessing of MRI data that is 37× faster than existing methods while achieving comparable accuracy in segmentation, registra...

nature.com

"deepmriprep: VBM preprocessing via deep neural networks" is published in Nature Computational Science 🧠💻 🔗 Paper: rdcu.be/e1t4N VBM preprocessing in ~10 seconds per #brain image 🚀 🔗 GitHub: github.com/wwu-mmll/deepm… Install via "pip install deepmriprep"

How are mental representations formed, structured, and updated?👉 www.inlibra.com/de/document/... Dimensions of mental representations in psychiatry: An example from speech and gesture processing in schizophrenia doi.org/10.5771/0072-1492-2025-2-235 #CognitiveNeuroscience #MentalRepresentation

Investigating individual-specific topographic organization has traditionally been a resource-intensive and time-consuming process. But what if we could map visual cortex organization in thousands of brains? Here we offer the community with a toolbox that can do just that! tinyurl.com/deepretinotopy

During last week's retreat, we awarded #posterprizes to the best 3 of ~70 excellent #ECR posters. 🎉 Congratulations to winners Vera Ludwig, Alina Nostadt, Claudia Förster Ribet, Tung Anh Nguyen & Theresa Kolb - thank you to all ECRs for presenting your research and engaging in lively discussions!

New fMRI evidence shows altered neural dynamics in schizophrenia spectrum disorders: temporal recalibration of action-outcome predictions engages the middle frontal gyrus and cerebellum differently in patients vs controls. www.nature.com/articles/s41...

New evidence challenges a usual assumption of exposure therapy: instructed increases in fear activation during exposure did not enhance treatment outcomes for anxiety disorders (e.g., social anxiety/panic) www.sciencedirect.com/science/arti...

Instructed increase in fear activation during exposure exercises does not enhance treatment effects of cognitive behavioral therapy for panic disorder and agoraphobia

The efficacy of exposure-based cognitive behavioral therapy (eCBT) for panic disorder and agoraphobia (PD/AG) is well established, but the mechanisms …

sciencedirect.com

🧠 Our CRC/TRR 393 consortium outlines key mechanisms of affective disorders — focusing on emotion regulation, expectation, social cognition, and cognitive-behavioral rhythms. Read here 👉 doi.org/10.1007/s001... @kanske.bsky.social @markuswohr.bsky.social @lisaleehr.bsky.social @trr393.bsky.social

Key mechanisms of affective disorders - Der Nervenarzt

Background Although affective disorders are a major driver of disability worldwide, there is a lack of understanding of the mechanisms and modulating factors involved in the long-term disease trajecto...

doi.org

📣 The ENIGMA study “Regional brain morphology and current antidepressant use” explores how antidepressant medication correlates with structural brain differences in Major Depressive Disorder across age and sex, drawing on data from 32 international cohorts. 🧠 🔗 Read it here: doi.org/10.1038/s413...

Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group - Molecular Psychiatry

Molecular Psychiatry - Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group

doi.org

A new publication, “Transdiagnostic alterations in white-matter microstructure associated with suicidal thoughts and behaviours in the ENIGMA Suicidal Thoughts and Behaviours consortium”, by ENIGMA Suicidal Thoughts & Behaviours Consortium (Translational Psychiatry www.nature.com/articles/s41...)

🧠 New paper investigated how childhood maltreatment shapes structural brain connectivity across affective and psychotic disorders. Now out in European Neuropsychopharmacology: 🔗 authors.elsevier.com/sd/article/S... #Neuroscience #Psychiatry #BrainConnectivity #ChildhoodMaltreatment

😊 New publication! Joy Beyond Fear: Positive Emotions After Exposure in Patients with Anxiety Disorders and Their Link to Threat Expectancy and Treatment Outcome Now out in Behaviour Research and Therapy: 🔗 doi.org/10.1016/j.br... #AnxietyDisorders #ExposureTherapy #PositiveEmotions #Expectancy

🧩 New article! Same same but different: Threat expectancy change and fear reduction as readouts of exposure rationales are only weakly associated to treatment outcome in anxiety disorders Now published in Behaviour Research and Therapy: 🔗 doi.org/10.1016/j.br... #AnxietyDisorders #Expectancy

🧠Out now @natcomms.nature.com ! Brain changes linked to childhood maltreatment are among the field's most published findings. Yet, we find extensive replication failure of gray matter correlates in three large cohorts (N=3225), consistent across subsamples, models and operationalizations🧵

The CRC/TRR 393 aims to unravel trajectories of depression & bipolar disorder by combining mobile assessments, neuroimaging, -omics & interventions in >1500 participants. A 12-year effort to decode mechanisms of recurrence & remission. Overview: 🔗 rdcu.be/eGtBy