Traffic
@traffic-journal.bsky.social
onlinelibrary.wiley.com/journal/1600... Traffic is a cell biology and biochemistry journal devoted to intracellular transport in health and disease, covering disciplines such as developmental biology, neuroscience, immunology, and infection in eukaryotes.
Just Published! onlinelibrary.wiley.com/doi/10.1111/... @labsoap.bsky.social
Syntaxin 12 Sustains Endosomal‐Lysosomal Homeostasis and Survival in Glioblastoma Stem‐Like Cells
Syntaxin12 maintains endolysosomal trafficking and lysosomal homeostasis in glioblastoma cells. Syntaxin12 depletion disrupts lysosomal organization, impairs endolysosomal progression and mTOR-lysoso...
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Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
The Power of Nup85: Controlling Molecular Traffic and Cellular Fate
Nup85 is a protein that plays a critical role in nucleocytoplasmic transport, facilitating the movement of macromolecules, including proteins and RNA, between the nucleus and the cytoplasm. Additiona...
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Two more reviews have just been published! #Clathrin is 2026 #Traffic superstar! onlinelibrary.wiley.com/doi/10.1111/... onlinelibrary.wiley.com/doi/10.1111/...
Integrating Lateral Super‐Resolution and Axial Progression Reveals Distinct Clathrin Pit Formation Pathways
Variable-angle total internal reflection fluorescence structured illumination microscopy (vaTIRF-SIM) links nanoscale lateral organization with axial progression during clathrin-mediated endocytosis....
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Traffic@traffic-journal.bsky.social · 2mo ago🎉 50 years of #Clathrin! The second article in Traffic's Special Issue is now online. #CellBiology #MembraneTrafficking #Endocytosis #TrafficJournal Edited by Emanuele Cocucci, Jeanne Stachowiak & Margaret Robinson. onlinelibrary.wiley.com/doi/10.1111/...
#Traffic is proud to inaugurate its #TrafficLights commentary section in a #JournalClub report format... it starts now with @JulieGavard onlinelibrary.wiley.com/doi/10.1111/...
Traffic Light Commentary—Src in the Upside Down: A Kinase Turned Inside Out
Just as Antelope Canyon transforms familiar rock into an unexpected hidden landscape, the topological inversion of Src reveals an unforeseen extracellular facet of kinase signaling in cancer. Antelop...
onlinelibrary.wiley.com
🎉 50 years of #Clathrin! The second article in Traffic's Special Issue is now online. #CellBiology #MembraneTrafficking #Endocytosis #TrafficJournal Edited by Emanuele Cocucci, Jeanne Stachowiak & Margaret Robinson. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
The Lack of a COPII Cargo Receptor Erv14 Impacts Physiological Functions of the Vacuole in Saccharomyces cerevisiae
Loss of the cargo receptor Erv14 in Saccharomyces cerevisiae results in sensitivity to calcium, zinc, neutral extracellular pH, and elevated temperature. Furthermore, cells deleted in the ERV14 exhib...
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Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
A Toolbox for Quantifying Nuclear and Nucleolar Protein Accumulation Using NLS and NoLS Fusion Reporters
Fluorescent proteins fused with nuclear (NLS) or nucleolar (NoLS) localization signals are commonly used for live assessment of protein accumulation in the nucleus and nucleolus. We present a standar...
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Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is...
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
KIF5B and Dynein‐Dependent Golgi Organization: Role in Adhesion‐Dependent Microtubule Acetylation
KIF5B and dynein regulate Golgi organization and localization- Role in regulating MT acetylation: In control (CNT) cells, active Arf1 facilitates the recruitment of KIF5B and dynein to the Golgi, mai....
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Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Protein Kinase D Regulates Kinesin‐Mediated VEGFR2 Trafficking and Influences Retinal Endothelial Permeability
Upon VEGF binding, VEGFR2 is autophosphorylated and recruits downstream signaling molecules, leading to protein kinase D (PKD)1 phosphorylation. We found that PKD1 phosphorylates KIF13B, a kinesin-3 ...
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Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Palmitoyl Acyltransferases Control the Membrane Localization of DNAJC5 to Regulate Unconventional Protein Secretion
Acylation of DNAJC5 by PAT facilitates its association with the Golgi apparatus, enhancing the secretion of abnormal cytosolic proteins via unconventional protein secretion.
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Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule-dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential phys...
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Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite
This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light ch...
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Just Published !! onlinelibrary.wiley.com/doi/10.1111/...
Copper Homeostasis at the Crossroads of Cellular Metabolism, Epigenetic Regulation and Protein Trafficking
Copper homeostasis is maintained in the cell by epigenetic regulation, and various metabolic processes. Regulated copper homeostasis balances normal protein trafficking, amino acid metabolism, etc., ...
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Beyond the Secretory Pathway: New Insights Into Protein Release
While proteins bearing N-terminal signal or leader sequences are secreted via the ER-Golgi-plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling sequen...
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Just Published ! Virion Associated Importin Subunit Beta‐1 Augments Nuclear Import of HIV‐1 Pre‐Integration Complex - Yandrapally - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
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Just Published! Spatiotemporal Analysis of Glucagon Secretory Granule Dynamics - Ghignoli - 2025 - Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/abs/10.1...
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Just published ! onlinelibrary.wiley.com/doi/10.1111/...
Strain‐Dependent Immune Signaling by Small Extracellular Vesicles Derived From Trypanosoma cruzi‐Infected Macrophages
Chagas disease, caused by Trypanosoma cruzi, remains a major treatment challenge due to variations in host immunity and parasite strains. We found that small extracellular vesicles (EVs) from infecte...
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Just published ! onlinelibrary.wiley.com/doi/10.1111/...
From Mechanisms to Therapy: Exploring the Role of Ferroptosis in Cervical Cancer Transformation and Treatment
This review mainly discusses the role of ferroptosis in cervical cancer from four aspects: underlying mechanisms, stage-specific sensitivity, ferroptosis-related targets and biomarkers, and clinical ...
onlinelibrary.wiley.com
Editor's selected articles of the last two years onlinelibrary.wiley.com/doi/toc/10.1...
Editors Choice Articles: Traffic
Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.
onlinelibrary.wiley.com
onlinelibrary.wiley.com/journal/1600... Traffic is a cell biology and biochemistry journal devoted to intracellular transport in health and disease, covering disciplines such as developmental biology, neuroscience, immunology, and infection in eukaryotes.
Traffic
Traffic is a cell biology and biochemistry journal devoted to intracellular transport, covering subcellular trafficking, membrane dynamics, organelle function & more.
onlinelibrary.wiley.com
Just Published ! onlinelibrary.wiley.com/doi/10.1111/...
FGF Signaling Promotes Lysosome Biogenesis in Chondrocytes via the Mannose Phosphate Receptor Pathway
FGF signaling regulates lysosomal homeostasis in RCS chondrocytes by inducing TFEB/TFE3 nuclear translocation and activation. This promotes the expression of lysosomal genes and mannose 6-phosphate r....
onlinelibrary.wiley.com
Just Published! onlinelibrary.wiley.com/doi/10.1111/...
CIN85 and CD2AP Are Novel Constituents of Dynamic Tubular Recycling Endosomes That Regulate Recycling Upon Recruitment by MICAL‐L1
In this study, we characterize tubular recycling endosomes and demonstrate that they are dynamic and undergo biogenesis upon CD98 internalization and fission over time. We identify CD2AP and CIN85 as...
onlinelibrary.wiley.com
Just published! onlinelibrary.wiley.com/doi/10.1111/...
Eukaryote‐Wide Distribution of a Family of Longin Domain‐Containing GAP Complexes for Small GTPases
The three longin domain-containing GAP complexes - CSW, folliculin, and GATOR1 - have a sporadic but pan-eukaryotic distribution and were likely already present in LECA in some form. Their catalytic ...
onlinelibrary.wiley.com
✍️ The Jackson/Verbavatz Lab contributed to the publication of a new article 📖 @traffic-journal.bsky.social 📃 Eukaryote-Wide Distribution of a Family of Longin Domain-Containing GAP Complexes for Small GTPases 🔗 onlinelibrary.wiley.com/doi/10.1111/...
Dacks Lab (Evolutionary Cell Biology)@dackslabecb.bsky.social · last yr.Wanna read about ARFGAPs, protists, Asgards, and the evolution of the endomembrane system? Have I got a paper for you! This was a pleasure to work on with two great collaborators, Cathy Jackson (@ijmonod.bsky.social) and Anna Novák Vanclová. onlinelibrary.wiley.com/doi/10.1111/...
@olzmannlab.bsky.social @tgalli.bsky.social @demangelab.bsky.social @agostinislab.bsky.social @abdourachidthiam.bsky.social @molinarilab-er.bsky.social @hennelab.bsky.social @jdejuan-sanz.bsky.social
Thierry Galli 🧫🧬🔬🎸🔊 🇪🇺🇫🇷@tgalli.bsky.social · last yr.ER_2025 #endoplasmicreticulum #ER #conference Paris October 8-10 2025 Register! itbcrde.inserm.fr/index.php?page…
Traffic has two calls for papers running: on #clathrin to to celebrate the 50th anniversary of its discovery and #UPS #unconventionalproteinsecretion onlinelibrary.wiley.com/page/journal...
onlinelibrary.wiley.com
Traffic has two calls for papers running: on #clathrin to to celebrate the 50th anniversary of its discovery and #UPS #unconventionalproteinsecretion onlinelibrary.wiley.com/page/journal...
onlinelibrary.wiley.com
Just published onlinelibrary.wiley.com/doi/10.1111/...
Salmonella Typhimurium Manipulates Syntaxin 7 to Navigate Endo‐Lysosomal Trafficking in Host Cells
Salmonella Typhimurium hijacks the host Qa-SNARE syntaxin 7 (STX7) to manipulate endo-lysosomal trafficking and sustain intracellular survival. STX7 displays cell–type–specific expression and localis...
onlinelibrary.wiley.com
