Brain mitochondria as key drivers of cognition and behaviour — a Review by Carmen Sandi, Mary Kay Lobo, Fiona Hollis, Yusuke Hirabayashi, Jaime de Juan-Sanz & Juan P. Bolaños #neuroscience #neuroskyence www.nature.com/articles/s41...

Brain mitochondria as key drivers of cognition and behaviour - Nature Reviews Neuroscience

Neuronal and glial mitochondria support neuronal circuit function and plasticity through the supply of energetic substrates and the regulation of cellular physiology. Sandi and colleagues describe how...

nature.com

The new Cajal Center is opening 8 CSIC permanent research positions (CT, IC & PF levels) via national competitive exams. We welcome candidates eager to shape an ambitious 🧠 research hub in Spain. 🔗 sede.csic.gob.es/tramites/con... 📣 #Neuroscience #CNC #CSIC #ScienceJobs 👇🏼

Centro de Neurociencias Cajal@cncajal-csic.bsky.social · 7mo ago

COME AND JOIN US‼️ ** TENURED SCIENTIFIC POSITIONS OPENED** • Brain recovery & neuropathology • Synaptic & computational mechanisms • AI & computational neuroscience • Bioinformatics / Data Science / AI in Biomedicine 📅 Apply by Jan 30, 2026 👉https://shorturl.at/vXCEW [BOE]

Exciting new tool for the study of mitochondrial metabolism! Thank you @jdejuan-sanz.bsky.social for sharing your plasmids.

Jaime de Juan-Sanz@jdejuan-sanz.bsky.social · 6mo ago

And forgot to say we made all tools available at @addgene.bsky.social at www.addgene.org/browse/artic... including our new low affinity MitoGCaMP for in vivo fly measurements of mitochondrial Ca2+!

📢Convocatoria 2026 de 10 plazas para la @academiajoven.bsky.social ➡️Plazo de inscripción abierto hasta el 28 de febrero (improrrogable) Más información en: academiajoven.es 👉convocatoria2026@academiajoven.es

And forgot to say we made all tools available at @addgene.bsky.social at www.addgene.org/browse/artic... including our new low affinity MitoGCaMP for in vivo fly measurements of mitochondrial Ca2+!

Jaime de Juan-Sanz@jdejuan-sanz.bsky.social · 6mo ago

Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!

Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!

Nature Metabolism@natmetabolism.nature.com · 6mo ago

Y tú ¿Qué quieres ser de mayor? La @academiajoven.bsky.social lucha para que ninguna niña deje de soñar, imaginar, de innovar, Y ESTIMULA la curiosidad CIENTÍFICA y el interés por aprender de las niñas y las jóvenes. ¡Que todas las MUJERES puedan SEGUIR SUS VOCACIONES CIENTÍFICAS!

And fun to ready the commentary by the Misgeld lab - thanks for highlighting our work! www.nature.com/articles/s42...

Fuelling the brain with calcium - Nature Metabolism

Calcium entry into mitochondria couples neuronal activity to energy supply, but whether boosting this drive can enhance brain function has remained unclear. Vishwanath et al. now demonstrate that tuni...

nature.com

Jaime de Juan-Sanz@jdejuan-sanz.bsky.social · 6mo ago

Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!

Can we make brains “smarter”? By boosting mitochondrial metabolism in neurons of memory circuits, we improved memory in flies and mice. Thrilled to see this work out - congrats to @amrapalianjali.bsky.social for spectacular work, and to all lab members for invaluable contributions!

Nature Metabolism@natmetabolism.nature.com · 6mo ago

Beyond excited to be awarded an ERC consolidator! Exciting times ahead for the lab. Very thankful to lab members for their work every day that made this possible!! Time to celebrate!

European Research Council (ERC)@erc.europa.eu · 8mo ago

The results of the ERC Consolidator Grant call have been announced! 📣 349 researchers have been selected for funding. Congratulations to all! #ERCCogG! 👉 buff.ly/uu62uFV #FrontierResearch #EUfunded #HorizonEurope @scienceinnovation.ec.europa.eu

I am super thrilled to announce that I have been awarded an @erc.europa.eu Consolidator Grant to build novel interventions for #OCD. The plan is to exploit recent insights from computational neuroscience and closely work together with people with lived experience of OCD to create novel treatments.

a little girl is dancing in front of a group of people sitting on chairs .

ALT: a little girl is dancing in front of a group of people sitting on chairs .

media.tenor.com

Beyond excited to be awarded an ERC consolidator! Exciting times ahead for the lab. Very thankful to lab members for their work every day that made this possible!! Time to celebrate!

European Research Council (ERC)@erc.europa.eu · 8mo ago

The results of the ERC Consolidator Grant call have been announced! 📣 349 researchers have been selected for funding. Congratulations to all! #ERCCogG! 👉 buff.ly/uu62uFV #FrontierResearch #EUfunded #HorizonEurope @scienceinnovation.ec.europa.eu

Outstanding PhD fellowship call OPEN for excellent students. lacaixafoundation.org/en/doctoral-... This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels). If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!

Doctoral INPhINIT fellowships - Incoming Call 2026

We grant 30 fellowships for researchers of any nationality who wish to pursue a doctorate in a STEM discipline at research centres of excellence in Spain or Portugal.

google.com

Call for junior or mid-career group leaders in neuroscience! Apply by 30 Jan to join the FENS-Kavli Network. We are looking for excellent and engaged future scholars who are committed to exchanging scientific ideas & improve neuroscience in Europe. fenskavlinetwork.org/who-we-are/a...

⚠️ Half of commercial antibodies miss their target! So how do you pick the right one for your experiment? Here’s the solution 👉 Antibody characterization data (all tested in KO cells) are now available at: 🔗 onlygoodantibodies.co.uk Tested by @ycharos.bsky.social & @oga-community.bsky.social

What do we know about the causes of #autism? @kingscollegelondon.bsky.social Professor Laura Andreae speaks with BBC Radio 4's Inside Science about the genetic factors behind autism, particularly around twin studies. 🔊 Listen now: www.bbc.co.uk/sounds/play/...

BBC Inside Science - The science behind autism - BBC Sounds

What do we know about the causes of autism?

bbc.co.uk

Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social labs www.nature.com/articles/s41...

Temporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature Communications

This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...

nature.com

Excited that the paper presenting our mouse brain in vivo CRISPR screening platform is out today in @natneuro.nature.com! Great team effort, led by Biswa Ramani and @ivlrose.bsky.social in the Kampmann lab. www.nature.com/articles/s41...

CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes - Nature Neuroscience

The authors developed an adeno-associated virus-based high-throughput in vivo CRISPR screening platform for endogenous mouse brain cell types. Using this platform, they define genes and pathways essen...

nature.com

ER_2025 #endoplasmicreticulum #ER #conference Paris October 8-10 2025 Register! itbcrde.inserm.fr/index.php?page…

Another example! 🚲🚲🚲

Jaime de Juan-Sanz@jdejuan-sanz.bsky.social · last yr.

Always faster to 🚲 in Paris!

Always faster to 🚲 in Paris!

Nicer pics from the @academiesciences.bsky.social ceremony - a great occasion to celebrate our recent work together with @stefvass.bsky.social @florianwerner.bsky.social and @moparthisk.bsky.social! Photos © Académie des sciences – Mathieu Baumer.

Christophe 🔬 Leterrier@christlet.bsky.social · last yr.

Honored to be on stage this morning @academiesciences.bsky.social for the work done with @florianwerner.bsky.social and @moparthisk.bsky.social. Also celebrating almost ten years of collaboration and friendship with @stefvass.bsky.social, merging microscopies to discover new biology 🤝

Had a blast in the SynAnb/generate symposium in Tutzing! Lots to learn about the relationship between the immune system and the brain (and how things can go south). Thanks for the invite!

20 days waiting for an editorial decision on whether our paper will be sent for review at @elife.bsky.social — did others have a similar experience? I wonder if these long timelines will make it somewhat hard to support the new model

Real fun hosting @chaichinta.bsky.social to discuss how to merge theory and experiments in ATP diffusion in axons. Thanks to @kavlifoundation.org for funding these exchanges!

"Tanner, a chemist at the Univ. of Mississippi working to develop a novel approach for treating glioblastoma, was notified in April that the grant was terminated. “I would like to cure brain cancer,” Dr. Tanner said. “I think that's not particularly controversial.” www.nytimes.com/interactive/...

The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant

Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

nytimes.com

A really important skill for trainees to learn is to be a “closer” of a project-that is to take it over the finish line for publication. This means doing the experiments, getting the figures/text ready for submission and being prepared to do review corrections 😀

This is a summary of our recent @jcellsci.bsky.social paper. If you've ever wondered why ATG9A has many and varied roles, we think it's because it is trafficked by a subset of a large, diverse family of vesicles - intracellular nanovesicles. doi.org/10.1242/jcs....

ATG9A vesicles are a subtype of intracellular nanovesicle

Highlighted Article: Presentation of the first intracellular nanovesicle (INV) proteome, showing that a subset of INVs are ATG9A vesicles. This places ATG9A vesicles in a broader superfamily of traffi...

doi.org