Traver Hart
@traver.bsky.social
Assoc Prof, MD Anderson. Functional genomics, CRISPR/Cas12a genetic interactions & synthetic lethality, history, politics, snark.
I will not abide this Perl erasure!
Python got bioinformatics started. Rust will scale it. 🦀 Today we released rustyomestats, our first Rust crate for genome assembly statistics. Fast. Memory safe. Built for massive genomic datasets. Crates: lnkd.in/dP88c83F GitHub: lnkd.in/dDw2KNuX Rust is the way. #RustLang #Bioinformatics
US Secretary of the Department Formerly Known as Defense says all his servicemembers have bodily autonomy. 🍿
I have been compelled to withdraw a manuscript from Science Advances due to complete lack of editorial support. We have been waiting almost two full months to learn whether they even consider the work worthy of peer review. Am I an outlier here, or have others had similar experiences?
🧬 We're hiring scientists! I'm building a new team at the Generative Biology Institute, Ellison Institute of Technology Oxford, next to colleagues in AI, Robotics, and Plant Biology.
Parts team
partslab.bio
We are also considering postdoc candidates with deep perspectives on transcription factor / chromatin biology, and would like to tackle such topics using high-throughput synthetic biology approaches.
My lab at UCSF is recruiting postdoc candidates interested in CRISPR synthetic biology and functional genomics approaches to study and engineer tissue injury responses! hsiunglab.org
Imagine thinking you might have an air defense system, then having these lumbering senior citizens plodding uncontested through your airspace.
🇺🇸✈️🇮🇷 CENTCOM: During the first 100 hours of Operation Epic Fury, B-52s struck Iranian ballistic missile and command and control posts.
first order effect: US air defense assets, especially high end SAMs, being used to defend middle east assets second order: less avail for Ukraine. more effective Russian ballistic missile strikes. cruise missiles, drones not so much. third order: China laughing as US stockpiles depleted.
Can confirm: this tool is very impressive. I'm fully bought into our AI-enhanced future. We will look back on the previous epoch as if we were living in black and white. Unfortunately the planet will be metaphorically black and white, with nothing but sun-blasted stone and shrunken seas. Oh well.
I just tested q.e.d for a grant proposal and am blown away. The suggested changes are on the point and will surely help my proposal. This is amazing! @odedrechavi.bsky.social Can't wait to submit my next paper before preprint to q.e.d! 🧪
Rosalind's companion piece to our genetic interactions manuscript. GRAPE, to analyze synthetic lethality screens, and Synulator, to generate simulated synthetic lethal gold standards because none exist today. www.biorxiv.org/content/10.6...
biorxiv.org
Rosalind's companion piece to our genetic interactions manuscript. GRAPE, to analyze synthetic lethality screens, and Synulator, to generate simulated synthetic lethal gold standards because none exist today. www.biorxiv.org/content/10.6...
biorxiv.org
Playing Baldur's Gate 3 just so my computer will heat up my office.
Merry Christmas, genetic interaction nerds: www.biorxiv.org/content/10.6...
Functional modules predict cancer-relevant genetic interactions in mammalian cells
Genetic interactions can reveal gene function and identify cancer-relevant synthetic lethals, but systematic mapping in human cells is constrained by inefficient reagents, vast combinatorial search sp...
biorxiv.org
Delighted to host Traver Hart (MD Anderson Cancer Center), who delivered an engaging seminar on synthetic lethality at #HumanTechnopole. He showed how bridging #CRISPR and predictive modeling can advance design and interpretation of genetic interaction screens and inform new therapeutic strategies.
Adaptive behavior of predatory publisher "editors" - I was just invited to review one or more of a list of five articles, each submitted to different journals. I haven't seen that before.
I can withdraw from social media now. I have learned everything worth learning.
Ok its ‘feed it off an aux, speak, grunt no strength, the ladder start to clatter with fear fight down height, wire in a fire representing seven games, a government for hire and a combat site’.
Ruin a movie by making it about Gary The Cook, The Thief, His Wife, and Gary
Ruin a movie by making it about Gary Dances With Gary