Turvey Lab
@turveylab.bsky.social
Dr. Stuart Turvey and the Turvey lab are committed to improving child health through research. Our research transforms lives. There is urgency to what we do! We are based at UBC and BC Children's Hospital, Vancouver, Canada. 🇨🇦 https://turveylab.com/
Autosomal recessive OSMRβ deficiency: connecting OSM and/or IL-31 with #atopy. Anne Puel, @casanovalab.bsky.social, and Vivien Béziat discuss two studies by Andersen et al. (rupress.org/jhi/article/...), and @turveylab.bsky.social: (rupress.org/jhi/article/...): rupress.org/jhi/article/...
(2/2) This News & Views highlights two studies by Andersen et al. (rupress.org/jhi/article/...), and by Samra and Sharma et al. @turveylab.bsky.social: (rupress.org/jhi/article/...)
Oncostatin M receptor deficiency as a novel candidate genetic cause of autosomal recessive hyper-IgE syndrome
Here, Andersen and colleagues describe a patient with asthma, pulmonary aspergillosis, and elevated IgE homozygous for a deleterious variant in the oncosta
rupress.org
Puel, @casanovalab.bsky.social & Béziat discuss two studies reporting autosomal recessive OSMRβ deficiency as a new inborn error of immunity marked by severe #atopy, hyper-IgE, & #eosinophilia, thereby refining the genetic dissection of #STAT3-dependent hyper-IgE syndrome rupress.org/jhi/article/...
(2/2) This News & Views highlights two @jhumimmunity.org studies by Andersen et al. (rupress.org/jhi/article/...), and by Samra and Sharma et al. @turveylab.bsky.social: (rupress.org/jhi/article/...)
Oncostatin M receptor deficiency as a novel candidate genetic cause of autosomal recessive hyper-IgE syndrome
Here, Andersen and colleagues describe a patient with asthma, pulmonary aspergillosis, and elevated IgE homozygous for a deleterious variant in the oncosta
rupress.org
Thank you, Anne, Jean-Laurent, and Vivien, for this wonderful News & Views, and congratulations to Trine Mogensen and colleagues on their complementary study. It's exciting to see independent discoveries establish OSMRβ deficiency as a new inborn error of immunity. @casanovalab.bsky.social
Rockefeller University Press@rupress.org · 2w agoPuel, @casanovalab.bsky.social & Béziat discuss two studies reporting autosomal recessive OSMRβ deficiency as a new inborn error of immunity marked by severe #atopy, hyper-IgE, & #eosinophilia, thereby refining the genetic dissection of #STAT3-dependent hyper-IgE syndrome rupress.org/jhi/article/...
It was a pleasure to help @anne_puel and @BeziatV write this News & Views about spectacular discoveries by @TurveyLab and Trine Mogensen ! Autosomal recessive OSMRβ deficiency: Connecting OSM and/or IL-31 with atopy rupress.org/jhi/article/...
Autosomal recessive OSMRβ deficiency: Connecting OSM and/or IL-31 with atopy
In this News & Views, we discuss two studies reporting autosomal recessive OSMRβ deficiency as a new inborn error of immunity marked by severe atopy, h
rupress.org
Meet Meghan, a leading CHILD researcher! 👋 💡Fun Fact: She is an outdoor adventure & cycling enthusiast! 🚴♂️ 🔬Research focus: How breastfeeding shapes infant development & long-term health.🤱🏽 ❤️Favorite part of CHILD: Endless opportunities to explore new research questions. www.childcohort.ca/meghan-a/
As head of the @ubcmedicine.bsky.social Dept of Medical Genetics, I am delighted to share that in collaboration with @bcchresearch.bsky.social we are recruiting a tenure track Assistant Professor clinician scientist: ubc.wd10.myworkdayjobs.com/ubcfacultyjo... There's 0.4FTE clinical attached!
Assistant Professor (Tenure Track)
Academic Job Category Faculty Bargaining Job Title Assistant Professor (Tenure Track) Department Department of Medical Genetics | Faculty of Medicine | Provost and VP Academic (Jehannine Austin) Posti...
ubc.wd10.myworkdayjobs.com
Online now: Breastfeeding may lessen socioeconomic disparities in child health through differences in the infant gut microbiome
Breastfeeding may lessen socioeconomic disparities in child health through differences in the infant gut microbiome
Darlene Dai, Charisse Petersen, Stuart Turvey, and colleagues report that breastfeeding may mitigate the adverse effects of socioeconomic disadvantage on early risk factors for non-communicable diseases. The authors link this effect to differences in infant gut microbiota, including enrichment of Bifidobacterium infantis, highlighting potentially modifiable pathways underlying intergenerational health inequities.
dlvr.it
Our latest article features Dr. Stuart Turvey and Dr. Elie Haddad on how collaboration, clinical trials, precision health, and gene editing are helping transform pediatric rare disease research and access to treatment. www.rarekidscan.com/news/rewriti...
Rewriting Rare Disease Care: How Collaboration and Clinical Trials Are Transforming Pediatric Research and Access to Treatment — RareKids-CAN
Canada is entering a new era in pediatric rare disease research, driven by advances in precision medicine and novel, innovative clinical trial approaches, including gene editing and gene therapies.
rarekidscan.com
Find that CHILD publication! 📰 You can now search our online database of CHILD publications to a high degree of detail: we have added keywords 🔑 & the search now scans each publication’s abstract. Explore our 250+ peer-reviewed publications here: childcohort.ca/results-to-d...
Thrilled to see our paper featured on the July cover of the Journal of Human Immunity. We describe the first global cohort of patients with biallelic OSMR deficiency, establishing a new primary atopic disorder. A huge thank you to the patients, families, and international collaborators.
Journal of Human Immunity@jhumimmunity.org · 2mo agoOur July issue is here! rupress.org/jhi/issue/2/4 This cover highlights the first human biallelic OSMR deficiency. @turveylab.bsky.social et al. show that OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. doi.org/10.70962/jhi...
Thrilled to see our paper featured on the July cover of the Journal of Human Immunity. We describe the first global cohort of patients with biallelic OSMR deficiency, establishing a new primary atopic disorder. A huge thank you to the patients, families, and international collaborators.
Rockefeller University Press@rupress.org · 2mo ago@jhumimmunity.org's July cover (rupress.org/jhi/issue/2/4) highlights the first human biallelic OSMR deficiency. @turveylab.bsky.social et al. show that OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. doi.org/10.70962/jhi...
Our July issue is here! rupress.org/jhi/issue/2/4 This cover highlights the first human biallelic OSMR deficiency. @turveylab.bsky.social et al. show that OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. doi.org/10.70962/jhi...
@jhumimmunity.org's July cover (rupress.org/jhi/issue/2/4) highlights the first human biallelic OSMR deficiency. @turveylab.bsky.social et al. show that OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. doi.org/10.70962/jhi...
CHILD research out of @turveylab.bsky.social & published in Nature Communications reveals that certain gut fungi 🍄 play a key role in the development of the immune system & in the development in kids of allergic asthma 😮💨 & some allergies. More: childcohort.ca/gut-fungi-ke...
Really nice balanced summary of our recent @natcomms.nature.com paper! studyfinds.com/gut-fungus-d...
Studies Find Gut Fungus Possibly Driving Childhood Allergies: Antibiotics May Be Making It Worse
Gut fungi have been overlooked in allergy research for years. Two new studies suggest that may have been a costly mistake.
studyfinds.com
Gut fungi may hold the key to treating Asthma worldwide | EurekAlert! www.eurekalert.org/news-release...
Gut fungi may hold the key to treating Asthma worldwide
Two new studies jointly published in Nature: The Clinical Microbiome reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric aller...
eurekalert.org
The microbiome story isn’t just about bacteria. Our new work shows the infant mycobiome—gut fungi like Malassezia and Saccharomyces—plays an important role in immune development and childhood allergy. An exciting new frontier for pediatric precision health. www.news-medical.net/news/2026062...
Gut fungi play key role in pediatric allergic diseases development
Two new studies jointly published in Nature: The Clinical Microbiome reveal that certain species of fungi in the gut play a key role in the development of immune dysregulation and some pediatric aller...
news-medical.net
Two back-to-back @natcomms.nature.com papers highlight the infant mycobiome as a key player in immune development: one links fungal maturation to allergy risk, the other shows how antibiotic-driven Malassezia expansion promotes airway inflammation. A great day for 🇨🇦 microbiome science. rdcu.be/fp1ly
rdcu.be
Science matters most when it reaches the communities it aims to serve. Delighted to see first author Dr. Darlene Dai discuss our recent @cp-cellrepmed.bsky.social study on OMNI News in Cantonese and Mandarin. 📄 www.cell.com/cell-reports... youtu.be/GtsQ4c85fBU?...
研究：母乳餵哺或助減兒童健康差距 | OMNI News Cantonese
YouTube video by OMNI Television
youtu.be
A major milestone for @jhumimmunity.org with PubMed and PubMed Central indexing. We are building a home for outstanding human immunology—from fundamental discovery to clinical translation with a focus on monogenic disorders—and look forward to the next generation of exciting submissions.
Journal of Human Immunity@jhumimmunity.org · 3mo ago🌐 Journal of Human Immunity (JHI) is now officially indexed in #PubMed Central and PubMed. This includes all future papers and the complete back catalog dating back to our first issue. Read the full announcement and explore the journal here: rupress.org/jhi/pages/pm...
I’m delighted to see @jhumimmunity.org achieve PubMed and PubMed Central indexing. This is an important milestone for the journal and for the field. I look forward to seeing more outstanding studies in human immunology and immune-mediated disease submitted to JHI.
Rockefeller University Press@rupress.org · 3mo ago🌐 Journal of Human Immunity (JHI) @jhumimmunity.org is now officially indexed in #PubMed Central and PubMed. This includes all future papers and the complete back catalog dating back to our first issue. Read the full announcement and explore the journal here: rupress.org/jhi/pages/pm...
Really happy with this new paper just published in @jhumimmunity.org
Journal of Human Immunity@jhumimmunity.org · 3mo agoHuman germline biallelic loss-of-function OSMR variants cause severe allergic disease. New study from Simran Samra, Mehul Sharma, Stuart E. Turvey @turveylab.bsky.social and colleagues: rupress.org/jhi/article/... #Immunology #Genetics #Atopy #IEIs #InbornErrorsOfImmunity
CIHR on the move for real Impact! Joint meeting of the advisory boards for the Institutes of Indigenous Peoples’ Health and Infection & Immunity. Warmly welcomed and hosted at the Kwanlin Dun Cultural Centre. @ckaushic.bsky.social @tammyjcliffordphd.bsky.social #yukon #whitehorse
Published! Biallelic OSMR deficiency is a new Primary Atopic Disorder. A rare disease that provides new insights into the mechanisms of human allergic disease. A wonderful international team effort.
Rockefeller University Press@rupress.org · 3mo agoNew human primary atopic disorder defined: In @jhumimmunity.org, Samra and Sharma et al. show OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. rupress.org/jhi/article/... #Immunology #Genetics #Atopy #IEIs @turveylab.bsky.social
OSMR study published! By identifying biallelic OSMR deficiency as a novel Primary Atopic Disorder, we uncover a previously unrecognized mechanism driving severe allergic disease and provide new insights into the biology of human atopy. Congratulations to an outstanding team of collaborators.
Journal of Human Immunity@jhumimmunity.org · 3mo agoNew human primary atopic disorder defined: Samra and Sharma et al. show OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. rupress.org/jhi/article/... #Immunology #Genetics #Atopy #IEIs @turveylab.bsky.social
Check our new Editorial comment: Italian pediatric experts consensus statement on diagnosis and management of primary atopic disorders' - Vaseghi‐Shanjani - 2026 - Pediatric Allergy and Immunology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
Editorial comment: Italian pediatric experts consensus statement on diagnosis and management of primary atopic disorders'
“Primary Atopic Disorders (PAD) are a recently recognized group of inborn errors of immunity characterized by severe allergic manifestations. Due to their overlapping features with common atopic dise...
onlinelibrary.wiley.com
BCCHR's Dr. Charisse Petersen from the @turveylab.bsky.social was interviewed by @ctvnewsvancouver.bsky.social on their latest study on how breastfeeding may lessen socioeconomic disparities in child health. www.ctvnews.ca/vancouver/vi...
Study finds breastfeeding benefits last into childhood
BC Children’s Hospital Research Institute’s Dr. Charisse Petersen discusses how breastfeeding may help protect infants with Your Morning Vancouver.
ctvnews.ca
