BC Children's Hospital Research Institute

@bcchresearch.bsky.social

BC Children's Hospital Research Institute conducts discovery, translational and clinical #research to benefit the #health of children and their families.

Published! Biallelic OSMR deficiency is a new Primary Atopic Disorder. A rare disease that provides new insights into the mechanisms of human allergic disease. A wonderful international team effort.

Rockefeller University Press@rupress.org · 4mo ago

New human primary atopic disorder defined: In @jhumimmunity.org, Samra and Sharma et al. show OSMR deficiency disrupts OSM-STAT signaling, driving severe early-onset #eczema, #eosinophilia, and elevated IgE. rupress.org/jhi/article/... #Immunology #Genetics #Atopy #IEIs @turveylab.bsky.social

Kicking off CSI day 2 strong with the vaccine symposium. Great opening session by Dr. Charu Kaushic and keynote speaker Dr. Natasha Crowcroft. We also heard amazing talks from Dr. Devon Greyson, Dr. Matthew Miller, Dr. Manish Sadarangani, and Dr. Rae Yeung for Session 2.

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New research from BCCHR, uses longitudinal data from the CHILD Cohort Study, to show that breastfeeding acts as a shield, protecting the infant microbiota from many different exposures well into early childhood. The impact is especially clear among children from lower socioeconomic status.

Cell Reports Medicine@cp-cellrepmed.bsky.social · 6mo ago

Online now: Breastfeeding may lessen socioeconomic disparities in child health through differences in the infant gut microbiome

Construction is well underway on the new centre for health complexity at BC Children's Hospital, a first-of-its-kind facility in Canada. 🏗️ This new centre will help connect families across BC with the services, & care they need. The project is on budget & on track to open in early 2028.

On #CMAJPodcasts, Drs. Megan Cooney and Matthew Carwana discuss how the TEN‑4‑FACESp rule helps identify bruising patterns concerning for physical abuse, and what pandemic-era hospitalization trends reveal about the severity of maltreatment in infants and toddlers. ➡️ www.cmaj.ca/transcript-251219