@ihgatucsf.bsky.social and @ucsfstemcell.bsky.social are excited to inform you about the annual Genotech Symposium, taking place on 9/23. The goal is to foster collaboration and cross-fertilization between industry and academia in genetics and genomics. Hope to see you there! genotech.ucsf.edu

Exercise protects the brain, and now UCSF researchers may have discovered how: An exercise-induced protein appears to strengthen the blood-brain barrier, slowing decline. “We’re uncovering biology that Alzheimer’s research has largely overlooked,” Saul Villeda says. https://ucsfh.org/4aAJ9OQ

Scientists Find a Mechanism for How Exercise Protects the Brain

A UCSF team finds a liver protein, released with exercise, that improves memory in aging and Alzheimer’s disease by repairing the brain’s blood vessels. It's the missing link between exercise and brai...

ucsf.edu

Congratulations, @konjikusicmia.bsky.social. It makes my heart well up to have this cohort named in memory of Zara, an extraordinary scientist.

Leading Edge Fellows Program@leadingedgeprogram.bsky.social · 2mo ago

We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/

Congratulations, Corey Harwell, PhD, on being named a 2026 McKnight Neurobiology of Brain Disorders Award recipient. His work investigates how brain circuits are built and how disruptions in these pathways may contribute to neurological and developmental disorders: stemcell.ucsf.edu/news/corey-h...

Excited to have the ISSCR 2027 Annual Meeting here in San Francisco! 🧬

ISSCR@isscr.org · 3mo ago

In 2027, ISSCR returns to San Francisco to recognize 25 years of discovery, collaboration, and progress in stem cell science; to gather the people, ideas, and work that will shape the next quarter century. Join us in San Francisco, USA, 15–18 June 2027. https://ow.ly/hqR650Z1FGP

Research led by Tomasz Nowakowski, PhD @ucsanfrancisco.bsky.social @ucsfstemcell.bsky.social in @nature.com | New map of fetal brain cell development may change our understanding of mental illness and cancer www.earth.com/news/new-map... #UCSFProud

New map of fetal brain cell development may change our understanding of mental illness and cancer

A chronological map of the fetal brain reveals when key cells emerge and provides clues about autism and cancer.

earth.com

Peng He & colleagues published “Toward informed batch correction for single-cell transcriptome integration” in Nature Computational Science. They review current data cleaning methods & envision interpretable frameworks that model technical + biological variation in single-cell data: rdcu.be/e4cSp

Toward informed batch correction for single-cell transcriptome integration

Nature Computational Science - Batch effects pose substantial challenges for obtaining meaningful biological insights from large-scale yet heterogeneous single-cell RNA-sequencing datasets. Here...

rdcu.be

15 years ago today, @ucsanfrancisco.bsky.social celebrated the opening of the Ray & Dagmar Dolby Regeneration Medicine Building on our Parnassus campus. Take a look back at scenes from opening day and move-in, and see what our researchers are working on today: stemcell.ucsf.edu/2024-2025-uc...

The UCSF Broad Stem Cell Center and Department of Surgery invite applications for a new faculty position focused on the development of delivery tools for gene editing to enable cutting-edge gene therapies. Please share and apply 🔗 aprecruit.ucsf.edu/JPF05914

Nature research paper: Dissecting gene regulatory networks governing human cortical cell fate go.nature.com/4qBG5rp

Dissecting gene regulatory networks governing human cortical cell fate - Nature

Systematic screening of transcription factors reveals conserved mechanisms governing cortical radial glia lineage progression across primates and provides a framework for functional dissection of gene regulatory networks in human cortical neurogenesis.

go.nature.com

Researchers in Diana Laird's lab discovered the decline in female fertility w/age isn’t driven solely by eggs; other cells in the ovary, including glia and fibroblasts, influence ovarian health & aging—part of UC’s top discoveries of 2025. #UCSFProud www.universityofcalifornia.edu/news/10-awes...

10 awesome discoveries from UC research in 2025

A year of new treatments, new technologies, new ways to stay safe during disasters and new insights on the mysteries of the galaxy, our planet and our past.

universityofcalifornia.edu

Kyle Cromer's team published collaborative work with Stanford in @bloodadvances.bsky.social using CRISPR tools to create a mouse model of a rare juvenile leukemia. Congrats to Roshani Sinha, Devesh Sharma, & Benjamin Lesch for co-authoring this publication. More: ashpublications.org/bloodadvance...

Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...

Conservation and alteration of mammalian striatal interneurons - Nature

An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...

nature.com

Happening TODAY! Tune in at noon for #UCSFSOTU 2025 with Chancellor Sam Hawgood. Hear about UCSF’s accomplishments from the past year and how our institution is innovating to adapt for the future. tiny.ucsf.edu/HuBTYF

State of the University Address

Live viewing page of the annual UCSF Chancellor's State of the University Address.

tiny.ucsf.edu

New issue of Nature - with NINE studies on #brain #development from the BRAIN Initiative Cell Atlas Network (BICAN) 🧠🧪🔬 An amazing set of resources for all scientists working on the brain! 🧠 Immersive feature: www.nature.com/immersive/d4... 🧠 Perspective: www.nature.com/articles/s41...

The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor. The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2. www.leadingedgesymposium.org/apply/

We love this!! ❤️ #UCSFProud

Dr. Elizabeth Crouch@elizabethcrouch.bsky.social · 10mo ago

Grateful and inspired by #CIRM funding and programing for the #ReMIND initiative. The future will be better for neuropsychiatric disease 🧠 🩺 🩸 @ucsfstemcell.bsky.social @bhadurilab.bsky.social @brainevodevo.bsky.social

Happy World CRISPR Day! The CRISPR revolution began with genome editing, but the platform has evolved into a versatile molecular toolkit with wide-ranging applications. The current issue of TiG includes a Review of these applications. Check it out! www.cell.com/trends/genet...

Expanding horizons of CRISPR applications beyond genome editing

Clustered regularly interspaced short palindromic repeats (CRISPR) technologies have rapidly evolved beyond genome editing, transforming fields such as molecular diagnostics, biosensing, transcription...

cell.com

Join us today, 10/16, for Getting to Patients! Dr. Claire Clelland will share “Developing CRISPR gene therapy for C9orf72 FTD/ALS: the path ahead to clinic” with Special Guests and perspectives from a family with the C9orf72 gene tiny.ucsf.edu/14kshU @ucsfsurgery.bsky.social

Congrats to Kyle Cromer, PhD, on receiving an NIH Director’s New Innovator Award! Dr. Cromer is working on better treatments for sickle cell disease by trying to help the bone marrow produce more healthy red blood cells. 🧬 #UCSFProud www.ucsf.edu/news/2025/10...

A new imaging technique and single-cell sequencing reveal a deeper understanding of ovarian aging. @ucsanfrancisco.bsky.social & @czbiohub.bsky.social study could be key to strategies for extended fertility and healthier aging. www.ucsf.edu/news/2025/10...

Why Does Female Fertility Decline So Fast? The Key Is the Ovary

New research shows that the surrounding cells and tissues of the ovary play a crucial role in how eggs mature and how quickly fertility wanes.

ucsf.edu

For #StemCellAwarenessDay, a look at a human neuron grown from stem cells, captured by Dr. Yonatan Perez, a Kriegstein Lab postdoc alum. This work could inform therapies for neurological disorders and brain regeneration.

Congratulations to our Broad Center members (Bruce Conklin, Tippi MacKenzie, Jingjing Li, Benoit Bruneau, and Holger Willenbring) and colleagues on their newly awarded CIRM Discovery (DISC0) grants!

California Institute for Regenerative Medicine (CIRM)@cirmnews.bsky.social · 10mo ago

“Discovery research is critical for uncovering novel disease targets and biomarkers that we can translate into therapies for clinical use,” said Kelly Shepard, PhD, Director of Discovery & Education programs at CIRM. Read the full announcement: https://bit.ly/4gDLREC

From cloudy mornings to golden sunsets—the UCSF Broad Stem Cell Center always has a view worth sharing. 🌿☀️ Thanks to Lael and Cassie from the IRM Admin Team for these shots! #UCSF #Dolby #KarlTheFog #OfficeViews #CampusViews #GoldenHour

Congratulations, Tomasz Nowakowski, PhD! 🧬🧠✨ #UCSFProud

UCSF Neurosurgery@neurosurgucsf.bsky.social · 11mo ago

Congratulations to Tomasz Nowakowski, PhD, on being named a finalist for the prestigious Blavatnik National Award for Young Scientists! 🎉 He was selected for his groundbreaking research shaping the future of neuroscience and medicine. stemcell.ucsf.edu/news/tomasz-... @ucsfstemcell.bsky.social 🧪 🧠📈

The University of California provides transformative educational opportunities, life-saving health care and research that moves our state forward and powers our economy. Stand with UC for the future of California: bit.ly/46LvcMo youtu.be/OpvhTJtxF5o?...

The University of California: Boldly Californian

YouTube video by University of California

youtu.be

Congrats to Lilian Gomes de Oliveira, PhD, who joins the 2025 class of Pew scholars and fellows! As a Pew Latin American Fellow, Lilian will explore how the Zika virus disrupts cerebral cortex development during the second trimester of pregnancy. Learn More: www.pew.org/en/about/new...

New from the Cromer Lab detailing methods for achieving high-efficiency CRISPR-based genome editing in primary hematopoietic stem and progenitor cells (HSPCs). Discover more @cp-starprotocols.bsky.social | star-protocols.cell.com/protocols/4394

So proud of Kaylee who won a #GordonConference Travel Award! 🥇 🤩 Congrats to @brisapalikuqilab.bsky.social for a fantastic #GRS and Profs Karina Yaniv and Anne Eichmann for an outstanding #Angiogenesis conference @ucsfchildrens.bsky.social @ucsfstemcell.bsky.social

Congratulations, Jaela Caston and @elizabethcrouch.bsky.social!! We’re #UCSFProud to celebrate you as 2025 Gilliam Fellow & Advisor 🎉 @ucsanfrancisco.bsky.social www.hhmi.org/programs/gil...

HHMI@hhmi-science.bsky.social · 12mo ago

Congratulations 2025 Gilliam Fellows and Advisors! 🎉 The Gilliam Fellows Program launches promising PhD students into impactful scientific research careers while fostering inclusive training environments. Through this program, HHMI supports both graduate students and their faculty thesis advisors.