On my way to @faseborg.bsky.social Cilia and Centrosomes conference, the Ciliopathy Summit and the Bardet-Biedl syndrome family day in balmy DC. I hope I see you there!

📣 Abstract submission and early registration are now OPEN for the 7th European Cilia Conference—an official EMBO workshop! 📅 8–12 March 2027 📍 Stresa, Italy Submit and register: meetings.embo.org/event/27-cilia www.eurocilia.eu #EMBOCilia #Cilia2027

Learn about cilia (dis)assembly, how cargo selection is regulated and how functions vary across tissues at the EMBO Workshop "Cilia" in Stresa, Italy, 9–12 March 2027. Early bird registration by 30 Sep Abstract submission by 30 Oct https://meetings.embo.org/event/27-cilia #EMBOcilia #EMBOevents 🧪

Looking forward to our @ihgatucsf.bsky.social yearly Genotech Symposium in collaboration this year with @ucsfstemcell.bsky.social on September 23rd. We have a great line up of speakers, networking options, amazing sponsors and registration is free of charge. Hope to see you there! genotech.ucsf.edu

For neuroscience PhDs with a strong interest in teaching and mentoring: MIT is hiring a scientific program manager to support activities around a new NIH neuroscience PhD training grant. Salary range $91k - $129k #NeuroJobs careers.peopleclick.com/careerscp/cl...

Scientific Program Manager

MIT - Scientific Program Manager - Cambridge MA 02139

careers.peopleclick.com

'(...) if trainees are spending years as a graduate student at quite a formative time in their lives, you want to create an environment where they can learn and flourish. A good mentor doesn't tell you exactly what to do, they just show you and lead by example, which I think is quite important.'

Cell scientist to watch – Mu He

Mu He is an Assistant Professor at The University of Hong Kong. She received her undergraduate degree from Cornell University in the USA and went on to pursue a PhD with Kathryn Andreson at the Memori...

journals.biologists.com

HHMI released the official 2027 Gilliam Fellowship details, and a lot changed. Deadline's earlier this cycle: Oct 27. Int'l & MD-PhD students now eligible. Stipend up to 50K. New postdoc pathway adds up to 7 yrs of support. No Journal names!!!! www.yaelcourtney.com/resources-an...

2027 HHMI Gilliam Fellowship: New Deadline, Eligibility, and Award Changes — Ya'el Courtney

HHMI's 2027 Gilliam Fellowship guide is out. What changed: an earlier October 27 deadline, expanded eligibility, a higher stipend, and a new postdoc pathway.

yaelcourtney.com

Does anyone have a protocol for arresting Expi293 cell cycle progression? We’ve tried some stuff and it hasn’t gone well…

What a game…

Congratulations to the 2026 KidneyCure Grant Recipients! 34 new investigators join 22 continuing grantees in a cohort of 56 researchers. More than $4 million in research funding supports their work advancing kidney research and improving patient care. 🔗https://www.kidneycure.org/pages/qa.aspx

Anyone else having this problem? NCBI has imposed such draconian CPU usage limits that BLAST has become unworkable. Do I need to go to AWS to get BLAST to work now?

Honored and delighted to be elected an EMBO Member. A huge thank you to our amazing team, this recognition wouldn't be possible without you. Perfect day to celebrate together during our lab outing! 🎉 - Virginie

EMBO@embo.org · last mo.

Welcome and congratulations to the 60 new members and 11 associate members who have been elected to the EMBO Membership! They join a community of more than 2,200 leading scientists. 🧪 https://www.embo.org/press-releases/seventy-one-leading-scientists-elected-to-the-embo-membership/ #EMBOMembers2026

Excited to share our review article on cilia disassembly, published in @jcellsci.bsky.social. journals.biologists.com/jcs/article/.... We highlight how disassembly of cilia occurs, ...

Primary cilium disassembly – from mechanisms to roles in physiology and disease

Summary: This Review explains how recent advances have expanded our models of how, when and where primary cilia disassemble and discusses emerging roles of altered disassembly in disease.

journals.biologists.com

Thi Nguyen's paper on ciliary PKA activity is now published at @plosbiology.org: journals.plos.org/plosbiology/... She developed a ciliary PKA activity sensor, then, inspired by recent work from @benmyerslab.bsky.social and Susan Taylor's labs, showed that SMO inhibits PKA within cilia. 1/6

Smoothened and ciliary GPCRs regulate ciliary protein kinase A activity involved in Hedgehog signal transduction

Hedgehog signaling in vertebrates is transduced by the transmembrane protein Smoothened (SMO) on the primary cilium, but the underlying mechanisms remain unclear. This study shows that SMO and ciliary...

journals.plos.org

Ooh! Ctenophores have organizers that probably use TGFbeta/Activin! Tickles both the develolmemtal biologist and the evolutionary biologist. Hilde Mangold would have loved this: www.nature.com/articles/s41...

A blastoporal organizer in a ctenophore - Nature

Experiments using the comb jelly Mnemiopsis leidyi and the sea anemone Nematostella vectensis reveal that the emergence of a core signalling pathway may have been a key innovation enabling the transit...

nature.com

With a motivating push from @christlet.bsky.social I made a new Fiji plugin, CurveMorph. The idea was to create a tool for kymograph generation along the dynamic (bending/shaking) filament shapes (microtubules, cilia, neurites, etc). The logo was made using the plugin. github.com/UU-cellbiolo...

What if damaged human kidneys could one day repair themselves? At MDI Bio Lab, Iain Drummond, Ph.D., and his team have identified inflammatory signaling pathways in #zebrafish capable of triggering the production of new, functional nephrons without injuring the kidney itself. 🧪 🐟🎸 #NephSky #RenalSky

How to Repair a Kidney Without Making Things Worse

mdibl.org

P.S.: If you are excited about how mechanics regulates cellular physiology, please reach out! My lab is actively looking for curious and creative students/postdocs to join our growing team and discover exciting new biology with us. cri.utsw.edu/faculty/henr...

Henry De Belly - Children's Medical Center Research Institute (CRI) | Dallas Texas

Children’s Medical Center Research Institute at UT Southwestern (CRI) is a joint venture of UT Southwestern Medical Center and Children’s ...

cri.utsw.edu

Congratulations Thi Nguyen, @konjikusicmia.bsky.social, Lorenzo del Castillo and Roshank Irannejad on this new paper! I'm proud of you all. Thank you, Dagmar Wachten, for editing. Everyone else, please send thoughts, comments, critiques and questions: plos.io/4v7vdnp

Smoothened and ciliary GPCRs regulate ciliary protein kinase A activity involved in Hedgehog signal transduction

Hedgehog signaling in vertebrates is transduced by the transmembrane protein Smoothened (SMO) on the primary cilium, but the underlying mechanisms remain unclear. This study shows that SMO and ciliary...

plos.io

PLOS Biology@plosbiology.org · 2mo ago

Vertebrate #Hedgehog signaling is transduced by transmembrane protein Smoothened (SMO) on the primary #cilium, but what is its mechanism? @reitergroup.bsky.social &co show that SMO & ciliary GPCRs regulate ciliary PKA activity to activate the Hedgehog pathway @plosbiology.org 🧪 plos.io/4v7vdnp

Vertebrate #Hedgehog signaling is transduced by transmembrane protein Smoothened (SMO) on the primary #cilium, but what is its mechanism? @reitergroup.bsky.social &co show that SMO & ciliary GPCRs regulate ciliary PKA activity to activate the Hedgehog pathway @plosbiology.org 🧪 plos.io/4v7vdnp

Congratulations, @konjikusicmia.bsky.social. It makes my heart well up to have this cohort named in memory of Zara, an extraordinary scientist.

Leading Edge Fellows Program@leadingedgeprogram.bsky.social · 2mo ago

We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/

FASEB Cilia and Centrosomes. Abstract submission deadline is TODAY! Come share your exciting science with the community! events.faseb.org/event/cilia-...

Important new work from Chia-Hsiang Chang, @nachury.bsky.social and colleagues identifying the composition of neuronal cilia in an unbiased way. Lots of surprises herein: www.science.org/doi/10.1126/...

In situ proteomics unveils specialized domains for extrasynaptic signaling on neuronal cilia

In situ proteomics and expansion microscopy reveal nanoscale organization of postsynaptic proteins on neuronal cilia.

science.org

Congrats to @unger-lucas.bsky.social, @luizaghila.bsky.social, ‪@cheralab.bsky.social‬ and colleagues on this new, interesting paper identifying a role for the transcription factor HNF1A in supporting ciliation (and thus Hedgehog signaling) in the developing gut: genesdev.cshlp.org/content/40/1...

Physicist Rosalyn Yalow co-invented a super-sensitive test (radioimmunoassay) that uses tiny amounts of radioactive tags to detect exact levels of insulin in blood & won the 1977 Nobel Prize in Physiology or Medicine (the 2nd woman ever to win in this category). She died #OTD in 2011. #WomenInSTEM

Zhengmao disarming a hefty LN2 canister. He cut the right wire. #MacGruber would have been proud.

Updated GRC Developmental Biology 2027 flyer/poster with the latest roster of invited speakers. 🌱🐟🧬🐭🪰🧪🧫 Come join us to discuss the latest in #devbio at the Renaissance Tuscany Il Ciocco Resort, Jan 17-22 ! #GRCDevBio2027

Christian Mosimann@chrmosimann.bsky.social · 3mo ago

*** GRC Developmental Biology 2027 - Jan 17-22 @ Renaissance Tuscany Il Ciocco Resort *** Join us for a fabulous 2027 Gordon Conference on all things #devbio & the trainee-led GRS! More info on registration, abstract submission, et al., here: www.grc.org/developmenta... #GRCDevBio2027 🧬🐭🐟🪰🌱❤️

I think this complex is very cool! Excited to see this in print @jennkong.bsky.social! 🧪 www.sciencedirect.com/science/arti...

Design principles of a membrane-spanning ubiquitin ligase

Receptor-type E3 ubiquitin ligases enable extracellular signals to control ubiquitylation in the cytoplasm, playing widespread roles in development, m…

sciencedirect.com

Only two more weeks to submit abstracts for the FASEB Cilia and Centrosomes. Abstract submission deadline is June 8. Submit an abstract and come share your exciting science with the community! events.faseb.org/event/cilia-...

Some tubulin (including centriolar microtubules) gets glutamate added post-translationally. This modification is evolutionarily ancient. New work from Irma Sánchez, Brian Dynlacht and colleagues @dynlachtlab.bsky.social identify an 8-component complex that does it: www.nature.com/articles/s41...