UW Madison Microbiology Doctoral Training Program

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Official Bluesky account for the UW Madison MDTP

New preprint from the lab led by Alex Dobrila! We show that butyrate-dependent toxin release in C. difficile is mediated by a broadly-conserved endolysin (EndD), which is under the control of the sporulation sigma factor SigK. Excited to share this story! 👇 www.biorxiv.org/content/10.6...

EndD mediates butyrate-dependent toxin release in Clostridioides difficile

Clostridioides difficile is an urgent threat to human health. Current treatments for C. difficile infections (CDIs) are antibiotics and microbiome restoration therapy (MRT) for recurrent cases. Howeve...

biorxiv.org