🚨 Job alert! 🚨 Join the faculty at UW–Madison Bacteriology! We have two faculty searches: • Asst Prof (Microbial Communities & Bioeconomy) • Asst / Assoc / Full Prof (Systems & Synthetic Biology) Check out the open positions and apply👇 #FacultyJobs #SynBio #Microbiology #Astrobiology #Evolution
Margaret Alexander
@margaretalexander.bsky.social
Assistant Professor UW-Madison, Medical Microbiology and Immunology investigating the mechanisms of diet, microbiota, and immune interactions in autoimmunity alexanderlab.mmi.wisc.edu views are my own
Very excited to share our lab’s 1st paper! In this study, we investigate how the ketone body BHB precursor BD shapes host-microbiota-immune interactions during enteric infection. shorturl.at/z9WXm Lead by the talented graduate student Wenxuan Dong in collaboration with the Caballero-Flores lab.
β-Hydroxybutyrate precursor 1,3-butanediol modulates enteric pathogen susceptibility and Th17 responses via commensal bacteria | mSystems
Diet is a key determinant of gut microbial composition and mucosal immune function, yet the microbial mechanisms linking diet-mediated metabolic changes to immune regulation remain incompletely unders...
shorturl.at
Cofession: OK I loved the book Project Hail Mary and very much enjoyed the movie. But I MUST vent!! In a movie about a spaceship that use CENTRIFUGAL FORCE for gravity they DO NOT BALANCE a centrifuge (which may have actually been a speedvac) when using for molecular biology. I died a little inside
Invest in the future of science! Support diversity in science especially when traditional sources have dried up. Donations helps empower the next generation of scientists. shorturl.at/AaPnp -PROPEL scimedgrs.wisc.edu
Donate to Solving For Science
Help support Solving For Science by donating or sharing with your friends.
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Join Marienela Yaritza Heredia (Post Doctoral Researcher), and Jessamine Kuehn (PhD student), and myself this Tuesday 11/11 at 6:30 at the newly opened One Social Food Hall for our discussion on the gut microbiome! There will be trivia, bingo, science, and fun!!
Two conferences, one reg! Sign up for Microbiome Metabolism & Metabolites + get Human Microbiome FREE. Joint keynotes: Emily P. Balskus & Mohamed S. Abou Donia. keysym.us/KSMicroMetab26 @pieterdorrestein.bsky.social @mfgrp.bsky.social @inesthiele.bsky.social #KSMicroMetab26 #KSMicrobiome26
Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease | Keystone Symposia
Join us at the Keystone Symposia on Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease, January 2026, in Banff, with field leaders!
keysym.us
#Throwback 🧪 PERSPECTIVE | Emerging tools and best practices for studying gut microbial community metabolism @cecilianoecker.bsky.social & P Turnbaugh
Emerging tools and best practices for studying gut microbial community metabolism - Nature Metabolism
In this Perspective, Noecker and Turnbaugh provide a detailed guide for studying microbial community metabolism and discuss the best practices in the field.
bit.ly
Interesting recent review on the links between gut microbes and T-cells, highlighting a mechanistic framework linking microbial metabolites to all stages of T-cell fate and function. 🔗 www.nature.com/articles/s41...
The role of gut microbial metabolites in the T cell lifecycle - Nature Immunology
Tran et al. discuss the role of the gut microbiome and gut microbiome-derived metabolites in T cell biology.
nature.com
🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025. 🔗 ow.ly/rwMU50Wy3Mp #AAIRESTORE
Microbiology professor, want to join a slack for microbiology professors, any career stage, diverse career types (pure teaching, med school, R1, community college, pure research fed PIs, ...) Message me for an invite link if you are interested. No imposter syndrome, if you are 1% micro, join!
BREAKING: A federal judge reversed National Institutes of Health's terminations of hundreds of critical research grants that were canceled because of their alleged connection to disfavored topics, including diversity, equity, inclusion, and gender identity. This is a major win for public health.
Estimated 15K+ in Madison WI A lovely shirt seen: One Thing Money Can't Buy: Wisconsin
New plan: As I am getting more and more spam texts I will just respond with links about science funding like this one: unbreaking.org/issues/medic...
Medical Research Funding — Unbreaking
How the administration is breaking the government, and what that means for all of us.
unbreaking.org
Each Friday night, I write up what happened in science & higher ed. - 1200+ pages of new (weird) detailed budget request - cancellation of pandemic flu & HIV vaccine efforts - more travel visas throttled - FEMA, “gold standard science” & more This was week 19: buttondown.com/liminalcreat...
Week 19
What now & what’s next in science and higher ed
buttondown.com
From helping farmers plan with better weather data to growing Wisconsin's semiconductor industry, discover some of the ways that @uwmadison.bsky.social research is improving lives and making the U.S. stronger. #WisconsinInnovates
Help Protect the Future of UW–Madison Research
Badger-led research strengthens communities, saves lives, and supports thousands of jobs. Learn why this work matters—and how you can support it.
news.wisc.edu
New research from @jordanbisanz.bsky.social et al. used machine learning to design C. difficile suppressive synthetic microbiomes. 🦠 This is a big step towards reducing antibiotic use & making a safer and more effective fecal microbiome transplant alternative. www.sciencedirect.com/science/arti...
A designed synthetic microbiota provides insight to community function in Clostridioides difficile resistance
Clostridioides difficile, a major cause of antibiotic-associated diarrhea, is suppressed by the gut microbiome, but the precise mechanisms are not ful…
sciencedirect.com
Happy to announce that MEDI, our method to quantify dietary intake through metagenomics is out now. 🧬 🧪🧫🦠 www.nature.com/articles/s42... #metagenomics #microbiome #microbiomesky So what is MEDI? A combination of two things:
Metagenomic estimation of dietary intake from human stool - Nature Metabolism
Diener et al. present a method that allows the estimation of dietary intake from human stool by detecting food-derived DNA in faecal metagenomes.
nature.com
Well. I have been informed that it is the weekend, again. When you are ready to sit down together & figure out what just happened and what to do, we’ve got you: buttondown.com/liminalcreat... It’s also okay if you’re coming in hot! “What the actual fuck??” is a sensible start place at the moment.
Week 3
Figuring out what to focus on now & what to focus on next in science and higher ed
buttondown.com
Starting my Bluesky adventure by highlighting a new paper from the lab!
"A human gut bacterium antagonizes neighboring bacteria by altering their protein folding ability" @cp-cellhostmicrobe.bsky.social @yalemedicine.bsky.social Andrew Goodman www.cell.com/cell-host-mi...
I’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War. Same link, new title and some updates.
Revised and Extended: What's Happening Inside the NIH and NSF
science.org
Happy to share our new paper in @naturemicrobiol.bsky.social on mapping spatial relationships of the human gut microbiome. We identified distinct spatial hubs between gut bacteria that reflect sub-community assemblies at the micron-scale. Led by Miles Richardson & co. www.nature.com/articles/s41...
SAMPL-seq reveals micron-scale spatial hubs in the human gut microbiome - Nature Microbiology
Split-And-pool Metagenomic Plot-sampling sequencing (SAMPL-seq) can be applied to complex microbial communities to reveal spatial co-localization of microbes at the micron scale.
nature.com
ASM website screenshots from the wayback machine in December '24 (web.archive.org/web/20241211...) vs today. Pretty disappointing!! 🧪
@vscooper.micropopbio.org and @mostlymicrobes.bsky.social while downloading scientist spotlights for teaching from the site; ASM has also scrubbed the entire IDEAA page including resources on LGBTQ+ scientists at asm.org/IDEAA/resources/pride-month
Out now in @nature.com: Gut microbiome diversity across African populations - a valuable resource for further research and foundational for global health equity. 🧪 www.nature.com/articles/s41...
Expanding the human gut microbiome atlas of Africa - Nature
A cross-sectional study from four African countries shows the importance of investigating the gut microbiome in previously under-represented populations and provides a framework for equitable microbio...
nature.com
@lizneeley.bsky.social is publishing a weekly newsletter to track the ongoing attacks in science and higher ed. If you want to keep abreast without drowning in the news, I recommend it: buttondown.com/liminalcreat...
Making Sense of It All
Hi! I’m Liz Neeley and I’m glad you’re here. Making Sense of It All is an outlet for my work at Liminal, which focuses on sensemaking in a noisy and complicated world. I built Liminal as an antidote t...
buttondown.com
The news cycle right now - even just for science & higher ed - is overwhelming. We have to do it, but fortunately, we don’t have to do it alone. My team is focused on tracking what’s happening to research funding, jobs & salaries, shared datasets, university responses & safety of our communities
Today we report a new compendium of human gut microbiomes with >168,000 samples By analyzing this massive dataset, we discovered distinct microbiome patterns across the globe, and show we can predict where a person lives just from their gut bacteria Now out in Cell: www.cell.com/cell/fulltex...
Integration of 168,000 samples reveals global patterns of the human gut microbiome
The Human Microbiome Compendium is a unified database of publicly available human gut microbiome 16S samples, built with the integrated data from hundreds of independent projects. The compendium is us...
cell.com
Microbiome science needs more microbiologists- A new commentary authored by myself and @abaumler.bsky.social www.nature.com/articles/s41...
Microbiome science needs more microbiologists - Nature Microbiology
Microbiome science is a multi-disciplinary field, but classical microbiologists are needed to ensure advances are grounded in our understanding of basic microbiological concepts.
nature.com
Our study @cellpress.bsky.social finds healthy Canadians that consume a non-industrialized-type #diet can modulate their #microbiome, boost beneficial metabolites and improve their health. In just 3 weeks: LDL cholesterol ↓17% fasting glucose ↓6% CRP ↓ 14% www.cell.com/cell/fulltex...
Cardiometabolic benefits of a non-industrialized-type diet are linked to gut microbiome modulation
Is it possible to restore the human gut microbiome in industrialized settings and reintroduce microbial species that have been lost? In healthy adults, Li et al. found that consuming a diet mimicking ...
cell.com
We are hiring a new faculty member in my dept at Minn State Mankato! This person will teach human anat/phys for bio majors and run a research program with undergrad and M.S. students. I'm happy to answer questions about what it's like here as new faculty!
Tenure Track Assistant Professor of Biological Sciences (Human Anatomy and Physiology, AA26057)
All Job Postings will close at 12:01 a.m. CT on the specified Closing Date (if designated). Working Title: Tenure Track Assistant Professor of Biological Sciences (Human Anatomy and Physiology, AA2605...
minnstate.wd1.myworkdayjobs.com
Always notable when the Lamming Lab drops more insight into the geroprotective effects of BCAA restriction. Never thought I’d say isoleucine is the coolest of the 3, but it is clearly super important! 😎 Awesome work!
Pleased to announce the publication of our new manuscript, "Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging" in Nature Aging today! www.nature.com/articles/s43... Free link: rdcu.be/d1DGk