valebodi.bsky.social
@valebodi.bsky.social
Surviving MyalgicE aka ME/CFS & AAG to tell the story, pwME & advocate w/ a JD. Into MEdical, Social, Climate Justice & Arts. ME-dical apolide, Human Neutrino, Gnarled pacer MEssland Worldwide https://www.tandfonline.com/doi/pdf/10.2217/fmb-2022-0031
A severe bout of COVID-19 can wake up an army of dormant viruses hiding inside the body go.nature.com/4fDUY9w
COVID can wake up a slew of dormant viruses inside you
Reactivation of typically harmless anelloviruses, in particular, seems to be linked with developing long COVID, study finds.
go.nature.com
In the Discussion section the researchers write that chronically infecting viruses are prevalent and that: - emerging evidence suggests that their reactivation may contribute to autoimmune diseases, malignancies and chronic fatigue syndrome.
Eric Topol@erictopol.bsky.social · 5h agoSevere Covid leads to persistent viral reactivation, with >10 different viruses noted in the first 40 days after hospital admission. Long Covid was specifically associated with reactivation of latent Anelloviridae virus @nature.com www.nature.com/articles/s41...
Although our results do not establish causation between virus reactivation and clinical outcomes, we highlight the prevalence of chronic viral reactivation during acute COVID-19 and long COVID. Our findings challenge the prevailing view that chronic viral reactivation is primarily a consequence of
Virus reactivation in acute and long COVID-19 - Nature
Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prog...
nature.com
There is an urgent need for professionals to learn more about #ME/CFS and it is hoped that these videos will continue to play a significant educational role. Dialogues for a neglected illness @dialoguesmecfs.bsky.social #ICD-10G93.3 #ICD-10G93.32 #ICD-118E49
Dialogues for a neglected illness - Dialogues
dialogues-mecfs.co.uk
Very severe #MECFS can cause profound suffering, extreme disability and life-threatening symptoms. Many are completely dependent on care, yet still face misunderstanding and inappropriate management. #SevereMEAwarenessWeek
Today everyone — EVERYONE — should take a moment and read Ray Bradbury's four-page short story from 1950.
Rebecca R Helm@rebeccarhelm.bsky.social · 22h agoToday is the day the story There Will Come Soft Rain is set. An amazing and heartbreaking work of fiction for our modern age. Read it here:
Today is the day the story There Will Come Soft Rain is set. An amazing and heartbreaking work of fiction for our modern age. Read it here:
a wooly man without a face@jojororo.bsky.social · yesterdayMitochondrial control of inflammation Your immune system treats broken mitochondria like invading bacteria because, evolutionarily, that's exactly what they once were. The molecular signatures persist. What determines health versus disease is how effectively your cells maintain mitochondrial
Mitochondrial control of inflammation - Nature Reviews Immunology
Lorenzo Galluzzi and colleagues discuss the molecular mechanisms through which mitochondrial dysfunction elicits inflammatory reactions, the cellular pathways that are in place to control them and how...
nature.com
Something significant just happened: for the first time since 2003, #MECFS will be counted separately in Australia’s burden of disease study. We have never been closer to real change. If #EmergeAustralia has supported you, please share @ your local MP. zurl.co/K7epR
Graphic source: Pg. 16 AR6 Synthesis Report — Climate Change 2023 www.ipcc.ch/report/ar6/s...
Take a careful look at this map. As these places begin to hit their adaptation physical limits, 100s of millions of people are going to be on the move. We are utterly unprepared.
Within the next 2 decades half the entire world’s infrastructure will be located in places where we can no longer survive. Half the global human population will need to migrate in the next 20 years just to survive.
They think they're being clever eugenicists by saying that people with "underlying health issues" don't matter, but >75% of U.S. adults have a chronic condition (including 60% of age 18–34). So what they're really saying is "nobody matters, it's okay if everybody dies from inadequate regulation."
The New York Times@nytimes.com · 2d agoBreaking News: Two deaths in Michigan have been linked to cyclospora. Both people who had the parasite also had underlying health issues.
I’m intrigued by the recent resurgence of the ‘Long Covid is not real’ nonsense we saw back in 20/21. The refusal to learn is one thing, but the dismissal of reality is another. Long Covid is too painful, too common & too present in many people’s lives to be denied. The story is hard to rewrite.
This interview between Nolan and Chinese academic and doctoral student Yiyang Zhuge is one of the best interviews I’ve seen in a long, long time. Skips past the routine questions about performances, IMAX cameras etc and really makes him work for his answers. youtu.be/wa4I8Ch2TRo?...
Christopher Nolan talks narrative decisions, film critics and whether he Christianised The Odyssey
YouTube video by Nolan Archives
youtu.be
“The findings are important for the way exercise-induced symptoms in post-COVID and ME/CFS are viewed. The results show that the symptoms cannot be easily explained by reduced physical activity or loss of fitness. The muscles of patients function differently in several respects than those of healthy
ME Research UK co-funded research: muscle problems in long COVID and ME/CFS cannot be explained by prolonged inactivity
A team of researchers – including ME Research UK-funded researcher Associate Professor Rob Wüst – has published a manuscript in the leading science journal, Nature Communications, highlighting that mu...
meresearch.org.uk
ADHD in women: Breaking the stereotypes Written by Maria Cohut, Ph.D. Why does it take longer for women to receive an #ADHD diagnosis? How does ADHD present in girls and women, and has the research been keeping up with the complex realities of this developmental condition? Prof. Davida Hartman,
ADHD: Why do women get missed out?
Why does it take longer for women to receive an ADHD diagnosis, and should our understanding of ADHD change? Prof. Davida Hartman, autism and ADHD specialist, joins In Conversation to answer these and...
medicalnewstoday.com
As we recall the trauma caused by COVID in 2020, we should not forget COVID continues to harm. Many still suffer from Long COVID, people who mask are often harassed, and we haven’t scaled clean air infrastructure. If we truly acknowledge past harms, we should be working to create a better future.
Preliminary findings using a PET tracer targeting activated astrocytes suggest a potentially revealing neuroinflammatory profile in #ME/CFS, with effects concentrated in the default mode network and possible difficulty switching out of resting networks. Watch full video here: youtu.be/BBIRZvHPc5E
Still the Most Underfunded Diseaseat the NIH in 2026 #ME/CFS #pwME Video by ME/CFS Quotes (2022)
The Most Underfunded Disease at the NIH
YouTube video by MECFS Quotes
youtube.com
Dysregulation of the Kynurenine Pathway, Cytokine Expression Pattern, and Proteomics Profile Link to Symptomology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome #ME/CFS (2023 🇦🇺) #KynureninePathway
Dysregulation of the Kynurenine Pathway, Cytokine Expression Pattern, and Proteomics Profile Link to Symptomology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) - Molecular Neurobiolog...
Dysregulation of the kynurenine pathway (KP) is believed to play a significant role in neurodegenerative and cognitive disorders. While some evidence links the KP to myalgic encephalomyelitis/chronic ...
link.springer.com
Conclusions A 62 EV-miRNA signature provides insight into the interconnected neuro-systemic pathways disrupted in ME/CFS, particularly those governing neuronal connectivity and cellular scaffolding. Within this candidate EV-miRNA signature, the top-ranked miRNAs—miR-21-5p, let-7f-5p, miR-26b-5p, and
Circulating extracellular vesicles-microRNAs as potential biomarkers for the identification of ME/CFS: differentiating fatigue-related conditions - Journal of Translational Medicine
Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating, multi-systemic condition that has gained renewed global attention due to its clinical overlap with the growing...
link.springer.com
Since then, there have been two Prevention of Future Deaths reports relating to severe #MECFS, but very little has changed apart from a few NHS training modules, which have had a remarkably low uptake.
It’s Severe ME Awareness Week. Here are some highlights from the explainer video on severe and very severe #MECFS I made in 2021. Experts discuss the lack of medical care, swallowing difficulties and tube feeding often being delayed until it becomes life threatening.
Audio version is available www.longcovidadvoc.com/post/bps
101: 03. The Biopsychosocial Model
To clearly name the problem: The term is accepted in medicine as a common-sense position that on the surface makes a great deal of sense. Yet, there is often a hidden psychosomatic interpretation that...
longcovidadvoc.com
No.03 in our 101 series covers The Biopsychosocial Model. A vital topic as much of our clinical care is BPS. Lack of progress in care, research & treatment rests on this theory. Yet, it's a complex topic, so we have created an accessible article AND a 1-page visual summary. Link 👇
