Victor de Lorenzo (CNB, Madrid)

@vdlorenzo.bsky.social

Synthetic Biology with a Southern European flavour for a new partnership with the Living World https://vdl-lab.com/ http://seva-plasmids.com/

1/3. 50 yr after the (in)famous Asilomar meeting which set a risk-paranoid & control-centered mindset of Gen Eng—with consequences reach us to this day—a large number of diverse SynBio stakeholders gathered again in the same place to revisit many of the standing issues with fresh perspectives.

We know the peer review system is under heavy criticism. But can anyone propose anything better? I just received the reviews of two of our most recent submissions. They were very critical but immensely helpful. The peer review system has many flaws, but don’t throw the baby out with the bathwater 🙄!

@sevaplasmids.bsky.social are a fantastic community service and they work very nicely!!! 👏👏👏Thanks for highlighting our work (@davidalbesa.bsky.social) 😊, the SEVA plasmid was instrumental to control Tke5 toxin expression. Highly recomended!!!

SEVA Plasmids@sevaplasmids.bsky.social · 2w ago

Tke5: A new weapon against crop-killing bacteria! 🌾⚠️ This toxin kills harmful plant pathogens by forming pores in their membranes. 🦠 #SEVA ⭕ allowed controlling its expression safely during the study. Read more: shre.ink/31qa

Thanks, Victor. I’m proud of what we have done on this. It is sad to see that, as the window of opportunity to change things closes, the worst predictions from 30 years ago are becoming reality, while those with political responsibility often fail to understand that this is an existential threat.

The Madrid region is burning. We have never witnessed wildfires on this scale here. This is both frightening & infuriating. We all knew that climate change would make these events more frequent & extreme. Prevention cannot be left to good luck or the hope that this year will somehow be different 😡

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A SEVA plasmid name ⭕ can tell you all you need to know. Just read the code: 🔹Selection marker 🔹Replication module 🔹Cargo 🔹Additional gadgets Standards make life easier. Learn more about nomenclature 👉https://acortar.link/XZmJVZ

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The term *agency* a growingly popular word among evol biologists, has no equivalent in Spanish. I had many discussions about the notion. The way @philipcball.bsky.social describes it sounds like a materialist version of vitalism that reminds me of Monod’s disgressions on teleology vs teleonomy 🤔?

Philip Ball@philipcball.bsky.social · last mo.

My latest piece for @quantamagazine.bsky.social might stir the pot somewhat. It takes on the contentious notion that biological organisms can be considered to possess agency. www.quantamagazine.org/is-life-just...

1/2 If I were a bacterium 🙄 in the wild, I would welcome beneficial information from my neighbors, while rejecting fake or predatory stuff. Should not microbes discriminate between good from bad info coming. Rejecting all of it upfront looks like a bad evol idea … 🤔 www.biorxiv.org/content/10.6...

Widespread immune systems protect bacteria against conjugative plasmids

Conjugative plasmids are a class of mobile genetic elements capable of efficient transfer between bacterial cells. Although they can introduce beneficial traits such as antibiotic resistance to recipi...

biorxiv.org

“La revisión por pares es imperfecta, cara, lenta y a veces injusta, pero sigue siendo lo único que separa un descubrimiento de una nota de prensa bien redactada. Cuando la eliminamos, no democratizamos la ciencia: la dejamos a merced de quien tenga mejor gabinete de comunicación.“

Patricia Fernández de Lis@pflis.bsky.social · last mo.

¿Es este el final de la ciencia como la conocemos? El anuncio de la creación de la vida en un laboratorio es una prueba más de que la ciencia avanza hacia un sistema de publicación sin revisión con consecuencias inciertas elpais.com/opinion/2026...