Excited to share the newest work from the lab, examining the role of dorsal striatum astrocytes and neurons in alcohol stimulation. Huge congrats to superstar postdoc @cherishardinger.bsky.social and the team on this beautiful work! www.biorxiv.org/cgi/content/...

Cherish Ardinger, PhD@cherishardinger.bsky.social · 2mo ago

You’re at the bar having that first drink of the night 🍻 the excited, energized feeling you may have is the “stimulant response” to alcohol - a risk factor for alcohol use disorder. We researched an understudied cell-type’s role in this response #neuroskyence www.biorxiv.org/cgi/content/...

Our work with Pablo Tano, @hyunggoo-kim.bsky.social Athar Malik, Alexandre Pouget and @naoshigeuchida.bsky.social exploring how dopamine neurons could enable multi-timescale reinforcement learning in the brain is out in @nature.com www.nature.com/articles/s41...

Multi-timescale reinforcement learning in the brain - Nature

Individual dopaminergic neurons encode future rewards over distinct temporal horizons.

nature.com

My laboratory at Université Laval in Québec City, Canada, is looking for a postdoc to study how neuromodulatory systems impact cortical processing during foraging behavior. This fully-funded position offers a collaborative environment in a great city. More info👇 can-acn.org/postdoctoral...

First pre-print from the lab: www.biorxiv.org/content/10.1...

System-wide dissociation of reward and aversive dopaminergic signals

Dopamine is central to reinforcement learning, classically linked to reward prediction error signaling. However, recent findings suggest a more complex picture, with dopamine neurons responding to ave...

biorxiv.org

Together with @macshine.bsky.social & @elimuller.bsky.social we have a cool interdisciplinary project on compositional cognition, and we’re looking for a PhD student. More details here www.findaphd.com/phds/project... DM or email any questions Please RT or pass on to interested students. Thanks!

I honestly think LLMs are very useful tools, but this kinda shit shows the real danger with these models: Stupid people with important roles will use them for purposes they are not well suited for.

Navin Pokala 🇺🇸🇺🇦🇨🇦🇬🇱@navinpokala.bsky.social · last yr.

Check out a new lab paper from Mayumi Watanabe's thesis work showing how different subregions of medial prefrontal cortex differentially regulate extinction of aversive memories through projections to the locus-coeruleus-noradrenaline system: doi.org/10.1038/s413...

Bidirectional emotional regulation through prefrontal innervation of the locus coeruleus - Molecular Psychiatry

Molecular Psychiatry - Bidirectional emotional regulation through prefrontal innervation of the locus coeruleus

doi.org

Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8

Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)

Reminder: They're trying to demoralize you, and they're doing a great job of it. Part of resisting is making time for joy despite the attempts to make you feel this is not the time for it. Love your people. Dig the art that speaks to you. Go to the places where life flows into you. You deserve joy.

The first paper from the lab! What started as a simple comparison between zebrafish lines turned into an analysis of sensorimotor development in zebrafish larvae: doi.org/10.1016/j.bb...

Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube! Please like and repost to help us get the word out! www.youtube.com/playlist?lis... Lecture 1: Signals and data acquisition Focusing on hardware, digital/analog I/O, synchronization 🧵

Neuroscience methods - YouTube

Nanocourse: Approaches to Study Neural Circuits This course was taught by Anita Autry, Tiago Gonçalves, and Luke Sjulson at Albert Einstein College of Medici...

youtube.com

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏 www.nytimes.com/2024/12/09/h...

Sharing here our most recent preprint and the work of Laurence, PhD student extraordinaire, implicating 🧠 #pericyte in stress responses 🐭 and human depression 😞 www.researchsquare.com/article/rs-5...

I am recruiting graduate students for my lab @mcgillu.bsky.social for admission in Fall 2025! Get in touch if you're interested in how brain circuits implement distributed computation, including dopamine-based distributed RL and probabilistic representations.

🚨Job Alert 🚨 Join our vibrant team ! My neuroscience 🧠 research lab at @mcmasteruniversity.bsky.social located in Hamilton, Ontario, Canada is looking for a laboratory technician - please see the job posting here and apply. bit.ly/4g3dNA6 Feel free to reach out with any questions!

The call for participating in the Summer School Frontiers in Neurophotonics June 2nd to 13th, 2025 in Quebec City, Canada is now open! One of my trainees went last year and had a great experience, so I wanted to recommend it! neurophotonics.ca/frontiers-in...

After popular demand (thanks @martinowk.bsky.social 😅) here a small representation of our #bluespot crowd! Please share and let me know if I missed someone! go.bsky.app/DyBTCRF

New preprint: In this work done by Gabi Drummond they showed that the updating of behavior following unexpected stimuli is mediated by sustained response of astrocytes in the prefrontal cortex. Fun collaboration with the Surlab! #astrocytes #locuscoeruleus www.biorxiv.org/content/10.1...

Cortical norepinephrine-astrocyte signaling critically mediates learned behavior

Updating behavior based on feedback from the environment is a crucial means by which organisms learn and develop optimal behavioral strategies. Norepinephrine (NE) release from the locus coeruleus (LC...

biorxiv.org

Neurophotonics is now on Bluesky! For our first post here, we'd like to announce the opening of the call for participation to the Summer School Frontiers in Neurophotonics! Visit neurophotonics.ca/school for more info about this school that combines lectures and hands-on experiments

You love cutting-edge 🔬 imaging 🧠 science 🧪 and want to learn about the latest tools and techniques and as a bonus visit Quebec City in June? Here is your chance! 🤓

The Neurophotonics Centre@neurophotonics.bsky.social · 2y ago

Neurophotonics is now on Bluesky! For our first post here, we'd like to announce the opening of the call for participation to the Summer School Frontiers in Neurophotonics! Visit neurophotonics.ca/school for more info about this school that combines lectures and hands-on experiments