Not sure how to visualise your connectome data? Check our latest led by @m-gajwani.bsky.social & C Adamson on NeuroMarvl: an open source web-based platform for visualising and sharing connectomes! Paper: tinyurl.com/2t7ftu9d Software: tinyurl.com/yrv3xja3 @nsb-lab.bsky.social
Claire O'Callaghan
@claireocallaghan.bsky.social
Working in neuroscience etc. Sydney, Australia
Small piece in @natmentalhealth.nature.com, calling for greater recognition in the cognitive and computational neurosciences of how weird ligand-receptor interactions are - with @alexpiot.bsky.social, Sunjeev Kamboj and Ravi Das www.nature.com/articles/s44...
Embracing pharmacological complexity - Nature Mental Health
Nature Mental Health - Embracing pharmacological complexity
nature.com
Starting September 1, I will be working with a team to start a new research center at the Max Planck Institute for Human Development in Berlin. We currently have a couple of positions posted but there will be more so if you are interested stay tuned and feel free to get in touch.
📣 New research center on the horizon! The Center will study how midlife autonomic changes may contribute to #neurodegenerative disease risk, focusing on the locus coeruleus, #Alzheimer’s biomarkers, and emotion–cognition interactions. Interested? CAAN-Job openings 👇 www.mpib-berlin.mpg.de/career
1/ New paper out today from my group, in @natneuro.nature.com, in which we review the anatomical & functional data on insula structure across species. This was a "whole lab" project led by @joeycharbonneau.bsky.social. It's been a 5 year in the making (a full 3 years in review)! rdcu.be/fyd7T
Comparative insights into insula structure and function
Nature Neuroscience - Charbonneau et al. compare how the insula is structured and functions in humans, monkeys and rodents, revealing similarities and differences across species that are likely to...
rdcu.be
pyhctsa is out! A native Python port of the majority of the hctsa feature library (highly comparative time-series analysis). Thousands of interpretable time-series features available via a pip install. Built by Joshua Moore. Paper: doi.org/10.21105/jos... Code: github.com/DynamicsAndN...
If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets: "Revisiting nerve nets: functional organization and evolutionary implication" https://link.springer.com/article/10.1038/s44318-026-00879-w […] [Original post on biologists.social]
***New preprint from the lab*** showing “Generative replay across hippocampal-neocortical circuits”. In sleep we show spiking sequences in V1 (sensory neocortex!) that represent information that has not been directly experienced www.biorxiv.org/content/10.6... @bndu.ox.ac.uk @ndcnoxford.bsky.social
Generative replay across hippocampal-neocortical circuits
To make flexible decisions, the brain needs to make inferences between events that were not directly experienced together. In sharp-wave ripple (SWR) events, during periods of rest and sleep, spiking ...
biorxiv.org
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restorescience.com.au
You have 3 more days to prepare your abstracts for posters, orals and blitz talks at NeuroAlliance This is the first ever joint meeting of Australasian Neuroscience, Cognitive Neuroscience and Biological Psychiatry societies neuroalliance26.eventsairsite.com/call-for-abs...
🧠 A new paper from our lab is out! In this study, we explore how dorsal raphe nucleus (DRN) circuits modulate forebrain activity and behavior. www.nature.com/articles/s41...
Topographically organized dorsal raphe activity modulates forebrain sensory-motor representations and contributes to defensive behaviors - Nature Communications
Functional heterogeneity of dorsal raphe nucleus is not fully understood. Here authors show topographically organized sensory and locomotor responses from the zebrafish dorsal raphe and its forebrain ...
nature.com
Out today on @nature.com! Connecting neural specialization, population geometry, and their functional implications across the cortical hierarchy. So grateful for this beautiful and fun collaboration with @shuqiw.bsky.social, S Muscinelli, L Paninski, and @stefanofusi.bsky.social!
Rarely categorical, highly separable representations along the cortical hierarchy - Nature
Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.
nature.com
Optimism as naturalistic behaviour: https://osf.io/t2gka
Our new paper with lead and corresponding author Luis Yañez-Guerra on placozoan monoamine GPCRs and the "Prebilaterian origin of monoaminergic signaling" […] [Original post on biologists.social]
Our new preprint is out!! The human brain runs on ~20 watts. Computers and modern AI systems require vastly higher energy. This gap raises a fundamental question: how does the brain compute so efficiently? In our new study, we take a critical step toward measuring and understanding this directly 1/3
Learning Shapes the Energy Cost of Neural Tasks https://www.biorxiv.org/content/10.64898/2026.07.01.735889v1
Interested in the principles shaping connectome architecture? See our latest in @cp-cell.bsky.social led by F Normand @nsb-lab.bsky.social A simple model using geometric eigenmodes captures cortical connectomes of different species. Paper: tinyurl.com/3r43spf5 Thread: tinyurl.com/vx74hp6u
The YouTube channel of @kurzgesagt.org made a great and accessible video on how memories are stored in our brains. I wrote a blog post to provide additional context and details for those interested in the view of a neurophysiology researcher: gcamp6f.com/2026/06/22/w...
What happens inside your brain when you form a memory?
Kurzgesagt is a Youtube channel that breaks down science topics for a broad audience. They have great videos, both in terms of narrative, animation, and scientific accuracy. A few days ago, the cha…
gcamp6f.com
Interested in how dysregulation of locus coeruleus-norepinephrine circuits contribute to neuropsychiatric symptoms in early Alzheimer's disease? Check out our new review article from freshly minted Dr. Anu Korukonda! www.nature.com/articles/s41...
A new hope: locus coeruleus-norepinephrine system at the nexus of neuropsychiatric symptoms - Molecular Psychiatry
Molecular Psychiatry - A new hope: locus coeruleus-norepinephrine system at the nexus of neuropsychiatric symptoms
nature.com
🎉 Registration is now OPEN for the 2026 OHBM Australian Chapter Annual Meeting! 🇦🇺🧠🇦🇺 Get your ticket now! 🎟️🎟️🎟️ Registration: events.humanitix.com/ohbm-austral... 📝 Submit your abstract: docs.google.com/forms/d/e/1F... 🏆 Nominate a colleague (or yourself) for an award: ohbm-aus.github.io/awards/
OHBM Australia Meeting 2026
Uniting the Australian human brain mapping community.
events.humanitix.com
So I built a small tool that merges Allen CCFv3 with the traditional bregma-relative coordinate system (calibrated with Paxinos & Franklin's Atlas). Click any coronal or sagittal section, and get coordinates instantly. bohanzhao.com/Atlas Hope it saves someone a headache 🐭
Mouse Brain Stereotaxic Coordinate Viewer
Free interactive tool: enter bregma-relative AP/ML/DV coordinates to navigate Allen Mouse Brain Atlas coronal and sagittal sections. Brain regions identified in real time.
bohanzhao.com
SUITPy 2.1 is here - a Python-version of our toolbox for cerebellar isolation, normalization, atlassing, and flatmap visualization. The processing pipeline now works fully automatically from birth to old age. suitpy.readthedocs.io www.biorxiv.org/content/10.6...
In this new blog post, I review some several recent studies on dendritic voltage and calcium imaging in hippocampus: gcamp6f.com/2026/05/19/d... Great work by @bhlee1117.bsky.social, Xiang Wu, @adamezracohen.bsky.social, Attila Losonczy, Balazs Rosza, Kevin Gonzalez, and others!
Dendritic imaging of pyramidal neurons in mouse hippocampus
Dendrites are the tree-like arborizations of neurons through which they receive input from other neurons. This compartmentalized anatomy has given rise to the idea that individual dendrites process…
gcamp6f.com
Frustrated with DSM? Interested in @hitop-system.bsky.social as a potential alternative? Check our latest, led by J Tiego, using a bottom-up approach in a transdiagnostic twin sample evaluating the validity & heritability of the HiTOP model: osf.io/preprints/ps...
1/10 When the going gets tough, the dendrites get going. Here is a summary on our new paper just published in @science.org on flexible learning in frontal motor cortex. With @mattlark.bsky.social 🔬. #neuroskyence #neuroscience 🔗 doi.org/10.1126/scie...
Tuft dendrites in frontal motor cortex enable flexible learning
Flexible learning relies on integrating sensory and contextual information to adjust behavioral output in different environments. The anterolateral motor cortex (ALM) is a frontal area critical for ac...
doi.org
Astrocytes do so much more than any of us thought - they even communicate among specific brain regions across hemispheres! The journey to this paper spanned nearly a decade, but I'm most excited to see what everyone else does with the tools we've built. There's so much for all of us to explore!
Astrocytes connect specific brain regions through plastic networks - Nature
Communication between distant brain regions is mediated by plastic networks of gap junction-coupled astrocytes.
nature.com
We're hiring! Looking for a postdoc to work at UNSW Sydney, studying impacts of reward and information on attention, using eye-tracking, EEG, and modelling - with Kelly Garner, Daniel Pearson and me. Application link below, please spread the word! external-careers.jobs.unsw.edu.au/cw/en/job/53...
Research Associate - Psychology
The Research Associate (Level A) is expected to contribute towards the research effort of UNSW and to develop their research expertise through the pursuit of defined projects relevant to their particu...
external-careers.jobs.unsw.edu.au
Delighted to share our discoveries about one of the brain's neurotransmitter systems: www.biorxiv.org/content/10.6... Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1
biorxiv.org
What do #neuromodulators do in the #brain? Two recent papers give new insights: @nishantjoshi.bsky.social shows they do not only reshape individual cellular properties, but also the architecture linking them, thereby expanding the computational repertoire. www.biorxiv.org/content/10.6...
biorxiv.org
Wait… localized norepinephrine transients in the awake visual cortex?! Who would have guessed this neuromodulatory signal is that spatially precise, right where visual processing is happening. Brain state control just got a lot more local. @ruedigersarah.bsky.social www.nature.com/articles/s41...
New paper in PNAS! When the mind wanders, it often drifts to the body. We call this "body-wandering". These thoughts are often negative, but are associated with reduced ADHD & depression symptoms, driven by a distinct interoceptive-allostatic brain signature. pnas.org/doi/10.1073/pnas.2520822123