Vincent Burrus 🇨🇦💙💛

@vincentburrus.bsky.social

Microbiologist, conjugative plasmid fanatic, genomic island freak, weather enthusiast, computer geek, green thumb, dog lover, and chocolate snob - Science rules! 🇫🇷🇨🇦🏳️‍🌈

Neither Conservative nor Liberal Canadian gov'ts understand how university research works. They think that a few top people are key, don't provide increased funding once these hotshots move in, so that more proposals are chasing the same $. Lots of 🇨🇦 talent unfunded and unseen. 🧪

Monica H Green@monicamedhist.bsky.social · 5mo ago

Absolutely essential reading for anyone considering those "unicorn" hiring positions in Canada. Observations from researchers who are already there: www.nature.com/articles/d41... 🧪

academic.oup.com/nar/article/... Collaboration with Y. Yamaichi. Killing donor bacteria in conjugation mixes using water enables transcriptomic profiling of early plasmid genes ! Superb tool for studying zygotic induction of these early genes, which include anti-SOS and anti-RM factors. #microsky

Selective elimination of donor bacteria enables global profiling of plasmid gene expression at early stages of conjugation

Abstract. Conjugative plasmids are a major driving force for the dissemination of antimicrobial resistance. During conjugation, plasmid DNA is transferred

academic.oup.com

Needless to say, it also helps when the institution provides professional help for grant writing, which is not the case in smaller universities. Large study of scientists who move their labs reveals how location drives productivity | Science | AAAS www.science.org/content/arti...

Large study of scientists who move their labs reveals how location drives productivity

Concentrating funding at high-powered universities can maximize output, paper argues, but may sacrifice broader benefits

science.org

Join the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩 Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭! Please visit my lab's webpage for details about the position and how to formally apply.

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🔬 Ph.D. position in Environmental Microbiology The LCPME is offering a 3-year Ph.D. position to work on the biology of conjugative plasmids carrying antibiotic resistance genes in environmental contexts. This project will combine bacterial genetics, microcosm experiments, and bioinformatic.

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Réservez les dates! Le BiSP (bactériologie intégrative, symbiose et pathogénèse) aura lieu le 5 et 6 novembre à l'Université de Sherbrooke - un événement qui sera en "symbiose" avec le MicrHub, rencontre annuelle de tous les microbiologistes de Sherbrooke. À ne pas manquer!

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Officially published now: RDFs for Large Serine Integrases that are moonlighting proteins. With collaborators the Olorunniji group @femijohn.bsky.social we find the TG1/phiC31 family RDF is an SSB, and the Bxb1 RDF has the fold and activity of an exonuclease. academic.oup.com/nar/article/...

Large serine integrases utilise scavenged phage proteins as directionality cofactors

Abstract. Recombination directionality factors (RDFs) for large serine integrases (LSIs) are cofactor proteins that control the directionality of recombina

academic.oup.com

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1/5 Can random sequences encode meaningful functions and allow de novo gene birth? To explore this, Michael Laub and I screened 100 million random genes, without sequence similarity to natural genes, for their ability to rescue growth arrest of E. coli cells producing the ribonuclease toxin MazF.

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